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Health Plan News

Timely Health Plan News and Commentary

Health Plan News
Home Archives for Public Health and Research

Public Health and Research News

Public health is the work of protecting the health of entire populations rather than individual patients: tracking disease, preventing outbreaks, promoting vaccination and screening, and studying what actually improves health outcomes. Research findings and public health data also drive coverage decisions, because health plans and regulators rely on evidence when they decide which services, screenings and treatments to cover.

What We Cover

This section covers public health developments and medical research with consequences for patients and health plans. That includes infectious disease, including COVID-19 and influenza; chronic conditions such as diabetes, heart disease, obesity and cancer; Alzheimer's disease and dementia; mental health and substance use; maternal and child health; and studies on health care costs, outcomes and access. We report on guidance from the Centers for Disease Control and Prevention (CDC) and the National Institutes of Health (NIH), and on peer-reviewed research and survey data.

How We Report Research

A single study rarely settles a question. When we report research, we identify who conducted and funded it, how large it was, and whether the findings are preliminary. This content is news and general information; it is not medical advice, and readers should discuss treatment decisions with a licensed clinician.

Research and public health news connects to our other sections. Drug approvals and vaccine coverage appear in Prescription Drugs and Pharmacy, preventive services coverage appears in Health Insurance Coverage, public health policy appears in Healthcare Policy and Law, and research on aging appears in Senior Care.

The latest public health and research news appears below, newest first.

Global Health Care Market Is $5.5 Trillion and Growing Quickly, Says Plunkett Research

Posted on December 8, 2010 Written by Editor

SOURCE: Plunkett Research, Ltd.

HOUSTON, TX–(Marketwire – December 8, 2010) –  Plunkett Research, Ltd. has released its newest market research and competitive analysis report, Plunkett’s Health Care Industry Almanac, 2011 edition, which identifies and analyzes major trends shaping the health care industry.

According to Jack W. Plunkett, CEO of Plunkett Research, Ltd., “While total health expenditures continue to grow in the U.S., health care is spreading rapidly in emerging nations like India and China.”

Major trends affecting the Health Care Industry analyzed in Plunkett’s report include:

  • Continued rise in health care costs.
  • Employers push health care costs onto employees.
  • Medicare and Medicaid spending continue to surge.
  • Health Care Reform Act of 2010 set to bring big changes.
  • Major drug patents expire while generic growth continues.
  • Quality of care and health care outcomes data become available online.
  • Obesity sparks government action.
  • Health care thrives offshore, medical tourism grows.
  • Disease management programs take root.
  • Health care industry to grow rapidly in China and India.

“Eventually, innovative health practices and technologies developed for lower-income nations will migrate to the U.S., helping to contain costs,” said Jack Plunkett.

A complete report with detailed industry trends and statistics analysis is provided in Plunkett’s Health Care Industry Almanac, 2011 edition. This informative reference book gives you the competitive intelligence you need, with a detailed industry overview, industry analysis and market research. Plus, thousands of contacts for business and industry leaders, industry associations and industry sites, as well as statistical tables, an industry glossary and thorough indexes — everything you need all in one value-priced, easy-to-use package.

A complimentary video of Plunkett discussing these trends is now available on the Plunkett Research website, as well as YouTube, and an Introduction to the Health Care Industry can be viewed at Plunkett’s website. 

About Plunkett Research, Ltd.
Plunkett Research is a leading provider of industry trends analysis and market research. Our reports and data services are used by the world’s top corporations, consultants, universities, libraries and government agencies. Plunkett’s products save time and effort when you need competitive intelligence, market research or marketing data. For more from Plunkett Research, become a Fan on Facebook and subscribe to our YouTube channel.

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Filed Under: Public Health and Research

incentaHEALTH Finds Better Way to Fight Employee Obesity While Reducing Employer Health Care Costs

Posted on December 8, 2010 Written by Editor

SOURCE: incentaHEALTH

Workplace Kiosks Screen and Measure Employee Health, Emails Motivate Increased Participation and Success Is Met by Cash Rewards

DENVER, CO–(Marketwire – December 8, 2010) – Like the scale in the doctor’s office, the numbers can be daunting. Similarly, the statistics that reveal an increasingly overweight America — 67 percent and rising — are sending shivers down the spine of this nation’s health care system, especially in corporate America where the costs of keeping employees healthy are threatening both the bottom line and the country’s economic future.

Today it costs employers an estimated $13,000 annually to provide premium health care benefits for a typical employee and his or her dependents, and that figure has gone up 10 percent each year for the past decade. Of that annual amount, almost $10,000 is paid by the employer. 

In an attempt to stem the tide, Denver-based incentaHEALTH has focused on one of the biggest drivers of health care costs: obesity. Overweight and obese employees incur over $1,500 in additional costs for the employer each year. In response, incentaHEALTH has developed a unique program that pays employees and their families to lose weight, stay healthy and remain productive. Blending technology, ingenuity, medical expertise, and employer resources, it is designed to encourage greater participation by employees in typical company health plans.

According to Todd McGuire, Chief Technology Officer, who co-founded the company in 2002 with CEO Jack Rule, the idea for incentaHEALTH was developed after discovering that among the most pressing issues facing the business world at the time were runaway health care costs and obesity.

“In 2002 we weren’t happy with the wellness programs used by the rest of the industry, so we created our own,” McGuire said. “Our technology authenticates health outcomes instead of relying on people to self-report. Since we are paying cash incentives, you don’t want somebody to send a friend down to weigh in for them.”

The centerpiece of the incentaHEALTH system is the patented HEALTHspot kiosk which, when strategically placed throughout a company’s facilities, provides:

  • Automated biometric measurements of weight, blood pressure and body mass index (BMI) using authenticated measurements (not self-reported)
  • Instant feedback to participants and program administrators
  • 24-hour, low cost operation and remote maintenance
  • Enhanced privacy
  • Full-body digital imaging to keep track of participant progress and create a visual progress report
  • Complete and accurate electronic records for both employee and employer

Supporting the kiosks, the program uses a variety of communication tools to reach all employees and motivate them to participate. Says McGuire, “Behavior change is a daily battle. It won’t occur with an occasional newsletter. A better approach is a daily coaching plan using emails and text messages that shows employees and their dependents exactly how to eat and exercise.” The program incorporates onsite kickoff sessions and printed support materials to reach employees without email access.

“The national view of health and wellness has matured significantly since we started our business,” said McGuire. “After extensive research of the problem and conducting surveys of the workforce, the wellness industry has found that people are inactive, overweight, have high blood pressure and are not eating properly. Employers are now demanding programs that result in real behavioral changes to tackle these issues.”

“Historically, employers have offered $50 to employees just to sign up for a wellness program, whether they used it or not,” he added. “What we do is shift from an incentive for participating to an incentive for measured performance. For example, if an employee signs up for our program and achieves a 15 percent weight loss, they will get paid, in actual dollars on a brightly colored check, when they weigh in at the HEALTHspot kiosk every 90 days.” The program pays incentives ranging from $15 to $150 per quarter to all employees based on the amount of weight they lose, so every level of success is rewarded.

So far, the incentaHEALTH approach to corporate wellness is working. Organizations across the globe are signing up — companies like Jackson National Life Insurance Co., Virginia Tech, Kaiser Permanente, Long Beach Memorial Medical Center, Accident Fund Insurance Company of America, U.S. Department of Health and Human Services, and others that are concerned about their employees’ health.

“incentaHEALTH has become an integral part of our overall wellness program, which helps our associates make healthier lifestyle choices,” said Cheng Hsu, benefits manager at Jackson National.

And users are noticing a big difference in their health.

“I’ve lost 70 pounds on this program. I am now eating healthy, watching my portion sizes and exercising,” said one employee participant. “It was a true godsend.”

About incentaHEALTH
incentaHEALTH is an innovative health care technology company based in Denver, Colorado. incentaHEALTH’s fully outsourced, employee weight management program is designed to help organizations reduce their health care costs by offering incentives to employees for improving their health. This is achieved by helping employees manage their weight through the use of interactive email coaching, workplace weigh-ins on private kiosks, and cash rewards for maintaining long term health improvements. For more information, visit www.incentahealth.com.

Media Contact:
Les Goldberg
Lages & Associates
(949) 453-8080
[email protected]

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Filed Under: Public Health and Research

Radient Pharmaceuticals Onko-Sure(R) In Vitro Diagnostic Cancer Test Potentially Effective as Veterinary Cancer Tumor Marker

Posted on December 8, 2010 Written by Editor

SOURCE: Radient Pharmaceuticals Corporation

TUSTIN, CA–(Marketwire – December 8, 2010) – Radient Pharmaceuticals Corporation (RPC) (NYSE Amex: RPC) today announced it has completed a pilot clinical study to measure the feasibility of using its Onko-Sure® in vitro diagnostic (IVD) cancer test kit as a veterinary tumor marker initially for cancer detection in domestic cats.

Preliminary data from the Onko-Sure® assay pilot study measuring domestic cat serum suggests RPC’s Onko-Sure® IVD cancer test may potentially detect cancer in domestic cats. In this pilot study, RPC ran samples from confirmed normal domestic cats and domestic cats with cancer. For cats with cancer, RPC ran a serum sample obtained first when the cats were cancer-free and another sample subsequently when the cats were confirmed with cancer. The relative levels of Onko-Sure® for the cats were compared using the Onko-Sure assay and showed a 2,853% increase in Onko-Sure levels versus the healthy sample. RPC is currently engaged in full clinical trial including 71 samples, which includes an antigen characterization that involves testing to identify direct evidence that RPC’s Onko-Sure® IVD cancer test kits are effective in cancer detection in domestic felines.

According to Douglas MacLellan, Chairman and CEO of Radient Pharmaceuticals, “This development is anticipated to open the use of our Onko-Sure® assay as a veterinary cancer tool that could play an integral role in the screening and early detection of cancer for veterinary patients and further enhance RPC’s strong portfolio of novel oncology products. This is truly an exciting development for the Company and our valued shareholders.”

Onko?Sure is a simple, non?invasive, patent?pending and regulatory?approved IVD test for use as an aid in early detection of cancer. Onko?Sure enables physicians and their patients to effectively monitor and/or detect certain types of cancers by measuring the accumulation of specific breakdown products in the blood called Fibrin and Fibrinogen Degradation Products (FDP). FDP levels rise dramatically with the progression of cancer. Onko?Sure is approved by the US FDA for the monitoring of colorectal cancer, Health Canada as a lung cancer screen and cancer monitoring tool, and the European Union, Indian government, Korean government, and Taiwanese government as a cancer monitoring or cancer screening test. Onko?Sure test kits are currently sold as a blood test for cancer in Europe, India, Taiwan, Korea, and Vietnam and in Chili for research use.

About Radient Pharmaceuticals:
Headquartered in Tustin, California, Radient Pharmaceuticals is dedicated to saving lives and money for patients and global healthcare systems through the deployment of its FDA-cleared In Vitro Diagnostic Onko-Sure® Test Kits for colon-rectal cancer recurrence monitoring The company’s focus is on the discovery, development and commercialization of unique high-value diagnostic tests that help physicians answer important clinical questions related to early disease-state detection, treatment strategy and the monitoring of disease progression or recurrence. To learn more about our company, people and potentially life-saving cancer test, visit.

Forward-Looking Statements:
Safe Harbor Statement under the Private Securities Litigation Reform Act of 1995: The statements contained in this document include certain predictions and projections that may be considered forward-looking statements under securities law. These statements involve a number of important risks and uncertainties that could cause actual results to differ materially including, but not limited to, the performance of joint venture partners, as well as other economic, competitive and technological factors involving the Company’s operations, markets, services, products, and prices. With respect to Radient Pharmaceuticals Corporation, except for the historical information contained herein, the matters discussed in this document are forward-looking statements involving risks and uncertainties that could cause actual results to differ materially from those in such forward-looking statements.

RPC Contact:
Kristine Szarkowitz
Director-Investor Relations
Email Contact
Tel: 206.310.5323

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Filed Under: Prescription Drugs and Pharmacy, Public Health and Research

Two Atlanta Business Leaders Appointed to Board of India-US Business Network

Posted on December 7, 2010 Written by Editor

SOURCE: Morley Research

ATLANTA, GA–(Marketwire – December 7, 2010) – Jane Green, PhD, president of Morley Research Consortium, and Donald Johnson, Chief Operations Officer of Opus Institutional Review Board, have been appointed to the India-US Business Network (IUSBN) Board of Directors.

In this capacity Dr. Green and Mr. Johnson will be integral to shaping the relationship between India and the United States as the two countries explore and develop mutually beneficial opportunities. The initial four areas of interest for the IUSBN are Biotech, Pharma, Diagnostic, Devices and Health Care; Cold Chain; Education; and Renewable Energy. 

The two Atlanta leaders, who both have extensive experience in clinical research, have been asked to sit on the Biotech Committee for the IUSBN. This committee is focused on matching companies from each country with counterparts in research and development.

“This is both an honor and an opportunity,” said Dr. Green. “By furthering cooperation with India, we achieve the ability to improve the level of research and development in the area of biotech in both countries. I believe this exchange of ideas and information can create exponential advances in developing products and technologies that will benefit the entire world.”

Dr. Green’s organization, the Morley Research Consortium, assists device and drug companies to achieve their research goals of bringing a new product to market through its contract research organization which additionally provides research compliance, total trial management, contracting, site identification and training.

“India is a world leader in technology innovations, and expects to achieve similar success in the biotech field,” said Mr. Johnson. “I am pleased to be able to play a role in helping reach that goal, while also strengthening and benefiting U.S. companies.”

Mr. Johnson manages Opus Institutional Review Board (IRB), the ethical overview organization mandated to review clinical research studies worldwide. Opus IRB has a board of directors consisting of the country’s top practicing physicians in a variety of clinical specialties and encompasses over 20 medical disciplines.

Mr. Johnson and Dr. Green are the first two board members of the IUSBN from the southern region of the U.S. and they are planning the initial Atlanta area meeting of the IUSBN in the first quarter 2011 for others interested in the organization.

Learn more about IUSBN at www.iusbn.org. 

Media Contact:
Lynn Hood
Email Contact
678-427-5040

Company Contact:
Jane Green
Email Contact
404-625-0036

Filed Under: Healthcare Business, Public Health and Research

ICare4autism to Create World’s First Global Autism Research and Education Center

Posted on December 7, 2010 Written by Editor

SOURCE: ICare4autism

Mayor of Jerusalem Pledges Support in City Hall Ceremony

NEW YORK, NY and JERUSALEM–(Marketwire – December 7, 2010) – The International Center for Autism Research and Education (ICare4autism), a New York-based charity, announced plans to create the world’s first Global Autism Center on Mt. Scopus in Israel, dedicated to catalyzing breakthrough innovation in autism research and treatment. In a ceremony at Jerusalem‘s City Hall hosted by Mayor Nir Barkat, ICare4autism’s President Joshua Weinstein signed an agreement paving the way for ICare4autism to acquire the campus of Bezalel Academy of Art in 2013, and convert it into a center, housing:

  • State-of-the-art autism research facilities to serve as a platform for global collaboration.

  • The world’s first university-level school of autism studies, to raise therapeutic standards worldwide.

  • A model school, applying the latest research, technology and design to the needs of students across the Autistic Spectrum.

  • A foundation to support transformative global collaborations in autism education and treatment.

Joshua Weinstein said, “To tackle the global autism epidemic, we need a community of researchers, educators and advocates that reaches across borders. Our new Center will give us the ability to convene and empower that community.”

Said Dr. Eric Hollander, Chairman of ICare4autism’s Scientific Advisory Council, “The Center will drive the research needed to discover the etiology of autism, ultimately leading to better methods of detection and treatment.”

Said Mayor Barkat, “We welcome ICare4autism’s plan to create a Global Autism Center on Mt. Scopus, and we look forward to the breakthroughs in research that will emanate from its campus to benefit the entire world.”

About Joshua Weinstein, MBA and MA Ed
Mr. Weinstein is the Founder of ICare4autism, which encompasses Shema Kolainu – Hear our Voices School and Center for Children with Autism in New York City, and Tishma – ABA School and Center for Children with Autism in Jerusalem, Israel.

About Dr. Eric Hollander, MD
Dr. Hollander, Chairman of the Advisory Council of ICare4autism, is a renowned psychiatrist on the faculty of Montefiore Medical Center University Hospital of Albert Einstein College of Medicine, former Chair of Psychiatry at the Mt. Sinai School of Medicine and Director of the Seaver and Greater New York Autism Center of Excellence.

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Filed Under: Public Health and Research

Santa’s on His Way… Santa Claus Isn’t Just Bringing Toys This Holiday Season, He’s Also Bringing Happiness to Kids and Families That Are Stricken…

Posted on December 7, 2010 Written by Editor

SOURCE: Hair Fairies

LOS ANGELES, CA–(Marketwire – December 7, 2010) – Announced today, Santa Claus and some very special helpers will be visiting Hair Fairies salons (www.hairfairies.com) nationwide. Santa will be on site every Saturday in December through Christmas to deliver cheer, take photos, listen to wish lists and hand out special treats. The holiday season is upon us and nobody wants it ruined by having to deal with head lice. So, if these bugs happen to find their way into your home, what better way to get rid of them then at one of Hair Fairies unique salons, with the added benefit of meeting jolly ol’ St. Nick. The friendly technicians will work their magic with special techniques and 100% natural, non-toxic products. They will also be discounting many of their all natural Nit-Zapping™ head lice treatment products and up to 50% off your final treatment.

“The holiday season is an important time of year and we want families to be able to enjoy it the best way possible with fun, laughter, and free of lice!” stated Maria Botham, Founder and President of the Hair Fairies brand. “This is also a fun way to give back to the community.”

Hair Fairies, The Head Lice Helpers, the country’s leading head lice brand, has been helping millions of families that are stricken with head lice since 1999. To learn more about Hair Fairies salons and locations, their natural products and to order online, visit www.hairfairies.com. Even if you do not have head lice stop by and visit Santa and learn how you can prevent an outbreak in the future! 

HoHoHo… Happy Holidays from the Hair Fairies staff. 

For more information on the festivities you can
contact one of their salons at their toll free number,
Hair Fairies
1-877-285-0069

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Filed Under: Public Health and Research

Des chefs de file favorisent la création d’un registre national d’immunisation

Posted on December 6, 2010 Written by Editor

OTTAWA, ONTARIO–(Marketwire – 6 déc. 2010) – Alors que le Canada songe au renouvellement de son Accord sur les soins de santé en 2014, les principaux intervenants en santé publique sont optimistes quant à la mise sur pied d’un registre national d’immunisation, déclare Debra Lynkowski, présidente-directrice générale de l’Association canadienne de santé publique (ACSP).

« Notre réponse typiquement canadienne aux problèmes d’immunisation plus vastes a malheureusement entraîné des approches diverses au pays », affirme Debra Lynkowski. « Maintenant, alors qu’on approche du renouvellement de l’Accord sur les soins de santé, en 2014, le moment est venu de mettre sur pied un registre national d’immunisation harmonisé. »

Nous reconnaissons qu’une demande de financement supplémentaire auprès des gouvernements peut sembler invraisemblable dans le présent contexte fiscal, mais une stratégie nationale d’immunisation basée sur un registre national, soutenu par toutes les provinces et les territoires, assurerait une protection équitable des Canadiens contre les maladies évitables par la vaccination, et ce, peu importe leur lieu de résidence, leur âge ou leur statut socio-économique.

« Tous les Canadiens devraient avoir un accès égal à l’immunisation contre les maladies évitables par la vaccination. Le lieu de résidence ne devrait pas avoir d’incidence quant à l’accès aux programmes d’immunisation », soutient Debra Lynkowski.

Les améliorations découlant d’une stratégie nationale d’immunisation comprendraient une harmonisation des calendriers de vaccination pour les enfants partout au pays, un alignement de l’introduction des nouveaux vaccins et une égalité d’accès aux vaccins dans toutes les provinces et territoires. La collecte méthodique de données relatives à l’immunisation dans un registre national d’immunisation modernisera la façon dont les autorités transmettent les dossiers d’immunisation des patients et aidera à assurer des taux de couverture suffisamment élevés partout au pays afin de mieux protéger les Canadiens.

Debra Lynkowski souligne qu’une stratégie nationale promouvrait aussi de meilleures possibilités de recherche, la promotion de vaccins, ainsi qu’une meilleure éducation des fournisseurs de soins de santé et du public. À l’heure actuelle, le Canada n’a pas de calendrier harmonisé de vaccination systématique pancanadienne.

« En bref, il vaut mieux prévenir les maladies que d’avoir à les traiter », conclut Debra Lynkowski.

Ces recommandations sont le résultat d’un dialogue continu sans précédent que tiennent les dirigeants du gouvernement et les principaux intervenants de l’industrie et des secteurs de la santé publique et des soins de santé.

Fondée en 1910, l’Association canadienne de santé publique (ACSP) est le porte-parole de la santé publique au Canada. L’indépendance de l’ACSP, ses liens avec la communauté internationale et le fait qu’elle soit la seule organisation non gouvernementale canadienne à se consacrer exclusivement à la santé publique la placent en position idéale pour conseiller les décideurs à propos de la réforme du réseau de santé publique et pour orienter les initiatives visant à protéger la santé individuelle et collective au Canada et dans le monde. Grâce à son effectif diversifié représentant plus de 25 professions, son efficacité démontrée, son approche de collaboration et son envergure nationale, l’ACSP est le chef de file canadien en santé publique. 

Contexte

L’ACSP travaille activement avec les principaux intervenants de l’industrie pour créer un contexte favorable à une stratégie nationale d’immunisation qui protégerait les Canadiens contre les maladies évitables par la vaccination. Pour faciliter un dialogue continu, l’ACSP a organisé une table ronde en 2009 avec les principaux intervenants et a depuis participé à diverses activités d’échange d’information organisées par d’importants organismes nationaux. 

En outre, pour assurer une réponse dans les meilleurs délais à la pandémie H1N1 de l’année dernière, l’ACSP, en collaboration avec l’Agence de la santé publique du Canada, l’Association médicale canadienne, le Collège des médecins de famille du Canada et la Société nationale de spécialistes pour la médecine communautaire, a mis au point l’outil « GRIPPE PANDÉMIQUE H1N1 — Aide-mémoire à l’intention des cliniciens de première ligne ».

En réponse à l’importante demande de renseignements en plus des renseignements déjà offerts par le gouvernement du Canada, l’ACSP a fondé des centres d’échange d’information canadiens sur la grippe H1N1 comme autre source non gouvernementale de renseignements fiables pour les Canadiens.

En tant que secrétariat pour la Coalition canadienne pour la sensibilisation et la promotion de la vaccination, l’ACSP fait office de facilitateur et de coordonnateur d’activités de la Coalition pour réduire au minimum les chevauchements et s’assurer que les Canadiens reçoivent des messages cohérents concernant l’immunisation.

Un document d’information est disponible à l’adresse suivante : http://media3.marketwire.com/docs/cpha-fre.pdf

Filed Under: Public Health and Research

Leaders Build Momentum for Creation of National Immunization Registry

Posted on December 6, 2010 Written by Editor

OTTAWA, ONTARIO–(Marketwire – Dec. 6, 2010) – As Canada looks to the renewal of its Health Accord in 2014, public health leaders are hopeful room can be found for the creation of a national immunization registry, says Debra Lynkowski, Chief Executive Officer, Canadian Public Health Association (CPHA).

“Unfortunately, our typically Canadian response to broader immunization issues has resulted in a patchwork of approaches across the country,” said Lynkowski. “Now, as we approach the renewal of the Health Accord in 2014, is the time for a harmonized, national immunization registry.”

While we recognize additional funding may seem an improbable request of governments in the current fiscal environment, a national immunization strategy that includes at its core a national registry, one supported by all provinces and territories, would ensure Canadians are equitably protected against vaccine-preventable illnesses, regardless of where they live, their age or their socio-economic status.

“All Canadians should have equal access to immunizations for vaccine-preventable diseases. Where you live should have no bearing on access to immunization programs,” said Lynkowski.

Improvements stemming from a national immunization strategy would include harmonization of childhood immunization schedules across the country, aligned introduction of new vaccines, and equal access to vaccines across all provinces and territories. The systematic collection of immunization data in a national immunization registry will modernize the way jurisdictions communicate patients’ immunization histories and help to ensure coverage rates are high enough throughout the country to best protect Canadians.

A national strategy would also promote better opportunities for research, vaccine promotion and improved education of health care providers and the general public, said Lynkowski. Currently, Canada lacks a harmonized cross-country routine immunization schedule.

“Simply put, it is better to prevent disease and illness than to have to treat it,” said Lynkowski.

These recommendations are a result of unprecedented and ongoing dialogue with government leaders, industry and public health and health care stakeholders.

Founded in 1910, the Canadian Public Health Association (CPHA) is the independent voice for public health in Canada with links to the international community. As the only Canadian non-governmental organization focused exclusively on public health, CPHA is uniquely positioned to advise decision-makers about public health system reform and to guide initiatives to help safeguard the personal and community health of Canadians and people around the world. With a diverse membership representing more than 25 professions, a track record of success, a collaborative approach and national reach, CPHA is Canada’s Public Health Leader.

Background

CPHA has been working actively with stakeholders to improve the environment for a national immunization strategy that would protect Canadians against vaccine preventable diseases. To facilitate an ongoing dialogue, CPHA organized a roundtable discussion in 2009 with stakeholders and has since participated in various information-sharing activities organized by leading national organizations.

In addition, to ensure timely response to last year’s H1N1 pandemic, the CPHA, in collaboration with the Public Health Agency of Canada, the Canadian Medical Association, College of Family Physicians of Canada and the National Specialty Society for Community Medicine developed “PANDEMIC H1N1: Fast facts for front-line clinicians.”

In response to a significant demand for information in addition to what was available from the Government of Canada, CPHA established the Canadian H1N1 Information Clearinghouse as an additional, non-governmental source of reliable information for Canadians.

As secretariat for the Canadian Coalition for Immunization Awareness and Promotion, CPHA facilitates and coordinates the activities of the Coalition to minimize duplication and ensure that Canadians receive consistent immunization messages.

A backgrounder is available at the following address: http://media3.marketwire.com/docs/cpha-eng.pdf

Filed Under: Prescription Drugs and Pharmacy, Public Health and Research

Shuangshi AHP Co. (HIRU) Expands Sales Area

Posted on December 3, 2010 Written by Editor

NANCHANG, CHINA–(Marketwire – Dec. 3, 2010) – Hiru Corporation (PINK SHEETS:HIRU) (www.hirucorporation.com) subsidiary Shuangshi AHP Co. dispatched company representatives to evaluate the agricultural developments and increase company sales in the regions of Ganzhou, Yichun and Jian.

Shuangshi’s assistant general manager and sales manager met with several potential customers in the aforementioned regions to discuss the potential of Shuangshi products on the local markets, as the company works on gaining more exposure with Chinese farmers for their vaccination needs.

The representatives also negotiated with two new agricultural clients, each client reporting annual sales of approximately $30 million USD. Following these negotiations, Shuangshi AHP representatives supplied the customers with new HIRU products for testing and evaluation by the clients. Shuangshi AHP anticipates to gain more new clients as the company’s top quality animal vaccination products gain exposure in the market.

Safe Harbor Statement

Information in this news release may contain statements about future expectations, plans, prospects or performance of Hiru Corporation that constitute forward-looking statements for purposes of the Safe Harbor Provisions under the Private Securities Litigation Reform Act of 1995. The words or phrases “can be,” “expects,” “may affect,” “believed,” “estimate,” “project” and similar words and phrases are intended to identify such forward-looking statements. Hiru Corporation cautions you that any forward-looking information provided by or on behalf Hiru Corporation is not a guarantee of future performance. None of the information in this press release constitutes or is intended as an offer to sell securities or investment advice of any kind. Hiru Corporation’s actual results may differ materially from those anticipated in such forward-looking statements as a result of various important factors, some of which are beyond Hiru Corporation’s control. In addition to those discussed in Hiru Corporation’s press releases, public filings, and statements by Hiru Corporation’s management, including, but not limited to, Hiru Corporation’s estimate of the sufficiency of its existing capital resources, Hiru Corporation’s ability to raise additional capital to fund future operations, Hiru Corporation’s ability to repay its existing indebtedness, the uncertainties involved in estimating market opportunities, and in identifying contracts which match Hiru Corporation’s capability to be awarded contracts. All such forward-looking statements are current only as of the date on which such statements were made. Hiru Corporation does not undertake any obligation to publicly update any forward-looking statement to reflect events or circumstances after the date on which any such statement is made or to reflect the occurrence of unanticipated events.

Filed Under: Public Health and Research

TomoTherapy Sponsors American Cancer Society’s Fall 2010 Matching Grant Challenge

Posted on December 1, 2010 Written by Editor

SOURCE: TomoTherapy

TomoTherapy to Match up to $100,000 in Donations by Dec. 15

MADISON, WI–(Marketwire – December 1, 2010) –  TomoTherapy Incorporated (NASDAQ: TOMO), maker of advanced radiation therapy solutions for the treatment of cancer and other diseases, today announced that it is the exclusive sponsor of the American Cancer Society’s Fall 2010 Matching Grant Challenge, a national fundraising campaign that was launched in November.

As sponsor, TomoTherapy will contribute $1 for every $1 donated by the general public, up to $100,000, to support the American Cancer Society’s efforts to help people stay well and get well from cancer, find cures, and fight back against the disease. The Matching Grant Challenge ends on December 15, 2010.

“Every day, TomoTherapy’s innovative radiation therapy solution helps patients fight cancer. With our support of the American Cancer Society, we extend our impact beyond technology,” said Fred Robertson, M.D., TomoTherapy’s CEO. “In matching the generous contributions of individuals, TomoTherapy proudly strengthens the efforts of the American Cancer Society — from funding groundbreaking research to providing resources for patients, their families and caregivers at every step in the cancer experience.”

About TomoTherapy Incorporated
TomoTherapy Incorporated develops, markets and sells advanced radiation therapy solutions that can be used to treat a wide variety of cancers, from the most common to the most complex. The ring gantry-based TomoTherapy® platform combines integrated CT imaging with conformal radiation therapy to deliver sophisticated radiation treatments with speed and precision while reducing radiation exposure to surrounding healthy tissue. TomoTherapy’s suite of solutions include its flagship Hi·Art® treatment system, which has been used to deliver more than three million CT-guided, helical intensity-modulated radiation therapy (IMRT) treatment fractions; the TomoHD™ treatment system, designed to enable cancer centers to treat a broader patient population with a single device; and the TomoMobile™ relocatable radiation therapy solution, designed to improve access and availability of state-of-the-art cancer care. TomoTherapy’s stock is traded on the NASDAQ Global Select Market under the symbol TOMO. To learn more about TomoTherapy, please visit TomoTherapy.com.

©2010 TomoTherapy Incorporated. All rights reserved. TomoTherapy, Tomo, TomoDirect, TQA, the TomoTherapy logo and Hi·Art are among trademarks, service marks or registered trademarks of TomoTherapy Incorporated in the United States and other countries.

Media Contacts:
Kevin O’Malley
Manager, Corporate Communications
608.824.3384
Email Contact

Susan Lehman
Rockpoint Public Relations
510.832.6006
Email Contact

Filed Under: Public Health and Research

Taconic Facility in Cologne, Germany Receives AAALAC Accreditation

Posted on December 1, 2010 Written by Editor

SOURCE: Taconic

All Taconic Programs Worldwide Now Have Voluntary Accreditation

HUDSON, NY–(Marketwire – December 1, 2010) – Taconic, a leading provider of in vivo solutions to life science researchers worldwide, announced that its Cologne, Germany production program has earned accreditation from AAALAC International (the Association for Assessment and Accreditation of Laboratory Animal Care International). With this accreditation, all Taconic programs worldwide are now AAALAC accredited thereby assuring customers that Taconic meets the highest industry standard of quality, health, genetic integrity and care for its animal models.

AAALAC International promotes the humane treatment of animals in science through voluntary accreditation and evaluation programs. Taconic was one of the first suppliers to be accredited by AAALAC International in 1969.

“For more than four decades, through our voluntary participation in the AAALAC accreditation process, Taconic has demonstrated its commitment to the safe, humane treatment of the research animals that are vital to our clients’ biomedical research,” said Jeffrey J. Lohmiller, DVM, MS, ACLAM, Global Senior Director, Veterinary Sciences, Taconic. “Attaining AAALAC accreditation across all of our programs worldwide is an achievement that reflects Taconic’s unwavering focus on quality and accountability.” 

The rigorous accreditation process required both a stringent internal review by Taconic and a comprehensive, on-site assessment by AAALAC evaluators, reviewing the Cologne site’s entire animal care and use program. To maintain their accredited status, all Taconic programs undergo re-evaluation every three years as per AAALAC requirements.

According to AAALAC International, more than 800 companies, universities, hospitals, government agencies and other research institutions have earned this prestigious accreditation.

About Taconic
Taconic is a leading provider of life sciences solutions to researchers worldwide, offering innovative lab animal models and scientific services that facilitate in vivo studies and advance drug discovery. Taconic’s wide range of advanced solutions include custom genetically modified rat and mouse model generation and production, contract breeding, off-the-shelf model repositories, compound profiling, contract research, imaging, genetic monitoring and health testing. Headquartered in New York’s Hudson River Valley, Taconic operates seven breeding facilities and three service laboratories in the U.S. and Europe and maintains a staff of over 1,000 scientific specialists committed to technological innovation. Additional information about Taconic is available at www.taconic.com.

For Taconic media inquiries:
Susan Fogt
Marketing Communications
518.697.3962
[email protected]

Filed Under: Public Health and Research

LumaMed Adds Cancer Imaging Technology From the Wellman Center for Photomedicine

Posted on December 1, 2010 Written by Editor

SOURCE: LumaMed

New Technology Could Revolutionize Cancer Surgery

ATLANTA, GA and BOSTON, MA–(Marketwire – December 1, 2010) – LumaMed LLC has entered into an initial agreement with Massachusetts General Hospital to commercialize an imaging system developed at the Wellman Center for Photomedicine that could revolutionize cancer surgery.

The technology is complementary to that previously licensed by LumaMed from Providence Hospital in Oregon for teledermatology imaging, and has the demonstrated ability to provide real-time surgical guidance, enabling a surgeon to “see” cancer margins.

LumaMed’s cancer imaging technology addresses an estimated $1 billion market opportunity for products that improve efficiency and efficacy in cancer removal procedures. Cancer margin delineation is critical in instances where tissue preservation is important, including skin, head and neck, breast, prostate and brain surgeries.

LumaMed is initially focusing on skin cancer, which is the most common of all cancers. Each year, over one million new cases of skin cancer are detected and many require painstaking and expensive Mohs surgery. Once cleared by the FDA, LumaMed plans to market the new devices to Mohs skin cancer surgeons as a visual aid to help eliminate the need for more than one surgical stage, thus improving patient care and creating a substantial economic benefit.

“In combination with a trained physician, we believe LumaMed’s technology could complement histopathological evaluation, help accurately define margins and reduce the occurrence of biopsies,” said Mark A. Samuels, chief executive officer of LumaMed. “The technology agreement with Massachusetts General Hospital will provide us with the additional tools necessary for development and commercialization of our image-guided surgical systems for the real-time evaluation of skin lesions and other cancers.”

LumaMed is combining two powerful approaches for rapid, easy and cost-effective onsite and remote evaluation of suspicious skin lesions using polarization-based spectroscopic imaging technology. Called “Polarization Subtraction Imaging,” PsiScan technology selectively samples the dermal/epidermal junction and papillary dermis, where cancer originates, and enhances image clarity by rejecting surface scatter and light from deeper layers. This results in images with significantly greater clarity and contrast for improved tumor identification and margin delineation. Clarity and contrast is required in skin cancer evaluation to recognize the disruption of the rich texture of the papillary dermis or to detect tumor silhouettes that identify basal cell carcinomas. Such disruption is difficult to discern with existing dermatoscopes or point-and-shoot digital cameras.

About LumaMed, LLC.
LumaMed is developing devices that provide rapid, easy and improved imaging of cancer based on patented “Polarization Subtraction Imaging” (PSI) technology. LumaMed’s revolutionary cancer visualization tools enable real-time imaging of cancer margins during surgery with an accuracy approaching that of conventional pathology. In addition to the initial focus on skin cancer, the approach can be used with other cancers such as prostate, breast, and head and neck cancers. LumaMed products have not been cleared by the FDA for sales in the U.S. and are not presently being offered for sale. For more information, visit www.lumamed.com.

Company contact:
Anju Mathew
VP, Business Development
Email Contact
877-438-5539, ext 105

PR contact:
Lynn Hood
Email Contact
678-974-2623

Filed Under: Public Health and Research, Senior Care

MMRGlobal Settles With Lymphoma Research Foundation

Posted on November 30, 2010 Written by Editor

SOURCE: MMRGlobal, Inc.

LOS ANGELES, CA–(Marketwire – November 30, 2010) – MMRGlobal, Inc. (OTCBB: MMRF) (MMR) today announced it has signed a settlement agreement with the Lymphoma Research Foundation (LRF), resolving its lawsuit with LRF and giving the Company exclusive control of certain data and tissue samples created during trials of Favrille, Inc.’s FavId™ vaccine. The assets had been the subject of an ownership dispute with LRF. The Company acquired the FavId intellectual property, along with other biotech assets, from its reverse merger with Favrille, Inc., a San Diego biotech company, in January 2009. More than $140 million was spent on the development of the vaccine and other biotech assets and related patents. 

According to Kathleen M. Smith, a principal at Translational Medicine Consulting and a biorepository expert who provided expert testimony in the MMR litigation with LRF, the tissue samples could have values substantially in excess of one million dollars per set. When combined with clinical data and associated intellectual property belonging to MMR, the values could be significantly greater. 

“We will continue to explore licensing opportunities for these biotech assets, patents and other intellectual property with pharmaceutical companies, universities and institutional investors to create future streams of revenue for our shareholders,” said Robert H. Lorsch, MMRGlobal CEO. “I look forward to these assets being put to use to help find additional treatments for Non-Hodgkin’s Lymphoma and other related diseases while generating licensing revenues to help finance the Company’s primary business, namely the development and distribution of its MyMedicalRecords Personal Health Record and MMRPro Electronic Health Record products and services.”

MMR contended that prior to the merger, portions of the Company’s intellectual property were transferred by previous employees and or consultants of Favrille to third parties, including Lymphoma Research Foundation, without the knowledge and consent of Favrille’s Board of Directors or Science Committee. After MMR learned of the transfer, the Company pursued LRF to regain control of the data and tissue samples on behalf of its shareholders.

As part of the settlement agreement, the Lymphoma Research Foundation also settled a complaint filed in Los Angeles Superior Court by The RHL Group, Inc., a creditor of MMRGlobal, against LRF and others involving the transfer of the data, tissue samples and other assets which previously were the property of Favrille. Although The RHL Group case against LRF is settled, the case against the other named defendants is still active.

Over the last two years, MMRGlobal has been working to maximize the value of its biotech assets by perfecting its worldwide patent portfolio, regaining control of its anti-CD20 antibodies and FavId intellectual property including tissue samples, and developing licensing opportunities for the data and materials for use in Non-Hodgkin’s Lymphoma, target validation and other therapeutic research. As part of the settlement agreement, MMRGlobal shall cause the assets or portions of them to be used in further medical research.

About MMRGlobal, Inc.

MMRGlobal, Inc., through its wholly-owned operating subsidiary, MyMedicalRecords, Inc. (“MMR”), provides secure and easy-to-use online Personal Health Records (“PHRs”) and electronic safe deposit box storage solutions, serving consumers, healthcare professionals, employers, insurance companies, financial institutions, and professional organizations and affinity groups. MyMedicalRecords enables individuals and families to access their medical records and other important documents, such as birth certificates, passports, insurance policies and wills, anytime from anywhere using the Internet. The MyMedicalRecords Personal Health Record is built on proprietary, patented technologies to allow documents, images and voicemail messages to be transmitted and stored in the system using a variety of methods, including fax, phone, or file upload without relying on any specific electronic medical record platform to populate a user’s account. The Company’s professional offering, MMRPro, is designed to give physicians’ offices an easy and cost-effective solution to digitizing paper-based medical records and sharing them with patients in real time through an integrated patient portal. MMR is an Independent Software Vendor Partner with Kodak to deliver an integrated turnkey EMR solution for healthcare professionals. MMR is also an integrated service provider on Google Health. To learn more about MMRGlobal, Inc. and its products, visit www.mmrglobal.com.

Forward-Looking Statements

Statements in this press release that are not strictly historical in nature constitute “forward-looking statements.” Such statements include, but are not limited to, statements regarding MMRGlobal, Inc.’s assets including but not limited to its primary Health IT businesses, samples and data from vaccine and clinical trials, and anti-CD20 antibody assets. Such forward-looking statements involve known and unknown risks, uncertainties and other factors that may cause actual results to be materially different from historical results or from any results expressed or implied by such forward-looking statements. These factors include, but are not limited to, risks and uncertainties related but not limited to changes in MMRGlobal, Inc.’s business prospects, its results of operations or financial condition, government regulation and changes in healthcare initiatives, developing and defending its intellectual property rights including those pertaining to the Company’s biotechnology assets, the development and approval of biotechnology/biopharmaceutical product candidates and Health IT products and such other additional risks and uncertainties discussed in the Company’s filings with the Securities and Exchange Commission. All subsequent written and oral forward-looking statements attributable to the Company (or any person acting on the Company’s behalf) are qualified by the cautionary statements in this notice. MMRGlobal, Inc. is providing this information as of the date of this release and, except as required by law, does not undertake any obligation to update any forward-looking statements contained in this release as a result of new information.

CONTACT:

Michael Selsman
Public Communications Co.
(310) 553-5732
[email protected]

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Filed Under: Healthcare Business, Public Health and Research

International Alzheimer’s Researcher and Inventor to Speak at Quietmind Foundation

Posted on November 29, 2010 Written by Editor

SOURCE: Quietmind Foundation

Quietmind Foundation: Promoting Research of Drug-Free, Noninvasive Treatments for Brain Disorders and Trauma

PLYMOUTH MEETING, PA–(Marketwire – November 29, 2010) – In advance of the first randomized, placebo-controlled clinical trial in the world of its type for Alzheimer’s disease and other dementias, Quietmind Foundation (QMF), Plymouth Meeting, Pa., is honored to host two presentations by Gordon Dougal, M.D., a National Health Service physician, inventor, and dementia researcher from Durham, U.K. Dr. Dougal will discuss the application of 1072nm infrared light therapy in the treatment of dementia. The presentations will include the pioneering research findings from studies conducted by Dr. Dougal’s colleagues at Durham University on the effects of this type of phototherapy on neuroprotection and beta amyloid plaque deposition and abeta42 oligomer levels.

Professional colleagues, caregivers, and family members of people struggling with neurodegenerative disorders are cordially invited. The free programs will take place on Sunday, December 12, from 4:00 p.m. to 5:30 p.m., and Monday, December 13, from 11:30 a.m. to 1:00 p.m., at the QMF offices, 521 Plymouth Rd., Suite 111, Plymouth Meeting, Pa., 19462. Light refreshments will be served.

Each program will begin with a brief scientific overview by Dr. Dougal directed toward professionals working in research and clinical care of people struggling with dementia. Marvin Berman, Ph.D., QMF’s president, will then discuss the foundation’s previous research in dementia and current clinical work. Following will be a demonstration of the 1072nm infrared light therapy and overview of parameters of the clinical trial to be conducted at the QMF offices.

For a fuller description of the upcoming clinical trial utilizing the 1072nm technology for the treatment of early stage dementia: http://clinicaltrials.gov/ct2/show/NCT01059877?term=1072&rank=3

About Quietmind Foundation

Quietmind Foundation, a 501(c)3 nonprofit founded in 2000, is an international center for cutting-edge research and consultation in the use of brainwave (EEG) biofeedback and related technologies. Its ongoing research agenda — and the nondrug, noninvasive treatments offered through its affiliate, Quietmind Associates — focuses on the spectrum of neurodegenerative disorders, including dementia, Parkinson’s, ALS, and MS as well as traumatic brain injury, PTSD, and learning disabilities. Its goal is to integrate innovative technologies and evidence-based behavioral interventions into governmental, public health, and educational service delivery systems.

QMF’s prior research on Alzheimer’s disease was accepted for presentation at the July 2009 International Conference on Alzheimer’s Disease (ICAD) in Vienna, Austria. This research demonstrated improvements in subjects’ memory, executive function, and psychiatric symptoms, and a reduction in medications.

For further information and reservations for either presentation: 610-940-0488 or [email protected]

Press Contact:

For more information, contact:
Marvin H. Berman, Ph.D., CBT, BCN
Principal, Quietmind Associates
President, Quietmind Foundation
Psychotherapy, Assessment, Neurofeedback, Consultation,
and Applied Clinical Research
521 Plymouth Road, Suite 111
Plymouth Meeting PA 19462
T: 610-940-0488
F: 215-359-0630
E: Email Contact

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Filed Under: Public Health and Research

Type 1 Diabetes Mortality Rates Dropping

Posted on November 26, 2010 Written by Editor

SOURCE: American Diabetes Association

Concerns Remain for Women, African Americans

ALEXANDRIA, VA–(Marketwire – November 26, 2010) – Mortality rates for people with type 1 diabetes are decreasing, but overall remain seven times higher than those of the general population — likely as a result of long-term complications, a study in the December issue of Diabetes Care reports.

And while there were no significant differences in mortality rates between genders, women with type 1 diabetes were 13 times more likely to die than women who did not have diabetes, reported researchers from the University of Pittsburgh. Also in this study, part of the Epidemiology Research International Study Group, a much higher proportion of African Americans (50.6 percent) died than Caucasians (24 percent).

“It’s unclear why, for both women and African Americans, type 1 diabetes has such a major effect compared to the general population,” said Dr. Trevor Orchard, senior author of the study. “This greater effect of diabetes for women is not seen as strongly in studies in other parts of the world. One thing that is clear is that we need to pay special attention to their care and treatment and continue to investigate why they might be disproportionately impacted by the long-term consequences of this disease.”

Overall, mortality rates for people with type 1 diabetes fell significantly in this community-based population from Allegheny County, PA, over the past several decades, the study found. For those diagnosed between 1965 and 1969, mortality rates were 9.3 times higher than the general population. However, for those most recently diagnosed (1975-1979), the rate was just 5.6 times higher, showing a clear decline.

“It looks like the main improvement in those most recently diagnosed is related to dramatically reducing mortality in the first five years after diagnosis,” said Dr. Aaron Secrest, lead author of the paper. “We think it’s probably a result of better management and awareness of diabetes control, leading to providers and patients doing a better job of monitoring for acute complications.”

Overall, reductions in mortality are most likely due to the tremendous improvements in treatment and care during the 1980s and 1990s, the researchers noted. In particular, blood glucose self-monitoring, A1C testing and use of new blood pressure medications such as angiotensin-converting enzyme inhibitors, which also help protect against diabetic kidney disease. These changes have greatly improved both blood sugar and blood pressure control, often the cause of life-threatening complications.

The study looked at people in Allegheny County the Pittsburgh area who had type 1 diabetes diagnosed as a child between 1965 and 1979 and at the time of analysis had a duration of diabetes between 28 and 43 years, and explored differences in mortality based on sex, race (Caucasian vs. African American) and year of diagnosis.

For more information, please contact Dr. Trevor J. Orchard, University of Pittsburgh, Department of Epidemiology, Graduate School of Public Health, at email: [email protected] or call 412-383-1032.
To contact Dr. Aaron Secrest call 940-597-1991.

Diabetes Care, published by the American Diabetes Association, is the leading peer-reviewed journal of clinical research into one of the nation’s leading causes of death by disease. Diabetes also is a leading cause of heart disease and stroke, as well as the leading cause of adult blindness, kidney failure, and non-traumatic amputations.

The American Diabetes Association is leading the fight to stop diabetes and its deadly consequences and fighting for those affected by diabetes. The Association funds research to prevent, cure and manage diabetes; delivers services to hundreds of communities; provides objective and credible information; and gives voice to those denied their rights because of diabetes. Founded in 1940, our mission is to prevent and cure diabetes and to improve the lives of all people affected by diabetes. For more information please call the American Diabetes Association at 1-800-DIABETES (1-800-342-2383) or visit www.diabetes.org. Information from both these sources is available in English and Spanish.

Contact:
Dayle Kern
American Diabetes Association
(703) 549-1500 ext. 2290

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Filed Under: Public Health and Research

TomoTherapy and NELCO Partner to Reduce Radiation Therapy Construction Costs

Posted on November 23, 2010 Written by Editor

SOURCE: TomoTherapy

Total ShieldTM for TomoTherapy® Cuts Costs, Time Associated With Renovation of Treatment Vaults

MADISON, WI–(Marketwire – November 23, 2010) – TomoTherapy Incorporated (NASDAQ: TOMO), maker of advanced radiation therapy solutions for the treatment of cancer and other diseases, today announced availability of a shielding solution that enables hospitals and cancer centers to quickly, easily and inexpensively build out treatment vaults that are properly shielded for use of the TomoTherapy® radiation therapy system. The Total Shield™ by NELCO, the worldwide leader in designing, manufacturing, and installing specialized products and services for the medical, industrial, and construction fields, is a customized shielding enclosure designed to fit around a TomoTherapy unit, making it possible for the radiation therapy system to be placed into existing under-shielded vaults or other treatment rooms where there may not be enough space to install necessary shielding using the existing infrastructure.

Total Shield provides hospitals and cancer centers with the flexibility to put the TomoTherapy system in an existing space, which may be too small or may not include enough shielding for modern intensity-modulated radiation therapy (IMRT) devices. Instead of adding shielding in the walls, the Total Shield enclosure is designed to wrap around the TomoTherapy system itself.

By taking this approach, TomoTherapy customers can potentially save hundreds of thousands of dollars in shielding costs and eliminate the months it takes to install conventional shielding solutions. Total Shield can be installed in just a matter of days. Additionally, because the Total Shield can be easily removed, it can be reused if the TomoTherapy system is eventually moved to a new location.

“Total Shield is the most recent example of how the TomoTherapy system’s unique design, and its small footprint, can allow hospitals and cancer centers to easily adopt cutting-edge cancer care technology in places where other solutions are not feasible,” said Harry Freeman, director of commercial operations at TomoTherapy. “Combined with the TomoTherapy system’s integrated beam stop technology, Total Shield can dramatically reduce the cost of building out a vault with extensive shielding, and enables facilities to get their TomoTherapy system up and running much quicker than other radiation treatment solutions.”

Total Shield was designed collaboratively by NELCO and will be on display in the TomoTherapy booth (#6406) at RSNA 2010, November 28 – December 3, at McCormick Place in Chicago, Illinois.

About NELCO 
NELCO, an ISO 9001:2008 certified company, is an industry leader in the design, manufacturing, and installation of specialized products and services, for the medical, industrial, and construction fields. Such products include shielding for medical radiation therapy, medical diagnostic imaging, anti-corrosive linings, and industrial radiation shielding. With offices around the US, United Arab Emirates, the United Kingdom and China, NELCO always has a facility nearby, cutting shipping costs, and helping excel in customer service. For more information, visit http://www.nelcoworldwide.com, or call 1-781-933-1940.

About TomoTherapy Incorporated 
TomoTherapy Incorporated develops, markets and sells advanced radiation therapy solutions that can be used to treat a wide variety of cancers, from the most common to the most complex. The ring gantry-based TomoTherapy® platform combines integrated CT imaging with conformal radiation therapy to deliver sophisticated radiation treatments with speed and precision while reducing radiation exposure to surrounding healthy tissue. TomoTherapy’s suite of solutions includes its flagship Hi·Art® treatment system, which has been used to deliver more than three million CT-guided, helical intensity-modulated radiation therapy (IMRT) treatment fractions; the TomoHD™ treatment system, designed to enable cancer centers to treat a broader patient population with a single device; and the TomoMobile™ relocatable radiation therapy solution, designed to improve access and availability of state-of-the-art cancer care. TomoTherapy’s stock is traded on the NASDAQ Global Select Market under the symbol TOMO. To learn more about TomoTherapy, please visit TomoTherapy.com.

©2010 TomoTherapy Incorporated. All rights reserved. TomoTherapy, Tomo, TomoHD, TomoDirect, TQA, the TomoTherapy logo and Hi·Art are among trademarks, service marks or registered trademarks of TomoTherapy Incorporated in the United States and other countries.

Investor Contact:
Thomas E. Powell
Chief Financial Officer
608.824.2800
Email Contact

Media Contacts:
Kevin O’Malley
Manager, Corporate Communications
608.824.3384
Email Contact

Susan Lehman
Rockpoint Public Relations
510.832.6006
Email Contact

Filed Under: Public Health and Research

OtterBox Increases "Strength" of BlackBerry Torch 9800 Smartphone

Posted on November 23, 2010 Written by Editor

SOURCE: OtterBox

FORT COLLINS, CO–(Marketwire – November 23, 2010) – Available for various BlackBerry® smartphones, the pink OtterBox® “Strength” line now offers protection for the BlackBerry® Torch™ 9800 smartphone. These innovative Commuter Series® cases are a stylish way to keep the BlackBerry Torch smartphone pristine while supporting a good cause. OtterBox donates 10 percent of the purchase price from each “Strength” case to the Avon Breast Cancer Crusade to support research to find a cure for breast cancer and programs that provide access to breast health care, regardless of a person’s ability to pay.

“Supporting the Avon Breast Cancer Crusade has been an amazing opportunity for OtterBox and our customers,” said OtterBox founder and CEO Curt Richardson. “We’ve enjoyed the reveal of each new ‘Strength’ case and to date have donated more than $80,000 to the cause.”

The OtterBox Commuter Series case for the BlackBerry Torch smartphone is unlike any other case on the market, providing customized layers for extra protection. First, a white silicone skin fits snuggly around the back with plugs that fit precisely into all ports to prevent damage from dirt and dust. Second, a pink polycarbonate shell snap onto the front and another piece to the back allowing full functionality of the phone’s sliding feature and touch screen. The case also includes a self-adhering screen protector to keep the display scratch free.*

See the complete pink line for all you BlackBerry smartphones, available at www.otterbox.com/strength. 

Additional information for OtterBox Commuter Series for the BlackBerry Torch 9800 smartphone:

Environmental Protection:

  • Added protection against bump and shock

Colors:

  • Silicone: white
  • Polycarbonate: pink

Dimensions (case only):

  • 4.56″ (115.71 mm) x 2.64″ (67.11 mm) x 0.72″ (8.28 mm)

Approximate Weight (case only):

  • 0.80 oz (22.68 g) 

About the Avon Breast Cancer Crusade:

The Avon Foundation for Women’s Avon Breast Cancer Crusade has supported programs in more than 50 countries since its creation in 1992 and to date has raised and awarded more than $640 million worldwide for advancing access to care and finding a cure for breast cancer, with a focus on the medically underserved. Funding supports five areas: awareness and education; screening and diagnosis; access to treatment; support services; and scientific research. For more information or free printable breast cancer information, visit www.avonfoundation.org. For information about participating in the Avon Walk for Breast Cancer events, visit www.avonwalk.org.

About OtterBox:

Built upon fundamentals of hard work, innovation and perseverance, OtterBox is a leader in the production of premier protective solutions for global handheld manufacturers, wireless carriers and distributors.

Incorporating creativity and cutting-edge design into every product, OtterBox creates sleek and durable cases that offer reliable device protection to complement any lifestyle.

OtterBox was founded in 1998 and is headquartered in Fort Collins, Colo.

For more information, visit www.otterbox.com or call 888-695-8820. We’ve Got Technology Covered.

Notes:

*Commuter Series cases NOT protected against water. Will provide some added protection against bump and shock.

The BlackBerry and RIM families of related marks, images and symbols are the exclusive properties and trademarks of Research In Motion Limited.

©2010 Otter Products, LLC. All rights reserved. OtterBox and all OtterBox logos, trademarks and symbols are the property of Otter Products, LLC.

Contact:
Kristin Golliher
(970) 372-6232
[email protected]

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Filed Under: Public Health and Research

First Annual Grayson’s Gift Foundation Event Raises Over $150,000 for Pediatric Brain Cancer Research

Posted on November 23, 2010 Written by Editor

SOURCE: Grayson’s Gift Foundation

SANTA MONICA, CA–(Marketwire – November 22, 2010) – The first annual Grayson’s Gift Foundation Event, hosted on November 11, 2010, was a huge success, raising more than $150,000. The charity event took place in the ballroom at Hotel Casa del Mar in Santa Monica.

Grayson’s Gift Foundation is a non-profit committed to raising money for the brain cancer research department at the Children’s Hospital of Los Angeles. Money was raised through ticket sales, an extravagant silent auction, and generous donations made by attendees.

The Grayson’s Gift Foundation was founded in 2010 by Leslie and Cliff Katab, whose son Grayson died from a brain tumor just over two years ago. Cliff Ketab said, “We went through many surgeries and chemo and countless days in hospitals, as well as traveling to Europe for experimental treatments. Although we did everything humanly possible, we lost our beloved baby boy two years ago.

“Pediatric brain cancer is the second leading cause of children’s death only behind social causes (car accidents, etc). Being immersed in this world taught us many life lessons. One thing we know is that we must help find a cure for these children. We created Grayson’s Gift Foundation just for this reason. Our charity donates its contributions directly to support research and training for pediatric brain cancer.”

A festive evening, it was a fusion of determined oncologists, compassionate celebrities, friends and family. Thrown into the mix were individual demonstrations of state-of-the-art brain-computer controlled games using NeuroSky technology. The day before the event, NeuroSky donated several games to the pediatric cancer ward at Children’s Hospital Los Angeles. At the event, David Westendorf, Vice President of NeuroSky, talked about how Children’s Hospital LA saved his niece’s life, and then he gave away NeuroSky-powered Mindflex games from Mattel as table prizes.

Celebrity guests included: actor Jonathon Goldsmith, recognized as “The Most Interesting Man in the World” in recent Dos Equis commercials; Corey Feldmen of “The Goonies”; Taylor Armstrong of Bravo’s “Real Housewives of Beverly Hills”; Vienna Girardi who starred in ABC’s “The Bachelor”;” Jennifer Elise Cox, known for her appearance in The Brady Bunch Movie; actress Delphine Chaneac; and actor James Preston of “The Gates.”

Photos: http://www.ballantinesbiz.com/Green_Oct_2010/CHLA/CHLA_GraysonsGift_112210.html

Contact:
Kelley Coughlan
Email Contact
Ballantines PR
LA Office:
Tel: 310 454 3080
Cell: 310 570 9970

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Filed Under: Public Health and Research

Midwest Center for Emerging Infectious Diseases Combats Epidemic Outbreaks

Posted on November 22, 2010 Written by Editor

SOURCE: University of Cincinnati Foundation

The University of Cincinnati’s Collaborative Research Center Identifies Effective Treatments for Epidemic and Bio-Terrorism Attacks

CINCINNATI, OH–(Marketwire – November 22, 2010) – In the midst of flu season, millions of Americans are rushing to get vaccinated before becoming one of the approximately 200,000 flu victims the Centers for Disease Control (CDC) estimates are hospitalized every year. They aren’t the only ones suffering: according to study findings presented in a 2006 CNN story, the flu and other infectious disease outbreaks cost the nation’s employers about $10 billion a year.

That’s why the University of Cincinnati’s Midwest Center for Emerging Infectious Diseases (MI-CEID) exists. The center serves as a touchstone for advanced medical breakthroughs to provide protection and preparedness for biological events throughout the country — including bioterrorism, biological threats, pandemic outbreaks and even seasonal flu viruses.

“The best way to head off potential public health disasters is to have a targeted means to prevent, quickly diagnose, contain and treat infections. This can only be possible through diligent and comprehensive interdisciplinary research,” said Malak Kotb, Ph.D., chair of the department of molecular genetics, biochemistry and microbiology at the University of Cincinnati College of Medicine, and senior career research scientist at the VA Medical Center.

The MI-CEID is a unique model for collaboration across diversified medical disciplines, including:

  • UC Academic Health Center;
  • Local hospitals including the Cincinnati Children’s Hospital Medical Center;
  • Environmental Protection Agency (EPA);
  • VA Medical Center;
  • Regional health department;
  • Public safety agencies;
  • Community leaders;
  • Professional associations.

“Solutions to disease treatment and prevention require innovation — and you can’t be innovative and be in silos. We achieve the best outcomes by utilizing teams of people who are skilled in their areas of knowledge,” said Kotb. “By doing this, we create something novel and effective. We need to be ahead of the curve, and at UC we have the capabilities and technology to be able to make these strides in healthcare.”

Kotb credits the cross-disciplinary nature of UC’s research facility as key to the center’s early and continued successes. Whereas similar research centers rely on collaborators that may be spread across the country, the MI-CEID brings researchers from each of the organizations above, plus the university’s College of Medicine, under one roof for optimal communication and exchange of ideas and expertise.

To combat potential health threats, the collaborative team uses a state-of-the-art approach to identify and study different types of infectious bacteria, viruses and toxins to improve their detection. The team is also conducting research to identify genetic markers that may predict disease severity in individual patients and inform the most beneficial treatment for each based on genotypes of their DNA. 

“Once we find which genes are engaged in the disease process, we can determine how they are connected through the biological networks that influence disease,” said Kotb. “This allows us to create a roadmap that can predict responses, increase protection, reduce the severity or prevent the illness or disease altogether. This helps save time, money and lives when outbreaks occur.”

Organizations have been quick to realize the potential of the MI-CEID: the National Institutes of Health (NIH), the Department of Defense and Homeland Security, the Defense Threat Reduction Agency (DTRA) and other government agencies have tapped the center for research projects with national implications. In addition, Kotb cites the importance of private support via UC’s billion-dollar Proudly Cincinnati fundraising campaign. The center also relies on corporations that contribute to the research center’s ability to remain operational year-round and expand on its research capabilities.

But while this support can fund specific research initiatives, Kotb says that funding for truly cutting-edge research can sometimes be scarce. Financial support and partnerships are always being sought to further support research and discovery, build a stronger infrastructure, and attract high caliber scientists to effectively fight existing and emerging pathogens. These activities create jobs and boost the economy.

“Private industry is an essential ingredient to successful disease-mitigation and prevention strategies. Without private support to spur on ground-breaking research, essential studies –including those that can predict infection severity in different patients and/or can help suggest the best treatment strategies, and/or predict adverse reactions to certain drugs or vaccines can certainly save lives and reduce medical costs,” Kotb said.

There will always be another pandemic disease or public health scare, but with the UC’s MI-CEID program unique vision and collaborative model the treatments will be more timely and effective. For more information on this innovative program, visit www.uc.edu.

About the University of Cincinnati
 
Ranked by the National Science Foundation among the top 20 public, urban research universities in the United States, the University of Cincinnati is the region’s largest employer, with a diverse student population of more than 39,000. UC’s faculty has distinguished themselves worldwide for their creative teaching and research, including members of the National Academy of Science, Institute of Medicine and winners of Tony, Grammy and Pulitzer Prizes. The University’s 15 Colleges set the foundation for a university dedicated to undergraduate, graduate, and professional education, experience-based learning, and research. U.S. News has described UC as one of 15 “up and coming” universities and Forbes Magazine named UC one of the world’s most beautiful campuses.

About the University of Cincinnati Foundation
The University of Cincinnati Foundation is leading Proudly Cincinnati: Tower of Strength, Rock of Truth, the University’s most ambitious campaign in history, supporting the vision for UC to become the finest urban research university in the United States. Proudly Cincinnati’s goal is to raise $1 billion by 2013. To date, approximately $696 million has been raised for scholarships, innovative teaching and groundbreaking research. For more information about the Proudly Cincinnati campaign, visit www.uc.edu/foundation.

The University of Cincinnati Foundation
University Hall, Suite 100
51 Goodman Drive
Cincinnati, OH 45219
www.ProudlyCincinnati.org
www.Twitter.com/ProudlyCincy
www.Facebook.com/ProudlyCincinnati

Media Contact:
Lauren Boettcher
UC Foundation
(513) 556-7703 desk
(513) 460-5648 cell
Email Contact

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Filed Under: Public Health and Research

Advancing Diabetes Therapies, Integrium Clinical Research Finds the Sweet Spot

Posted on November 22, 2010 Written by Editor

SOURCE: Integrium

TUSTIN, CA–(Marketwire – November 22, 2010) – November is American Diabetes Month and Integrium LLC, a Contract Research Organization (CRO) with a therapeutic focus on cardiovascular and metabolic diseases, is at the forefront of clinical research to improve diabetes treatment. Eileen McAuley, Chief Operating Officer of Integrium, explains that the company has conducted 18 clinical trials of interventions for diabetes at 557 study sites. In addition to trials targeting diabetes, Integrium has conducted more than 100 cardiovascular and renal disease trials, which have an impact on diabetes care since diabetes is a leading cause of kidney failure and more than two-thirds of people with diabetes die of heart disease or stroke.

Integrium’s dedicated team of clinical researchers specializing in diabetes has pioneered therapies to improve the quality of life for people living with diabetes. Integrium’s Director of Project Management and Field Operations, Liza Moore, heads up a team with special expertise in wound healing. She explains that diabetic foot ulcers are among the most serious complications of the disease and untreated, often result in infection and amputation. “Our experience encompasses not only drugs to help manage blood glucose, but also medical devices such as bioengineered tissue products to speed wound healing. We are interested in preventing complications and effective treatment for those that can not be prevented.”

Integrium founder Dr. David H. G. Smith observes that the diabetes epidemic is not limited to the U.S. “One of our recent diabetes trials followed subjects in India, which has the largest diabetes population in the world, as well as subjects in the United States.” With its global reach, Integrium has completed trials in North America, Central and South America, the European Union and Asia for 12 of the top 20 biopharmaceutical companies.

About Diabetes
The United States is in the throes of a diabetes epidemic. An estimated 24 million children and adults have diabetes. Another 57 million others have pre-diabetes, elevated blood glucose levels that increase their risk of developing diabetes, heart disease and stroke.

One in ten American adults has diabetes and the Centers for Disease Control and Prevention (CDC) say that number could triple in the coming decades. The disease is the seventh leading cause of death in the U.S. and it is likely to be underreported as a cause of death.

Diabetes is a leading cause of kidney failure, blindness, amputations and pregnancy complications. Tighter blood glucose control reduces the symptoms and life-threatening complications of diabetes.

About Integrium, LLC
Integrium is a full-service clinical research organization (CRO) designing, conducting, and analyzing clinical trials for pharmaceutical research in dermatology, cardiovascular and metabolic disorders. It is committed to focused, specialized and long-term personalized service to its partners. It has a strong reputation for delivering high-quality management of clinical development programs. Combining the Integrium Clinical Excellence (ICE) study start-up and management methodology and therapeutic expertise leads sponsors to more confident, better-informed drug and device development decisions. For more information please visit www.integrium.com.

For More Information, Contact:
Juli Greenwood
CHEN PR, Inc.
781-672-3137
Email Contact

Filed Under: Public Health and Research

UPDATE: Phase 2b Study Demonstrates GlobeImmune’s GI-5005 HCV Therapeutic Vaccine Increases Sustained Virologic Response by 12 Percent in Patients Who…

Posted on October 30, 2010 Written by Editor

SOURCE: GlobeImmune Inc.

Additional Data Suggest That Cellular Immunity May Be a Fundamental Deficit in Hardest-to-Treat IL28B T/T Genotype Patients and Is Corrected by GI-5005

Data to Be Presented at Annual Meeting of the American Association for the Study of the Liver Diseases

LOUISVILLE, CO–(Marketwire – October 30, 2010) –  GlobeImmune Inc. today announced additional data from the GI-5005-02 Phase 2b study demonstrating that GI-5005, the Company’s investigational Tarmogen® product, improved sustained virologic response (SVR) by 12% in patients with genotype 1 chronic hepatitis C virus (HCV) infection who had failed prior treatment with standard of care (SOC, pegylated-interferon alpha 2a plus ribavirin). This study suggests that GI-5005 may have the potential to be the first successful therapeutic vaccine for patients chronically infected with HCV. 

Paul J. Pockros, M.D., of Scripps Clinic will deliver the oral presentation of the results in a late-breaker session at 6 p.m. EDT Monday November 1, 2010 at the 61st Annual Meeting of the American Association for the Study of the Liver Diseases (AASLD) in Boston.

On an intent-to-treat basis (subjects who received at least one dose of combination therapy), prior non-responders receiving GI-5005 plus SOC as a triple therapy had an SVR rate of 17%, compared to an SVR rate of only 5% in patients receiving SOC alone. Prior non-responders in this study were defined as patients who did not clear virus after a minimum of 12 weeks of SOC, including null responders, poor responders, and partial responders. Relapsers and on-treatment breakthroughs were not enrolled in the study. The most common adverse events associated with GI-5005 were injection site reactions that were generally mild and transient in nature. Discontinuation rates due to adverse events in the GI-5005 triple therapy arm were comparable to the discontinuation rates in the SOC alone arm.

“Only 4-7% of patients with genotype 1 HCV who were null, poor or partial responders to their first course of pegylated interferon-based therapy would be expected to achieve a sustained virologic response with a second course of treatment,” said Dr. Pockros. “In this study, GI-5005 conferred a three-fold improvement in SVR, an important treatment effect in this challenging patient population.” 

Additional immunology data from the study will be presented in a poster on Tuesday, November 2, 2010 by John M. Vierling, M.D., of Baylor College of Medicine. These data show that GI-5005 improved HCV-specific T cell responses 10-fold over SOC alone in patients with the IL28B T/T genotype (~20% of chronically infected patients), the subgroup most likely to fail treatment with SOC alone. Patients with the IL28B T/T genotype receiving SOC alone had an HCV-specific cellular immune response that was 17-fold lower than patients in the IL28B C/C or C/T subgroups. The improved HCV-specific T cell immunity in IL28B T/T patients receiving GI-5005 plus SOC correlates with previously reported data that demonstrated GI-5005 increased SVR rates by 60% in interferon-naïve T/T patients compared to T/T patients receiving SOC alone.

“These data suggest that the fundamental deficit in patients carrying the T allele of the IL28B gene is a deficit in adaptive cellular immunity, the mechanism that GI-5005 was designed to address,” said David Apelian, M.D., Ph.D., Chief Medical Officer at GlobeImmune. “We are confident that GI-5005 will become a cornerstone of HCV therapy, particularly for difficult to treat populations, such as IL28B T/T patients.”

A 40 patient expansion of this study in patients having the IL28B T/T genotype was initiated last week to further explore the potential treatment effect of GI-5005 in this patient population.

GI-5005 is a therapeutic vaccine candidate designed to generate HCV-specific T-cell responses and improve virologic responses in patients with chronic hepatitis C virus infection. 

About GlobeImmune

GlobeImmune Inc. is a private company developing therapeutic vaccines called Tarmogens for the treatment of cancer and infectious diseases. Tarmogens generate activated killer T cells that are designed to locate and eliminate virally-infected cells and/or cancer cells. The Company’s lead product candidate, GI-5005, is a Tarmogen being developed for the treatment of chronic hepatitis C virus (HCV) infection. GI-5005 is designed to complement both the current standard of care and emerging novel therapies for HCV. The Company’s lead oncology program, GI-4000, targets cancers caused by mutated versions of the Ras oncoprotein. GI-4000 is being investigated in clinical trials for the treatment of pancreas cancer as well as other cancers that contain mutated Ras, including non-small cell lung cancer and colorectal cancer. In May 2009, the Company announced a global partnership with Celgene focused on the discovery, development and commercialization of multiple product candidates for the treatment of cancer.

For additional information, please visit the company’s website at www.globeimmune.com.

This news release and the anticipated presentation contain forward-looking statements that involve risks and uncertainties, including statements relating to initiation and progress of the Company’s clinical trial programs and the results from the clinical trials. Actual results could differ materially from those projected and the Company cautions readers not to place undue reliance on the forward-looking statements contained in the release and anticipated presentation.

Filed Under: Hospitals and Health Systems, Public Health and Research

Phase 2b Study Demonstrates GlobeImmune’s GI-5005 HCV Therapeutic Vaccine Increases Sustained Virologic Response by 12 Percent in Patients Who…

Posted on October 30, 2010 Written by Editor

SOURCE: GlobeImmune Inc.

Additional Data Suggest That Cellular Immunity May Be a Fundamental Deficit in Hardest-to-Treat IL28B T/T Genotype Patients and Is Corrected by GI-5005

Data to Be Presented at Annual Meeting of the American Association for the Study of the Liver Disease

LOUISVILLE, CO–(Marketwire – October 30, 2010) –  GlobeImmune Inc. today announced additional data from the GI-5005-02 Phase 2b study demonstrating that GI-5005, the Company’s investigational Tarmogen® product, improved sustained virologic response (SVR) by 12% in patients with genotype 1 chronic hepatitis C virus (HCV) infection who had failed prior treatment with standard of care (SOC, pegylated-interferon alpha 2a plus ribavirin). This study suggests that GI-5005 may have the potential to be the first successful therapeutic vaccine for patients chronically infected with HCV. 

Paul J. Pockros, M.D., of Scripps Clinic will deliver the oral presentation of the results in a late-breaker session at 6 p.m. EDT today at the 61st Annual Meeting of the American Association for the Study of the Liver (AASLD) in Boston.

On an intent-to-treat basis (subjects who received at least one dose of combination therapy), prior non-responders receiving GI-5005 plus SOC as a triple therapy had an SVR rate of 17%, compared to an SVR rate of only 5% in patients receiving SOC alone. Prior non-responders in this study were defined as patients who did not clear virus after a minimum of 12 weeks of SOC, including null responders, poor responders, and partial responders. Relapsers and on-treatment breakthroughs were not enrolled in the study. The most common adverse events associated with GI-5005 were injection site reactions that were generally mild and transient in nature. Discontinuation rates due to adverse events in the GI-5005 triple therapy arm were comparable to the discontinuation rates in the SOC alone arm.

“Only 4-7% of patients with genotype 1 HCV who were null, poor or partial responders to their first course of pegylated interferon-based therapy would be expected to achieve a sustained virologic response with a second course of treatment,” said Dr. Pockros. “In this study, GI-5005 conferred a three-fold improvement in SVR, an important treatment effect in this challenging patient population.” 

Additional immunology data from the study will be presented in a poster on Tuesday, November 2, 2010 by John M. Vierling, M.D., of Baylor College of Medicine. These data show that GI-5005 improved HCV-specific T cell responses 10-fold over SOC alone in patients with the IL28B T/T genotype (~20% of chronically infected patients), the subgroup most likely to fail treatment with SOC alone. Patients with the IL28B T/T genotype receiving SOC alone had an HCV-specific cellular immune response that was 17-fold lower than patients in the IL28B C/C or C/T subgroups. The improved HCV-specific T cell immunity in IL28B T/T patients receiving GI-5005 plus SOC correlates with previously reported data that demonstrated GI-5005 increased SVR rates by 60% in interferon-naïve T/T patients compared to T/T patients receiving SOC alone.

“These data suggest that the fundamental deficit in patients carrying the T allele of the IL28B gene is a deficit in adaptive cellular immunity, the mechanism that GI-5005 was designed to address,” said David Apelian, M.D., Ph.D., Chief Medical Officer at GlobeImmune. “We are confident that GI-5005 will become a cornerstone of HCV therapy, particularly for difficult to treat populations, such as IL28B T/T patients.”

A 40 patient expansion of this study in patients having the IL28B T/T genotype was initiated last week to further explore the potential treatment effect of GI-5005 in this patient population.

GI-5005 is a therapeutic vaccine candidate designed to generate HCV-specific T-cell responses and improve virologic responses in patients with chronic hepatitis C virus infection. 

About GlobeImmune

GlobeImmune Inc. is a private company developing therapeutic vaccines called Tarmogens for the treatment of cancer and infectious diseases. Tarmogens generate activated killer T cells that are designed to locate and eliminate virally-infected cells and/or cancer cells. The Company’s lead product candidate, GI-5005, is a Tarmogen being developed for the treatment of chronic hepatitis C virus (HCV) infection. GI-5005 is designed to complement both the current standard of care and emerging novel therapies for HCV. The Company’s lead oncology program, GI-4000, targets cancers caused by mutated versions of the Ras oncoprotein. GI-4000 is being investigated in clinical trials for the treatment of pancreas cancer as well as other cancers that contain mutated Ras, including non-small cell lung cancer and colorectal cancer. In May 2009, the Company announced a global partnership with Celgene focused on the discovery, development and commercialization of multiple product candidates for the treatment of cancer.

For additional information, please visit the company’s website at www.globeimmune.com.

This news release and the anticipated presentation contain forward-looking statements that involve risks and uncertainties, including statements relating to initiation and progress of the Company’s clinical trial programs and the results from the clinical trials. Actual results could differ materially from those projected and the Company cautions readers not to place undue reliance on the forward-looking statements contained in the release and anticipated presentation.

Filed Under: Hospitals and Health Systems, Public Health and Research

Cosmetic Surgery Magazine: Reconstructive Surgeons Essential for Breast Cancer Patients

Posted on October 29, 2010 Written by Editor

SOURCE: New You Publishing

MIAMI BEACH, FL–(Marketwire – October 29, 2010) –  When it comes to breast cancer, removal of the cancerous tissue is only part of the healing process. Reconstructing the breast at the same time can be critical for the wellbeing — and even survival — of the patient.

In support of Breast Cancer Awareness Month, New You magazine’s current issue addresses the issue of breast reconstruction at the time of initial surgery. In fact, say experts interviewed by New You, having a cosmetic or plastic surgeon involved right from the start means a more successful outcome for recreating a normal appearance and returning a woman’s sense of self and self-confidence.

“The cosmetic surgeon should be consulted right away, prior to any other surgery, and it should be a joint effort between the plastic or cosmetic surgeon and the breast surgeon,” says Dr. Michael S. Kluska, a board-certified plastic and cosmetic surgeon who practices near Pittsburgh, PA.

According to New You, the national consumer magazine for cosmetic surgery, the reasons for this include making sure the procedure performed by the breast surgeon removing the cancer is done so that optimal reconstruction is possible. The results can make a huge difference for the patient.

“Patients who undergo a mastectomy with simultaneous reconstruction tend to have better results long term than those who have the mastectomy [and] wait a few years,” Dr. Kluska told the magazine.

Kluska’s comments are supported by new research released last week in Toronto at the joint annual scientific meetings of the American Society of Plastic Surgery and the Canadian Society of Aesthetic Plastic Surgery, which showed that reconstruction of the breast immediately after mastectomy is associated with significantly improved breast-cancer-specific survival. Analysis of figures from the U.S. National Cancer Institute showed a 26% reduction in breast-cancer specific mortality for patients with immediate reconstruction; reasons included reduced depression and an improved sense of wellbeing.

About New You Magazine

New You is the official magazine of the American Academy of Cosmetic Surgery (AACS), published by Miami Beach-based New You Publishing, LLC. The mission of New You is to inform readers about the latest cosmetic procedures, to educate them about safety, cost and personal experience, and to locate the best possible cosmetic surgeon. For more information visit: http://newyoumag.com.

About The American Academy of Cosmetic Surgery

The American Academy of Cosmetic Surgery is a professional medical society dedicated to patient safety and physician education in cosmetic surgery. The AACS represents cosmetic surgeons in the American Medical Association through its seat in the AMA House of Delegates. Members of AACS are dermatological, facial plastic, head and neck, oral and maxillofacial, general, plastic, gynecological or ocular plastic surgeons specializing in cosmetic surgery. Founded in 1985, the AACS has over 2,500 members.

For further information please contact:
J.P. Faber
New You editor-in-chief
Email Contact
305-590-8549

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Filed Under: Hospitals and Health Systems, Public Health and Research

New Study: Saints Mary and Elizabeth Medical Center Ranks in Top 5 Percent for Stroke, Gastrointestinal Surgery/Care

Posted on October 27, 2010 Written by Editor

SOURCE: Resurrection Health Care

CHICAGO, IL–(Marketwire – October 27, 2010) –  Saints Mary and Elizabeth Medical Center (SMEMC) is among the top 5 percent of U.S. hospitals for stroke care, gastrointestinal surgery and gastrointestinal care, according to a newly published health care study.

SMEMC ranks fifth in the state for gastrointestinal surgery and gastrointestinal care.

The nation’s nearly 5,000 hospitals were included in this sweeping study, which examined mortality rates and complication rates. The 13th Annual HealthGrades Hospital Quality in America study, the largest annual report of its kind, analyzed patient outcomes from nearly 40 million Medicare hospitalization records from 2007 to 2009. HealthGrades, an independent ratings company, conducted the study.

For 2011, SMEMC was recognized with nine clinical achievements:

  • HealthGrades Stroke Care Excellence Award™ (second year in a row)
  • HealthGrades Gastrointestinal Surgery Excellence Award™
  • HealthGrades Gastrointestinal Care Excellence Award™
  • Five-star ratings, the highest level, in six areas — heart attack, pneumonia, sepsis (complication of a serious bacterial infection), gastrointestinal bleed, bowel obstruction and cholecystectomy (gall bladder removal)

“Our mission — since we opened our doors 123 years ago — is to provide patients with the highest level of quality care,” said Margaret McDermott, executive vice president/chief executive officer, SMEMC. “I am proud of our entire health care team for their commitment to delivering excellent care with excellent results.”

McDermott said patients are increasingly seeking independent information on hospital quality performance. “I hope this study will help guide individuals confronted with important health care decisions,” she said.

According to the study, top-performing hospitals had dramatically lower mortality rates than other hospitals. HealthGrades analyzed mortality rates for 17 procedures and diagnoses. Results showed that patients at hospitals ranking in the top 5 percent had a 72 percent lower chance of dying when compared with the lowest-performing hospitals, and a 53 percent lower chance of dying when compared to the U.S. national average.

HealthGrades rates hospitals independently based on data that hospitals submit to the Centers for Medicare and Medicaid services, part of the U.S. Department of Health and Human Services.

To read the full study and FAQ, visit http://www.reshealth.org/sub_smemc/about/healthgrades/default.cfm.

About SMEMC
Part of Resurrection Health Care, SMEMC is an award-winning medical center on Chicago’s near northwest side and includes two campuses: Saint Mary Campus, 2233 W. Division St., and Saint Elizabeth Campus, 1431 North Claremont Ave. Visit smemc.reshealthcare.org.

Contact:
Russell Milligan
Saints Mary and Elizabeth Medical Center
312-770-2225
Email Contact

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Filed Under: Hospitals and Health Systems, Public Health and Research

Future of European Flu Vaccine Market Rife With Innovation

Posted on October 26, 2010 Written by Editor

SOURCE: Kalorama Information

NEW YORK, NY–(Marketwire – October 26, 2010) –  In 2009, the adult in flu vaccine market in Europe reached new heights with nearly $1.6 billion in revenues, up a whopping 81.4% from the prior year. According to healthcare market research publisher Kalorama Information’s newly published “European Vaccine Markets,” this surge in flu vaccine sales was due to products developed to address the H1N1 flu pandemic.

Influenza vaccines are responsible for almost half of the adult vaccine market in 2010. Although Kalorama does not foresee the same kind of growth witnessed in 2009, the publisher expects strong demand for flu vaccines to continue, tempered by a near term decrease in demand for pandemic vaccines. Flu vaccine revenues should reach $2.6 billion by 2014, supported by an aging population and expanded recommendations for adult influenza vaccinations.

“The swine flu pandemic of 2009 prompted a flurry of activity in the flu vaccines market around the world, with a resulting surge in revenues,” says Bruce Carlson, publisher of Kalorama Information. “This growth is unlikely to continue as governments overestimated the demand for H1N1 flu vaccines and found themselves with excess stock. Current development initiatives focus on products that protect against pandemic outbreaks, specific strains of influenza and alternative administration routes.”

In May 2008, GlaxoSmithKline received European approval for Prepandrix and Pandemrix; each contains the H5N1 (avian flu) inactivated split, monovalent virus. Prepandrix is designed to be given before or at the onset of a declared influenza pandemic to prevent influenza caused by H5N1. It is formulated with a novel proprietary adjuvant system, which is designed to achieve a high immune response at a low dose of antigen, and to be long-lasting and active against a broad range of H5N1 strains. Pandemrix is approved for use when an H5N1 influenza pandemic has been officially declared by the WHO or European Union.

In December 2008, the European Medicines Agency (EMEA) issued a positive opinion for Baxter’s CELVAPAN, the first cell culture-based H5N1 pandemic vaccine, in the European Union. CELVAPAN is made using Baxter’s proprietary Vero cell technology, which speeds up the manufacturing process due to its ability to use the native virus which does not need to be modified in order to grow in chicken eggs. The shorter production time is critical in accelerating vaccine supply in response to an influenza pandemic.

Also of note are advancing efforts to develop a universal flu vaccine which would protect against multiple influenza strains, thereby significantly increasing effectiveness. While many companies over the years have investigated methods to achieve this, U.K.-based Immune Targeting Systems, with funding from a broad range of investors including Novartis’s venture capital group, is expected to begin studies of a product candidate in 2010.

More information on flu and other types of vaccines in the European market can be found in Kalorama Information’s “European Vaccine Markets.” This report presents market estimates and forecasts, product reviews and pipelines, issues and trends, and company profiles for pediatric and adult vaccines. The report can be found at: http://www.kaloramainformation.com/redirect.asp?progid=79864&productid=2833006.

About Kalorama Information
Kalorama Information supplies the latest in independent market research in the life sciences, as well as a full range of custom research services. We routinely assist the media with healthcare topics. Follow us on Twitter (http://www.twitter.com/KaloramaInfo) and LinkedIn (http://www.linkedin.com/groups?gid=2177845&trk=hb_side_g).

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Filed Under: Prescription Drugs and Pharmacy, Public Health and Research

Laura’s Journeys, an Organization Supporting Travel Therapy, Awards 3 Vacations to Cancer Patients at St. Luke’s-Roosevelt Hospital

Posted on October 26, 2010 Written by Editor

SOURCE: Laura’s Journeys

Grand Prize Winner Chosen by Lance Armstrong During Surprise Visit to Infusion Suite

NEW YORK, NY–(Marketwire – October 26, 2010) –  Patients undergoing treatment for cancer at St. Luke’s-Roosevelt Hospital were recently treated to a vacation giveaway and a surprise visit by seven-time Tour de France winner Lance Armstrong.

The renowned cancer survivor and founder of LIVESTRONG was joined by LIVESTRONG President and CEO Doug Ulman and American Cancer Society CEO Dr. John Seffrin on a tour of the hospital’s chemotherapy infusion suite. In addition to personally interacting with the patients, the prominent visitors gained first-hand knowledge of the hospital’s quality-of-life initiatives for cancer patients. These include art, music, and massage therapy programs funded by the Helen Sawaya Fund, as well as the travel therapy program funded by Laura’s Journeys (www.laurasjourneys.org).

During the Sept. 22nd visit, three vacations were awarded in the latest raffle from Laura’s Journeys, a support program for cancer patients at St. Luke’s-Roosevelt and other institutions within the Continuum Health Partners network, designed to encourage and facilitate recreational travel for patients along with their family members or friends. The three winners and a runner-up were drawn by Messrs. Armstrong, Ulman, Seffrin and previous Laura’s Journeys winner Rodney Carroll from over 80 entrants, all currently undergoing chemotherapy or radiation treatments. Prior to the drawing, Mr. Carroll told patients and others in the infusion suite about the life-changing impact of his family’s week-long visit to Greece in late-spring.

The latest drawing’s grand prize went to Aida George, 41, a resident of Yonkers, N.Y. being treated for breast cancer. Ms. George won accommodations for seven nights in a fully-furnished, five-bedroom, three-bath vacation home, complete with a private swimming pool and hot tub. The accommodations were donated by Pytha Realty Group of Merritt Island, http://www.pytharealty.com. The winner will travel to Merritt Island with her husband, three children, and her mother, later this fall. In addition to relaxing at the house and beach, the family plans to travel to nearby Orlando, where they will go to Disney World and other theme parks, and visit with family members who live in that area. Laura’s Journeys is providing funding for the family’s travel expenses.

The second winner, who requested privacy, is a 58-year-old male from Westchester County undergoing treatment for colorectal cancer. He will travel with his wife this fall to the Berkshire Mountains for a two-night stay at The Summer White House, a bed & breakfast in Lenox, Mass. 

The third winner, Jean Scheller, a 44-year old resident of Weehawken, N.J. being treated for ovarian cancer, also won a two-night stay at the Summer White House, where she will travel with a friend this fall. In addition to the accommodations, Laura’s Journeys is providing both Berkshires trip winners with funds for meals and local attractions. 

Laura’s Journeys was created by Aberdeen, N.J. resident Bill Parness in memory of his wife Laura, who passed away in November 2008 at the age of 54 after a courageous battle with breast cancer. He developed the program based on the therapeutic benefits he and Laura derived from their extensive travels during the six years she was being treated for advanced breast cancer. Since its inception in late 2009, Laura’s Journeys has sent St. Luke’s-Roosevelt Hospital patients on week-long cruises to the Caribbean and New England/Canada; week-long stays in Greece and Florida; and weekend getaways to the Berkshires. With these three latest trips, the program will have awarded nine vacations to patients in the space of a year. 

Laura Parness was a patient of Gabriel A. Sara, M.D., Medical Director of the Chemotherapy Infusion Suite and Executive Director of the Patient Services Initiative at Continuum Cancer Centers of New York, located at Roosevelt Hospital. As he was with Laura, Dr. Sara is a strong advocate for therapeutic travel for his patients.

“The benefits of our philanthropy programs — including Laura’s Journeys and the music, art and massage therapy programs funded by the Helen Sawaya Fund — are so immense that today, I can hardly imagine running the chemotherapy infusion suite without them,” said Dr. Sara. “Patients’ journeys are transformed as they feel they can play, dream and feel alive, all over again. The fact that LIVESTRONG and ACS chose to visit our unit because of our philanthropy program validates and reaffirms the power of our work. I hope it will help drum up financial support so we can continue to offer this life-altering support to our patients.”

He added: “Lance Armstrong’s visit was a very emotional experience for all of us. During his visit, he interacted with all of us and heard the testimonies of Fuad Sawaya and Bill Parness about their late wives, Helen and Laura, respectively. Lance was very engaged and curious to know more about these programs and how they have transformed the experience of patients and staff alike. During Lance’s interactions with every patient in our infusion suite, you could just feel that this was familiar territory and that he had been there, done that and survived a similar experience. It was touching to see him look into the patients’ eyes and inquire about their feelings. The patients, of course, were so moved. But the highlight of the visit was undeniably the Laura’s Journeys travel raffle. We always start by creating a certain atmosphere of festivity and playfulness. We gave out percussion instruments, and our music therapist played a Beatles song in the middle of the chemo suite, as guests, staff, patients and everyone began to sing. No one could believe this was a chemo suite in which 18 patients were receiving treatment.” 

In early 2010, LIVESTRONG announced they would recognize The Creative Center, a Manhattan-based group that runs the art therapy program at St. Luke’s-Roosevelt and 19 other New York area hospitals, as a “Model Program” and would work with them to expand their Artist in Residence program to 20 new cities across the U.S. This commitment makes LIVESTRONG the largest funder of the program and was the driving force behind Mr. Armstrong’s visit.

“The Creative Center provides patients with a connection to the things they like to spend time doing,” said Mr. Armstrong. “Being exposed to art and music has created a community among the patients that is inspirational. It has been amazing to see the result of LIVESTRONG‘s funding affecting patients in such an overwhelmingly positive way.”

Filed Under: Hospitals and Health Systems, Public Health and Research

Vicor Technologies Receives Institutional Review Board Approval for Study to Assess Concussion in NCAA Athletes Using Its PD2i Analyzer(TM)

Posted on October 26, 2010 Written by Editor

SOURCE: Vicor Technologies, Inc.

BOCA RATON, FL–(Marketwire – October 26, 2010) – David H. Fater, CEO of Vicor Technologies, Inc. (OTCBB: VCRT), today announced that the Company has received approval from the Institutional Review Board (IRB) at the University of Mississippi Medical Center for a study to assess concussions in competitive athletes using its PD2i Analyzer™. The study will be conducted in collaboration with the University of Mississippi Medical Center (UMMC) and Belhaven University. Vicor Technologies is a biotechnology company focused on the development of innovative, non-invasive medical devices using its patented, proprietary PD2i® nonlinear algorithm and software. Vicor is currently in the process of commercializing diagnostics that accurately risk stratify specific target populations for future pathological events, including congestive heart failure patients for cardiac death resulting from arrhythmia or pump failure, diabetics for diabetic autonomic neuropathy (DAN), and trauma victims for imminent death absent immediate lifesaving intervention.

“We’re pleased to have approval from UMMC’s IRB permitting us to commence this important study of concussion status in competitive athletes — a first for the PD2i Analyzer™. Being able to effectively assess the extent of a concussion and risk of follow-on pathological events in athletes will enable all involved in assessing the extent of harm incurred during competitive play to better determine player need for advanced care and/or player ability to continue to play unharmed. With this approval, we will begin enrolling patients for this important and exciting clinical research study with an NCAA school, which could lead to other similar studies in the future,” stated Mr. Fater.

The IRB reviews research to ensure that the federal regulations for protecting human research participants outlined in UMMC policy, the Department of Health and Human Services (DHHS) regulations (45 CFR 46) and the Food and Drug Administration (FDA) regulations (21 CFR Parts 50 & 56), as well as other requirements, are met. 

About Vicor Technologies, Inc.
Vicor Technologies is a biotechnology company creating innovative non-invasive diagnostics employing its patented, proprietary point correlation dimension algorithm (PD2i®). The PD2i® nonlinear algorithm is a deterministic, nonlinear measure of electrophysiological potentials that predicts future pathological events with a high degree of accuracy in target populations.

Vicor currently has three products employing the PD2i® nonlinear algorithm. The PD2i Analyzer™, which has FDA 510(k) marketing clearance, measures heart rate variability; physicians performing diagnostic tests with the PD2i Analyzer™ are able to receive reimbursement under existing CPT codes. The PD2i VS™ (Vital Sign), in clinical trials under a collaborative effort with the U.S. Army Institute for Surgical Research, risk stratifies combat and civilian trauma victims. The PD2i CA™ (Cardiac Analyzer), in multiple clinical trials, identifies patients at risk of cardiac death.

Vicor anticipates additional applications employing the PD2i® nonlinear algorithm to enable early detection and risk stratification for a variety of other disorders and diseases. Additional information is available at www.vicortech.com.

Disclaimer
The appearance of name-brand institutions, such as the University of Mississippi Medical Center Institutional Review Board, NCAA, and the U.S. Army Institute for Surgical Research, in this media release does not constitute endorsement by institutions of the information, products or services contained therein.

Caution Regarding Forward-Looking Statements
Forward-looking statements in this press release are based on current plans and expectations that are subject to uncertainties and risks, which could cause our future results to differ materially. The following factors, among others, could cause our actual results to differ: our ability to successfully complete the normal range study for PD2i®values; our ability to generate revenues from the sale of the PD2i Analyzer™; our ability to obtain FDA approval of our 510(k) submission to secure a claim for the PD2i CA™(Cardiac Analyzer) for assessing patients undergoing tests for cardiovascular disease and our ability to obtain marketing clearance from the FDA for the PD2i VS™ (Vital Sign) for military and civilian applications; our ability to develop additional applications for the PD2i®algorithm; our ability to continue to receive financing sufficient to continue operations and complete critical clinical trials; our ability to continue as a going concern; our ability to successfully develop products based on our technologies; our ability to obtain and maintain adequate levels of third-party reimbursement for our products; the impact of competitive products and pricing; our ability to receive regulatory approval for our products; the ability of third-party contract research organizations to perform preclinical testing and clinical trials for our technologies; the ability of third-party manufacturers to manufacture our products; our ability to retain the services of our key personnel; our ability to market and sell our products successfully; our ability to protect our intellectual property; product liability; changes in federal income tax laws and regulations; general market conditions in the medical device and pharmaceutical industries; and other matters that are described in Vicor’s Annual Report on Form 10-K for the fiscal year ended December 31, 2009 and subsequent filings with the Securities and Exchange Commission. Forward-looking statements in this press release speak only as of the date of the press release, and we assume no obligation to update forward-looking statements or the reasons why actual results could differ.

Release 10-21

CORPORATE CONTACT
David H. Fater
Vicor Technologies, Inc.
561.995.7313
[email protected]

INVESTOR CONTACT
Richard Moyer
Cameron Associates
212.554.5466
[email protected]

MEDIA CONTACT
Robin Schoen
Robin Schoen Public Relations
215.504.2122
[email protected]

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Filed Under: Public Health and Research

Crystal Research Associates LLC Issues Executive Informational Overview(R) (EIO(R)) on Radient Pharmaceuticals

Posted on October 25, 2010 Written by Editor

SOURCE: Radient Pharmaceuticals Corporation

NEW YORK, NY–(Marketwire – October 25, 2010) –  Crystal Research Associates, LLC announced today it has issued an Executive Informational Overview® (EIO®) on Radient Pharmaceuticals Corporation (RPC) (NYSE Amex: RPC). The full 64-page report can be found at www.crystalra.com.

Radient Pharmaceuticals Corporation (“Radient” or “the Company”) together with its wholly-owned subsidiary AMDL Diagnostics Inc. (ADI), is an in vitro (IVD) company commercializing Onko-Sure® (formerly DR-70®) — a non-invasive, IVD test kit that detects and monitors up to 19 types of cancer. Onko-Sure® helps physicians answer important clinical questions related to early disease detection and progression in order ultimately to improve patient outcomes and survival. The distinctive feature of Radient’s Onko-Sure® blood test is that it measures the accumulation of specific breakdown products in serum (blood) called fibrin and fibrinogen degradation products (FDPs). Research has found that FDP levels rise dramatically as cancer progresses. A potentially life-saving IVD cancer test, Onko-Sure® is currently cleared to monitor colorectal cancer (CRC) treatment/recurrence in the U.S.; to detect and monitor lung cancer in Canada; for use as a general cancer marker in Australia, Europe, India, Taiwan, and Vietnam; and for use in CRC patients in South Korea. Radient is working to obtain additional regulatory clearances for indications in the U.S. and abroad. Radient’s subsidiary, ADI, operates research and development and quality control laboratories and an ISO 13485:2003-certified manufacturing facility for Onko-Sure® production.

For additional information on Radient Pharmaceuticals, ADI and its portfolio of products visit the Company’s corporate website at www.Radient-Pharma.com. For Investor Relations information contact Kristine Szarkowitz at [email protected] or 1.206.310.5323.

About Radient Pharmaceuticals:
Headquartered in Tustin, California, Radient Pharmaceuticals is dedicated to saving lives and money for patients and global healthcare systems through the deployment of its Onko-Sure® In Vitro Diagnostic cancer test. The company’s focus is on the discovery, development and commercialization of unique high-value diagnostic tests that help physicians answer important clinical questions related to early disease detection; treatment strategy; and the monitoring of disease progression, prognosis, and diagnosis to ultimately improve patient outcomes. Radient Pharmaceutical’s current Onko-Sure® cancer test is used to guide decisions regarding patient treatment, which may include decisions to refer patients to specialists, perform additional testing, or assist in the selection of therapy. To learn more about our company, people and potentially life-saving cancer test, visit www.radient-pharma.com.

About Crystal Research Associates, LLC:
Crystal Research Associates, LLC is an independent research firm that provides institutional-quality, fee-based research to small- and mid-cap companies. Crystal Research Associates’ unique and novel product, the Executive Informational Overview® (EIO®), is free of investment ratings, target prices, and forward-looking financial models. The EIO® presents a crystal clear, detailed report on a company (public or private) in a manner that is easily understood by the Wall Street financial community. The EIO® details a company’s product/technology/service offerings, market size(s), key intellectual property, leadership, growth strategy, competition, risks, financial statements, key events, and other such fundamental information. Crystal Research Associates has offices in New York City, West Palm Beach, Montréal, and Toronto. Crystal Research Associates has been compensated by the Company in cash of sixty-one thousand U.S. dollars and four hundred thousand, four-year warrants for its services in creating this report, for updates, and for printing costs.

Forward Looking Statements:
Safe Harbor Statement under the Private Securities Litigation Reform Act of 1995: The statements contained in this document include certain predictions and projections that may be considered forward-looking statements under securities law. These statements involve a number of important risks and uncertainties that could cause actual results to differ materially including, but not limited to, the performance of joint venture partners, as well as other economic, competitive and technological factors involving the Company’s operations, markets, services, products, and prices. With respect to Radient Pharmaceuticals Corporation, except for the historical information contained herein, the matters discussed in this document are forward-looking statements involving risks and uncertainties that could cause actual results to differ materially from those in such forward-looking statements.

Radient Pharma Contact:
Kristine Szarkowitz
Director-Investor Relations
Email Contact
(Tel : ) 206.310.5323

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Filed Under: Prescription Drugs and Pharmacy, Public Health and Research

New Diabetes Device Next Step in the Quest for Closed-Loop System

Posted on October 21, 2010 Written by Editor

EDMONTON, ALBERTA–(Marketwire – Oct. 21, 2010) – Medtronic, Inc. (NYSE:MDT) announced today the Canadian launch of a novel technology designed to provide additional protection against the risks associated with hypoglycemia. This new device, currently available in more than 50 countries outside of the United States and now in Canada, can automatically suspend insulin delivery when the device senses that glucose levels have fallen to or below a pre-selected threshold. This feature is intended to reduce the severity of low blood sugar (hypoglycemia) in situations where patients ignore or are unable to treat hypoglycemia. Hypoglycemia, a dangerous and often frequent occurrence with diabetes, can be one of the most frightening aspects of living with type 1 diabetes. If left untreated, hypoglycemia can cause loss of consciousness, seizure, coma, or even death.1

Research indicates that, on average, a person with diabetes will experience more than one low blood sugar event every two weeks. Additionally, each year, nearly one in 14 people with insulin-treated diabetes will experience one or more episodes of severe hypoglycemia, requiring urgent treatment by a healthcare professional.2 A third of diabetes patients suffer from hypoglycemia while asleep, which may impair their ability to recognize or act to prevent a serious episode.3 An estimated 33 percent of diabetes-related deaths are a result of acute complications such as hypoglycemia.4 While most patients experience “warning signs” before a hypoglycemic event (such as feeling shaky, sweating, tingling in the lips, confusion and irritability), many others may not experience any warning signs at all.

“The Paradigm Veo, with its automatic feedback mechanism, is a major step forward in our commitment to improving glucose control in diabetics,” says Katie Szyman, president of the Diabetes business and senior vice president at Medtronic. “While not a cure for diabetes, we believe this automatic feature offers added protection, greater confidence and may lower the risk of injury associated with hypoglycemic events. Equally important, it will give patients and family members more peace of mind.”

The Paradigm Veo System includes an insulin pump with a continuous glucose monitoring (CGM) system (provided by means of a separate sensor and transmitter). The patient uses readings from the monitor to understand their current glucose level changes. Based on confirmatory fingerstick blood glucose measurements, the patient then programs the insulin pump to deliver an appropriate amount of insulin. Insulin combats high blood sugar, a key cause of heart disease and other long-term complications in type 1 diabetes.1 However, if data transmitted from the sensor show the patient’s glucose levels have dropped below a defined threshold, the device alarms to alert the patient. If these alarms are ignored, the insulin pump automatically suspends insulin delivery for up to two hours. This helps to protect against potentially dangerous hypoglycemic events. 

“This latest technology is a significant advance that will help people with diabetes to more safely optimize glucose control. In order to reduce the long-term risk of diabetes-related complications, which can cause blindness, kidney failure and heart attacks, patients should manage their glucose levels to as near normal as possible. Unfortunately, aggressive glucose control can increase the risk of severe hypoglycemia, which can render a patient unconscious—and if recurrent—can have very serious consequences,” says Dr. Bernard Zinman, Director of the Leadership Sinai Centre for Diabetes at Mount Sinai Hospital in Toronto. “For the first time, an insulin pump can now not only warn the patient of this dangerous situation but can also respond and thus help correct this undesirable situation. The Paradigm Veo alerts patients if their glucose levels drop too low, and stops the delivery of more insulin if they don’t respond to the alert. Having this safety feature may allow patients greater control over severe hypoglycemia.”

About the Diabetes Business at Medtronic

The Diabetes business at Medtronic (www.medtronicdiabetes.ca) is the world leader in advanced diabetes solutions, including integrated diabetes management systems, insulin pump technology, continuous glucose monitoring systems and management software, as well as world-class, 24/7 expert consumer and professional service and support.

About Medtronic

Medtronic, Inc., headquartered in Minneapolis, is the global leader in medical technology – alleviating pain, restoring health and extending life for millions of people around the world. More information is available at: www.medtronic.com.

Any forward-looking statements are subject to risks and uncertainties such as those described in Medtronic’s periodic reports on file with the Securities and Exchange Commission. Actual results may differ materially from anticipated results.

About Medtronic of Canada Ltd.

Medtronic of Canada sells, services and distributes Medtronic products in Canada: medical devices used in cardiovascular medicine, diabetes, spinal and neurosurgery, and ear, nose and throat surgery. Medtronic of Canada employs over 420 Canadians, it is headquartered in Brampton, Ontario, has an Operations Centre in Mississauga and regional offices in Vancouver and Montreal and an atrial fibrillation (AF) ablation catheter manufacturing facility – Medtronic CryoCath – in the Montreal metropolitan area.

References

1. Diabetes UK: http://www.diabetes.org.uk/Guide-to-diabetes/Complications/Hypoglycaemia/ (Accessed 23rd April 2009)

2. Leese GP, Wang J et al. Frequency of severe hypoglycemia requiring emergency treatment in type 1 and type 2 diabetes. Diabetes Care 26:1176-1180, 2003.

3. Pramming S, Thorsteinsson B et al. Nocturnal hypoglycemia in patients receiving conventional treatment with insulin. British Medical Journal 291(1985):376-379

4. Orchard TJ. International evaluation of cause-specific mortality and IDDM. Diabetes Care 14:55-60, 1991

Filed Under: Public Health and Research

Helix BioPharma Corp. Reports Positive Efficacy and Safety Findings From Phase II Study of Its Topical Interferon Alpha-2b in Patients With Low-Grade…

Posted on October 21, 2010 Written by Editor

SOURCE: Helix BioPharma Corp.

After Treatment, 71.4% of the Women No Longer Had Potentially Pre-Cancerous Low-Grade CIN 1 or CIN 2 Cervical Lesions

AURORA, ON–(Marketwire – October 21, 2010) –  Helix BioPharma Corp. (TSX: HBP) (NYSE Amex: HBP) (FRANKFURT: HBP), a biopharmaceutical company developing drug candidates for the prevention and treatment of cancer, today announced positive efficacy and safety findings from its recently completed Phase II pharmacokinetic study of Topical Interferon Alpha-2b in patients with low-grade cervical lesions. These findings build upon the positive pharmacokinetic findings from this study announced in the Company’s press release of June 23, 2010.

Using colposcopic directed biopsy to determine the treatment’s effectiveness, 71.4% of the women in the study no longer had potentially pre-cancerous, low-grade lesions known as cervical intraepithelial neoplasia grade 1 or 2 (CIN 1 or CIN 2) following treatment. Colposcopic directed biopsy is generally considered the leading method for diagnosing potential cervical precancer today. In addition, Topical Interferon Alpha-2b demonstrated an excellent safety profile, with no significant local intolerance findings and no serious adverse events.

There are approximately 1.3 million women diagnosed with CIN 1 or CIN 2 lesions each year in the U.S. alone. Currently, there are no pharmaceutical (non-surgical) treatments for these women. Available invasive/surgical techniques to treat CIN 1 or CIN 2 lesions are sometimes associated with serious unwanted side effects for patients, including cervical complications with pregnancy and conception. Accordingly, available invasive/surgical techniques are generally utilized only in the case of many months of long-term persistence and/or progression of CIN 1 or CIN 2 lesions, leaving patients uncertain and anxious about their prognosis in the interim.

“We are pleased with these findings because they provide further evidence of the potential effectiveness of Topical Interferon Alpha-2b for treating women with potentially precancerous, low-grade cervical lesions,” said John Docherty, president of Helix BioPharma Corp. “These findings suggest that Topical Interferon Alpha-2b could offer women a safe and immediate therapeutic alternative to today’s protracted observational and potentially problematic surgical approach to managing this disease. We are now awaiting approval by the U.S. Food and Drug Administration of our application to conduct an expanded U.S. Phase II/III randomized, double-blind, controlled, pivotal efficacy trial in patients with low-grade cervical lesions.”

The study also examined Papanicolaou (“Pap”) smear response rate as a secondary efficacy parameter in the patients. The finding was less pronounced with 35.7% of the women demonstrating resolution of their abnormal Pap smears. However, this study was specifically designed with a relatively short post-treatment follow-up period as it was principally intended to provide pharmacokinetic results. The Company was, therefore, not surprised by this finding. By comparison, the Company has previously reported a more pronounced Pap response rate in patients treated with Topical Interferon Alpha-2b when it employed a longer post-treatment follow-up period.

About the Clinical Study

The clinical study employed an open-label, single-arm design and enrolled a total of 14 female patients with low-grade cervical lesions. Eligible women were between 18 and 45 years of age, presented with mild to moderate CIN (CIN1 or CIN2 respectively) confirmed by biopsy/histology, had a cytological diagnosis of Pap IIID not older than 12 months and were human papillomavirus (HPV)-positive confirmed by the Hybrid Capture® 2 HPV-DNA test. The primary objective of the study was to determine the multiple-dose pharmacokinetic profile of Topical Interferon Alpha-2b following intravaginal application every other day of a total of 14 doses of the cream. Helix previously announced on June 23, 2010 that all 14 patients were found to have circulating interferon alpha-2b levels below the bioassay lower limit of detection (6.25 pg/mL) at all sampling time points. Following the pharmacokinetic portion of the trial, assessment of the secondary efficacy and safety parameters continued until 35 doses of the cream were applied. As such, the clinical study was designed to also mimic the dosing regimen intended to be applied in Helix’s planned U.S. Phase II/III and European Phase III pivotal efficacy trials for this indication. The clinical study was conducted under the direction of Prof. Dr. med. Achim Schneider, M.P.H., a world expert in the field of cervical cancer and Director of the Department of Gynecology at the Charité University Hospital in Berlin, Germany.

About CIN 1 and CIN 2

CIN 1 and CIN 2 are potentially precancerous, low-grade cervical lesions detectable upon colposcopic directed biopsy. There are approximately 1.3 million women diagnosed with CIN 1 or CIN 2 lesions each year in the U.S. alone, according to data from 2006 Consensus Guidelines in the American Journal of Obstetrics and Gynecology 2007; 340-345 and Kaiser Permanente Northwest Health Plan in the American Journal of Obstetrics and Gynecology (2004) 191, 105-13. Currently there are no pharmaceutical (non-surgical) treatments for women with CIN 1 or CIN 2 lesions. Available invasive/surgical techniques to treat CIN 1 or CIN 2 lesions are sometimes associated with serious unwanted side effects for patients including cervical complications with pregnancy and conception. For patients with CIN 1 or CIN 2 lesions, clinical management usually consists of protracted watchful waiting with frequent Pap smears, HPV testing, colposcopy and/or colposcopic directed biopsies, with invasive/surgical techniques generally utilized only in the case of long-term persistence and/or progression after a period of many months. A diagnosis of CIN 1 or CIN 2 leads to frequent physician visits, procedures, and psychosocial stress for the patient. The goal of developing Topical Interferon Alpha-2b is to provide a safe and effective treatment for CIN 1 or CIN 2 at the time of diagnosis, as a proactive alternative to today’s often protracted observational management approach.

About Topical Interferon Alpha-2b

Interferon alpha-2b is a potent cytokine that possesses antiviral, immunomodulatory and antiproliferative activities with activity against HPV. Topical Interferon Alpha-2b is a semi-solid formulation of recombinant interferon alpha-2b based on Helix’s Biphasix™ platform drug formulation technology. This technology involves the formation of biphasic lipid vesicles for use as a vehicle for administration of a biologically active material encapsulated within the lipid bilayers. Topical Interferon Alpha-2b has been developed as a cosmetically appealing cream dosage form that can be easily and conveniently self-applied intravaginally for the treatment of low-grade cervical lesions using a common vaginal applicator.

About Helix BioPharma Corp.

Helix BioPharma Corp. is a biopharmaceutical company focused on cancer therapy. The Company is actively developing innovative products for the prevention and treatment of cancer based on its proprietary technologies. Helix’s product development initiatives include its Topical Interferon Alpha-2b and its novel L-DOS47 new drug candidate. Helix is listed on the TSX, NYSE Amex and FSE under the symbol “HBP”. For more information, please visit www.helixbiopharma.com.

Forward-Looking Statements and Risks and Uncertainties

This News Release contains forward-looking statements and forward-looking information (collectively, “forward-looking statements”), within the meaning of applicable securities laws, regarding the Company’s plans for the development of Topical Interferon Alpha-2b in patients with low grade cervical lesions; the effectiveness of Topical Interferon Alpha-2b and its role as a therapeutic alternative; its planned designs for such proposed trial as well as its proposed European Phase III clinical trial; the development of Helix’s L-DOS47 and Topical Interferon Alpha-2b new drug candidates; and other information in future periods. Although Helix believes that the expectations reflected in such forward-looking statements are reasonable, such statements involve risks and uncertainties, and undue reliance should not be placed on such statements. Certain material factors or assumptions which have been applied in making such forward-looking statements, include, but are not limited to, assumptions regarding the safety and efficacy of Helix’s drug candidates; the timely receipt of necessary regulatory approvals and appropriate financing and strategic partner support; the timely and successful completion of the proposed U.S. and European clinical trials; and that the Company’s drug candidates will ultimately be successfully developed and commercialized. Important risk factors that could cause actual results to differ materially from these forward-looking statements include, without limitation, that the Company’s assumptions may prove to be incorrect; the Company’s continuing need for additional capital and for substantial funding beyond its current resources, as well as strategic partner support, to conduct the proposed U.S. and European trials, which are not assured; regulatory approvals to conduct the planned U.S. and European trials may be delayed or denied; the fact that results in earlier clinical studies may not be repeated in later clinical trials, and one or both of the planned clinical trials could fail; the failure of the European trial could have a material adverse impact on the U.S. trial and FDA approval; the need for further regulatory approvals, which are not assured; the Company’s dependence on performance by its third party providers of intellectual property, services and supplies, including without limitation, clinical trial services and supplies of drug product; the risk that Helix’s supplier of interferon alpha-2b may not continue to provide necessary supplies or exercise its commercialization option; the risk that the design or duration, or both, of the planned clinical trials may be different than currently intended; the potential need for further clinical trials beyond those mentioned in this news release which may not occur as planned or achieve expected results; product liability and insurance risks; risks and uncertainties related to research and development, including clinical trial and manufacturing risks; intellectual property risks, including without limitation, the risk that three patents for Topical Interferon Alpha-2b will expire in 2013 and no additional patent may be issued, which may negatively impact the further development or commercialization of the drug candidate; the effect of competition and the fact that there are a number of other companies developing potentially competitive products; uncertainties related to economic conditions; uncertainty whether L-DOS47 or Topical Interferon Alpha-2b will be successfully developed and commercialized; exchange rate risk; and the risk of changes in business strategy or development plans. Investors should consult the Company’s quarterly and annual filings, including its latest Form 20-F, with the Canadian and U.S. securities commissions at www.sedar.com and at www.sec.gov for additional information on these and other risks and uncertainties which may affect the Company. Investors are cautioned against placing undue reliance on forward-looking statements. Forward-looking statements are based on the beliefs, assumptions, opinions and expectations of Helix’s management at the time they are made, and Helix does not assume any obligation to update any forward-looking statement should those beliefs, assumptions, opinions or expectations change, except as required by securities law.

Filed Under: Hospitals and Health Systems, Public Health and Research

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