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Health Plan News

Timely Health Plan News and Commentary

Health Plan News
Home Archives for Public Health and Research

Public Health and Research News

Public health is the work of protecting the health of entire populations rather than individual patients: tracking disease, preventing outbreaks, promoting vaccination and screening, and studying what actually improves health outcomes. Research findings and public health data also drive coverage decisions, because health plans and regulators rely on evidence when they decide which services, screenings and treatments to cover.

What We Cover

This section covers public health developments and medical research with consequences for patients and health plans. That includes infectious disease, including COVID-19 and influenza; chronic conditions such as diabetes, heart disease, obesity and cancer; Alzheimer's disease and dementia; mental health and substance use; maternal and child health; and studies on health care costs, outcomes and access. We report on guidance from the Centers for Disease Control and Prevention (CDC) and the National Institutes of Health (NIH), and on peer-reviewed research and survey data.

How We Report Research

A single study rarely settles a question. When we report research, we identify who conducted and funded it, how large it was, and whether the findings are preliminary. This content is news and general information; it is not medical advice, and readers should discuss treatment decisions with a licensed clinician.

Research and public health news connects to our other sections. Drug approvals and vaccine coverage appear in Prescription Drugs and Pharmacy, preventive services coverage appears in Health Insurance Coverage, public health policy appears in Healthcare Policy and Law, and research on aging appears in Senior Care.

The latest public health and research news appears below, newest first.

SpectraScience WavSTAT Cancer Screening Technology Featured in MTI

Posted on July 27, 2010 Written by Editor

SOURCE: SpectraScience, Inc.

Company Named in the Top 50 Publicly Traded Biotech Firms by the American Registry

SAN DIEGO, CA–(Marketwire – July 27, 2010) –  SpectraScience, Inc. (OTCBB: SCIE), a San Diego based medical device company, today announced that it was named in the top 50 publicly Traded biotech firms by the American Registry. The award was recognized in the San Diego Daily Transcript. The company’s WavSTAT cancer Screening Technology was also recently featured in a cover story in the June 2010 issue of MTI, as a company to watch that is developing and advancing GI diagnostics and screening technologies. Other companies mentioned in the story include Fuji Photo Optical, Olympus Optical and Smiths Group.

According to the article about 20 million endoscopic procedures are performed annually in the U.S. and key factors driving growth in procedures includes the aging population and increasing prevalence of gastrointestinal disorders.

“One of the most exciting areas of technology development for gastroenterology is enhanced imaging modalities,” says author Staylo. “Researchers are continually looking for new ways to improve the accuracy and diagnostic utility of endoscopic screening methods.”

Jim Hitchin, CEO of SpectraScience, said, “We are pleased to have been named in the top 50 publicly traded biotech firms by the American Registry and to also have received significant attention at this year’s Digestive Disease Week (DDW), which led to this article highlighting our technology for the medical community. This shows that SpectraScience is making a name for itself with its state of the art technology.”

Benefits of WavSTAT Technology

  • Doesn’t require physical interpretation of screening results, but gives results in objective, standardized format
  • Both a therapeutic and diagnostic device so it can remove abnormal tissue at the exact location where it is detected
  • Enables physicians to identify where to biopsy rather than perform physical biopsies on a random basis
  • Capable of detecting dysplasia at deeper level than other image enhancement technologies

About WavSTAT
The WavSTAT Optical Biopsy System employs a spectrophotometry technique called Laser Induced Fluorescence (LIF) to optically illuminate and analyze tissue using a standard biopsy forceps. The System uses an optical fiber to send cool, safe UV laser light into suspected tissue, where the light reflects back to a computer at different frequencies, depending on the type of tissue. For example, in abnormal tissue, cells fluoresce differently than in healthy tissue and have a different “signature” that our system can interpret as either normal or abnormal. This can greatly assist the physician by providing an additional indication, displaying a green light for normal tissue and a red light for abnormal tissue. If the tissue appears abnormal, physicians can also use the WavSTAT System to biopsy the tissue.

The WavSTAT has FDA clearance to market for detecting pre-cancerous and cancerous tissue in the colon. The Company made several upgrades to its original technology before introducing it at this year’s DDW and launching it in the European market. SpectraScience is planning a full-scale market launch in the US in late 2010 or early 2011. Currently the Company holds approximately 60 patents for its optical probes and underlying technology.

Forward-Looking Statements
This news release contains forward-looking statements within the meaning of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended. These forward-looking statements involve risks and uncertainties that may cause SpectraScience’s actual results to differ materially from results discussed in forward-looking statements. Readers are urged to carefully review and consider the various disclosures made by SpectraScience in this news release, its most recent Form 10-K and in SpectraScience’s other reports filed with the Securities and Exchange Commission (“SEC”) that attempt to advise interested parties of the risks and factors that may affect SpectraScience’s business. These forward-looking statements are qualified in their entirety by the cautions and risk factors filed by SpectraScience in its annual report on Form 10-K and other documents.

About SpectraScience, Inc.
SpectraScience is a San Diego based medical device company that designs, develops, manufactures and markets spectrophotometry systems capable of determining whether tissue is normal, pre-cancerous or cancerous without physically removing tissue from the body. The WavSTAT Optical Biopsy System uses light to optically scan tissue and provide the physician with an immediate analysis. With FDA approval for sale in the U.S. and the CE Mark for the European Union, the WavSTAT System is the first commercially available product that incorporates this innovative technology for clinical use. The Company’s LUMA imaging technology has received FDA approval for an optical non-invasive system that is proven to more effectively detect cervical cancer precursors than conventional methods available in the market today.

Contact:
SpectraScience, Inc.
Jim Hitchin
Chief Executive Officer
(858) 847-0200 x201

Hayden Communications
Investor Relations
Todd Pitcher
(858)-518-1387

Filed Under: Health Technology and AI, Public Health and Research

Kalorama Comes Out With Seventh Edition of Its IVD Tome

Posted on July 26, 2010 Written by Editor

SOURCE: Kalorama Information

NEW YORK, NY–(Marketwire – July 26, 2010) –  Every two years, healthcare market research firm Kalorama Information releases the highly anticipated update to its industry leading report, “Worldwide Market for In Vitro Diagnostic Tests, 7th Edition.” In seven best-selling editions, Kalorama Information’s lead diagnostic analyst Shara Rosen has provided a total view of every aspect of the market for in vitro diagnostic (IVD) testing, in one complete volume.

“We’re very pleased to release this completely updated edition of our best-selling title,” said Bruce Carlson, publisher of Kalorama Information. “The idea behind our unique report is that the entire market can be captured in one volume and business planners can use it as a key reference.”

This go-to reference for the IVD industry reveals the trends that are impacting the field now, and provides a realistic forecast five years into the future for companies already participating in or considering entry into this growing industry. All of the major segments of clinical lab testing are covered.

Kalorama has reorganized the presentation of the IVD market in this latest edition in a manner that better reflects how the industry has evolved. For instance, there is an increased focus on lab automation. Due to a lack of trained lab technologists to run the more complex new set of molecular and histological tests and immunoassays, a proliferation of test and lab automation tools has been launched that remove precious human resources from mundane pre-analytical and sample tracking tasks to make time for more sophisticated ones.

“Worldwide Market for In Vitro Diagnostic Tests, 7th Edition” stands as a testament to the Kalorama methodology — real industry knowledge combined with numerous interviews of leading experts in the field and company executives, as well as an exhaustive review of the medical, business, and company literature. More than 900 pages and over 230 key company profiles reveal one vital piece of exclusive industry information after another. The report is available at: http://www.kaloramainformation.com/redirect.asp?progid=79375&productid=2613362.

About Kalorama Information
Kalorama Information supplies the latest in independent market research in the life sciences, as well as a full range of custom research services. We routinely assist the media with healthcare topics. Follow us on Twitter (http://www.twitter.com/KaloramaInfo) and LinkedIn (http://www.linkedin.com/groups?gid=2177845&trk=hb_side_g).

Filed Under: Public Health and Research

People With Diabetes Guaranteed Health Insurance Claims Rights

Posted on July 23, 2010 Written by Editor

SOURCE: American Diabetes Association

American Diabetes Association Issues Statement on New Insurance Claims Regulations

ALEXANDRIA, VA–(Marketwire – July 23, 2010) –  The American Diabetes Association applauds the new White House rule which will help people with diabetes and other chronic diseases appeal the denials of health insurance claims. This rule comes under the new Patient Protection and Affordable Care Act. The rules will help simplify the denial process and create consistency in all 50 states.

“In order to stay healthy, people with diabetes have to manage their disease with supplies like test strips, meters and insulin,” said Nash Childs, PE, Chair of the Board, American Diabetes Association. “Diabetes is a costly disease and without good coverage, the costs can make it difficult to manage properly. It is important that people with diabetes are treated fairly and given the opportunity to appeal any claims that are denied. The American Diabetes Association is grateful to the Obama administration for recognizing the need to make this available to everyone.”

The American Diabetes Association is leading the fight to stop diabetes and its deadly consequences and fighting for those affected by diabetes. The Association funds research to prevent, cure and manage diabetes; delivers services to hundreds of communities; provides objective and credible information; and gives voice to those denied their rights because of diabetes. Founded in 1940, our mission is to prevent and cure diabetes and to improve the lives of all people affected by diabetes. For more information please call the American Diabetes Association at 1-800-DIABETES (1-800-342-2383) or visit www.diabetes.org. Information from both these sources is available in English and Spanish.

Contact:
Christine Feheley
703-253-4374
[email protected]

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Filed Under: Health Insurance Coverage, Public Health and Research

VHA Study on Social Practices Reveals Manufacturers Can Help Lead Quality and Safety Efforts

Posted on July 21, 2010 Written by Editor

SOURCE: Medline Industries, Inc.

Observational Study of Clinicians Revealed Opportunities to Redesign Products to Better Support Clinician-Patient Interaction

MUNDELEIN, IL–(Marketwire – July 21, 2010) –  A new VHA case study whitepaper released by Medline Industries, Inc. details how the company used observational studies and context-based design to build human factors and social behaviors into its redesigned Foley Catheter Management tray.

The whitepaper, Social Practice and Clinicians’ Meaning of Urinary Catheter Insertions, showed that the redesigned tray significantly influenced the clinician’s ability to provide high quality care by creating a greater focus on providing patient comfort, maintaining sterile technique and decreasing the time of the entire insertion process. The observational study was comprised of three separate three-day observations of clinicians conducting catheterizations in the emergency department, medical/surgical floors and operating rooms at Providence Sacred Heart Medical Center and Children’s Hospital, Spokane, WA.

“Health care manufacturers are often overlooked when clinicians redesign clinical practices. Yet, the design of a product can be key to helping clinicians improve clinical performance and patient education,” said Trent Haywood, MD, JD, Senior Vice President of Clinical Performance and Chief Medical Officer for VHA and lead investigator. “For example, Medline chose to redesign the urinary catheter tray based upon the observational data uncovered in the clinical setting. Such design emphasis shows how manufacturers can be a key partner in quality and safety.” 

The unique partnership between Medline and the VHA research team highlights how industry vendors can partner with healthcare providers to develop a comprehensive system that incorporates proper procedures and social behaviors that are easy to adopt in every day practice.

Medline launched its ERASE CAUTI program, which is based on the same criteria the CDC used in developing their new CAUTI prevention guidelines, last fall. Soon after the tray’s introduction, Medline met with the VHA Clinical Performance team to discuss studying the tray and how it’s used in actual clinical practice. Emphasis was put on understanding the objectives of catheter insertions from the clinician’s perspective, clarifying the actual practice that unfolds and identifying areas where the catheter management system aided the clinician or failed to aid the clinician based upon the clinician’s perspective on the practice.

Findings summarized in a case study whitepaper showed that clinicians preferred the benefits of the single layer tray which did not require steps related to maneuvering and positioning with a two layer tray. They also preferred the change to swab sticks that decreased the number of steps in the prepping and cleansing of the perineum. Clinicians retained the patent-pending patient education card for the patient or placed it in location where the patient might review it — a departure from previously observed behavior where the education was discarded without much attention. Clinicians also used the full-colored photography packaging to better explain the procedure to patients.

“Chief Nursing Officers (CNOs) want to help their staff reduce variability in the procedures that are done so that the potential to make an error decreases,” said Connie Yuska, Medline’s Vice President of Clinical Services and a former CNO. “We redesigned the tray taking into account the interaction between the patient and the clinician and facilitate learning — things that challenge nursing leaders every day.”

The VHA whitepaper, as well as additional information on the ERASE CAUTI program, is available for download on Medline’s website at www.medline.com/erase.

About Medline Industries, Inc. 
Medline, the nation’s largest privately held manufacturer and distributor of healthcare products, manufactures and distributes more than 100,000 products to hospitals, extended-care facilities, surgery centers, home care dealers and agencies. Headquartered in Mundelein, Ill., Medline has more than 900 dedicated sales representatives nationwide to support its broad product line and cost management services.

Over the past five years, Medline has been the fastest-growing distributor of medical and surgical supplies in the U.S., serving as the primary distributor to over 450 major hospitals and healthcare systems. As a leading distributor, Medline offers a comprehensive array of consulting and management services encompassing the supply chain and logistics, utilization and standardization, business tools and enhanced reporting capabilities and on-staff clinicians.

Media Contacts:
Jerreau Beaudoin
(847) 643-3011
John Marks
(847) 643-3309

Filed Under: Hospitals and Health Systems, Public Health and Research

Datalliance VMI Customer, Bracco Diagnostics, Reviewed in Analyst Case Study on Healthcare Supply Chain

Posted on July 21, 2010 Written by Editor

SOURCE: Datalliance

Datalliance Identified as Vendor Managed Inventory Platform and Partner for Program

CINCINNATI, OH–(Marketwire – July 21, 2010) –  The Vendor Managed Inventory (VMI) strategy being developed by Bracco Diagnostics, a leading provider of contrast media and related equipment to hospitals and imaging centers, was recently featured in a Gartner report on supply chain innovations in the healthcare industry titled “Case Study: Bracco Diagnostics Leverages Datalliance for Downstream Customer Alliances” published July 8, 2010. 

The case study discusses Bracco Diagnostics’ success with the first phase of their VMI program within its own distribution network, as well as the company’s strategy to offer VMI to key customers as a value-added service to manage inventory, prevent stock-outs, and optimize procure-to-pay processes. 

Addressing the challenges to collaborative supply chain processes such as VMI in the healthcare industry, the report lists the following as lessons learned:

  • “Trading partners must be willing to collaborate on the development of improved business processes, increasing the level of trust by establishing bidirectional goals and measures.

  • Both the hospital and upstream supplier must start by thinking from the patient back. They should then develop innovative solutions to age-old challenges, such as inefficient transactions, bloated network inventories and less-than-optimal customer satisfaction.

  • There are a host of ancillary benefits to establishing robust VMI capabilities between trading partners. For example, the cycle time required to renegotiate supply contracts can be greatly reduced when both parties have a clear line of sight to expected volumes, supplier performance and customer satisfaction.”

The full report is available to Gartner clients at www.gartner.com/resId=1397037.

“VMI continues to expand in the healthcare industry and we’re proud to be working with forward-thinking suppliers like Bracco Diagnostics and others to leverage it as one means of bringing down the cost of patient care,” said Bob Jennings, Datalliance VP of Sales & Marketing. “This is another example of the many successful VMI programs within our customer community.” 

Earlier, Datalliance VMI was positively referenced in the AMR Research report titled “The Resurgence of Vendor Managed Inventory: A Landscape” published in October 2009. Visit www.datalliance.com/2009_dec_pr1.html for more information about that report, which is also available on the Gartner web site for companies with appropriate subscriptions. AMR Research is now part of Gartner.

About Datalliance
Datalliance is a leading provider of collaborative commerce services, and the world’s largest independent VMI service provider. Delivered via the Internet using the ‘Software as a Service’ (SaaS) model, Datalliance solutions make it easy for suppliers and their customers to establish sales and inventory management relationships that fully align business objectives, improve collaboration, and streamline supply chain operations. Datalliance manages billions of dollars in orders, millions of SKUs, and thousands of locations for leading Fortune 1000 companies in a number of industries. For more information about Datalliance, visit www.datalliance.com

Contact:
Brian Lindner
Datalliance
513-791-7272

Filed Under: Health Technology and AI, Public Health and Research

APHL Assists Haiti to Rebuild Devastated Lab System

Posted on July 20, 2010 Written by Editor

SOURCE: Association of Public Health Laboratories

SILVER SPRING, MD–(Marketwire – July 20, 2010) – A critically needed modular laboratory facility is en route to Port-au-Prince thanks to a collaboration between the Association of Public Health Laboratories (APHL) and International Relief Solutions, LLC (IRS). The APHL Haiti Field Laboratory Support Team provided technical assistance to International Relief Solutions, LLC (IRS) in planning and design of the new laboratory, which will replace the temporary tent facility that has served the nation’s largest hospital since the January earthquake. 

The 24′ by 36′ modular laboratory will be erected at L’Hôpital de l’Université d’État d’Haïti (HUEH). Since the earthquake, the number of patients being treated at HUEH has tripled from 14,000 per month to almost 42,000 thus increasing demands for laboratory testing. Due to extremely high temperatures and no air conditioning in the tent, automated testing requiring cooler temperatures, such as hematology and blood chemistry, are being run manually. The result is that the current testing capacity is only 25% of the daily demand. The modular lab facility is designed with infrastructure for work benches, heating, ventilation, plumbing and electrical services. With direct hookup to electrical and water supplies, the laboratory building will have the air conditioning necessary to meet the requirements of the many intricate and delicate tests that the laboratory technicians on scene perform routinely. The lab will arrive with the electrical system and plumbing pre-installed allowing for a quick start-to-finish set up of approximately four days.

APHL Senior Technical Consultant and Team Leader for the APHL Haiti Field Laboratory Support Team, Dave Doherty, coordinated this effort from start to finish. Following the earthquake, the Centers for Disease Control and Prevention requested and authorized Doherty and his team to assist all of the public health network laboratories in Haiti in getting testing services back up and running to support the enormous demands for medical care and treatment. 

Better lab facilities will improve testing services and also enable laboratory technologists to get back to work. According to Doherty, “Many well-trained technologists in Haiti are unable to work and provide testing services because of the loss of laboratory facilities to earthquake damage.”

It could be years before the permanent structures are rebuilt; the new modular lab serves as a long term solution. This initiative was a success due to the collaboration of willing and committed partners, each of whom brought essential resources and expertise to assure an effective solution for meeting a critical need in Haiti. Lives will be saved and illnesses treated effectively because of the efforts of APHL, IRS and CDC. Doherty modestly explains, “We were able to come through. APHL has always come through in Haiti.”

The Association of Public Health Laboratories is a national non-profit located in Silver Spring, MD, that is dedicated to working with members to strengthen governmental laboratories with a public health mandate. By promoting effective programs and public policy, APHL strives to provide public health laboratories with the resources and infrastructure needed to protect the health of US residents and to prevent and control disease globally.

Contact:
Michelle M. Forman
240.485.2793
Email Contact

Click here to see all recent news from this company

Filed Under: Public Health and Research

Pregnancy and Pre-Existing Diabetes

Posted on July 20, 2010 Written by Editor

SOURCE: American Diabetes Association

Diabetes Forecast With Information for Mothers-to-Be

ALEXANDRIA, VA–(Marketwire – July 20, 2010) – Pregnancy is a time of wonder and amazement — and for women with pre-existing diabetes, it is also a time for very extremely careful (and sometimes baffling) disease management. How do you plan for this? What risks are involved? What can you expect? The August issue of Diabetes Forecast, the consumer magazine of the American Diabetes Association, features articles about pregnancy with pre-existing diabetes to help you. With good care and planning, says Diabetes Forecast, women with either type 1 or type 2 diabetes can have safe pregnancies — and healthy babies.

Planning starts now. If you have diabetes and want to become pregnant, the first step should be visiting your doctor — or several doctors. Depending on your diabetes management, you may want to see an endocrinologist in addition to your ob-gyn for a pre-conception visit. When choosing your doctors, keep in mind that you may have appointments as often as twice a week, so try to find a physician that you are comfortable with and whose office you are comfortable getting to.

While pre-existing diabetes automatically puts your pregnancy in the high-risk category, healthy habits can lower the chance of problems for both mother and child. First and foremost, keep your blood glucose in check — in general, your A1C should be below 7 percent before you conceive. Your health care team may also want to discuss your weight, use of prenatal vitamins and other supplements, the status of any diabetes-related complications, and your current medications (such as ACE inhibitors or statins, which are not considered safe for use in pregnancy). Polycystic ovary syndrome is associated with type 2 diabetes, so for some women with diabetes, asking about fertility treatments may also be in order.

Once you become pregnant, your body’s changes can make blood glucose levels go from one extreme to the other. “I spent the entire first trimester with my face buried in the fridge,” says Kerri Sparling, 31, who has type 1 diabetes and whose daughter was born in April. “I was low all the time. It wasn’t until probably the second trimester that the insulin resistance kicked in. Everything I ate, the insulin didn’t cover it.” As your body changes through your pregnancy, so will its reactions to the elements you normally use to manage your blood glucose, so be prepared to communicate with your health care team often and make any necessary adjustments.

From pre-conception planning to integrating diabetes management into your birth plan and facing post-partum depression, having a baby can seem like an overwhelming task for women with diabetes, and yet, many women with diabetes find they have the best glucose control of their life during pregnancy. “This was so, so important to me that I was willing to do whatever to make sure she came out right,” says Sparling. “It’s so worth it.” Find more advice, explanations and insight about what to expect in the August issue of Diabetes Forecast.

This issue of Diabetes Forecast also features:

  • A Birthday Challenge: Marking 40 years with 40 races for ADA’s Team Diabetes
  • Drinking Calories: How you hydrate yourself makes a difference
  • A Serious Subject: Dealing with erectile dysfunction

Diabetes Forecast has been America’s leading diabetes magazine for more than 60 years, offering the latest news on diabetes research and treatment to provide information, inspiration and support to people with diabetes. 

The American Diabetes Association is leading the fight to stop diabetes and its deadly consequences and fighting for those affected by diabetes. The Association funds research to prevent, cure, and manage diabetes; delivers services to hundreds of communities; provides objective and credible information; and gives voice to those denied their rights because of diabetes. Founded in 1940, its mission is to prevent and cure diabetes and to improve the lives of all people affected by diabetes. For more information, please call the American Diabetes Association at 1-800-DIABETES (1-800-342-2383) or visit www.diabetes.org. Information from both these sources is available in English and Spanish.

Contact:
Dayle Kern
[email protected]
(703)549-1500 x2290

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Filed Under: Public Health and Research

iData Research: Rapid Growth of NuVasive’s XLIF(R) for the Treatment of Back Pain Fuels MIS Spinal Fusion Procedures to Triple by 2016

Posted on July 20, 2010 Written by Editor

VANCOUVER, BRITISH COLUMBIA–(Marketwire – July 20, 2010) – According to new spinal implant reports by iData Research (www.idataresearch.net), the leading global authority in medical device and pharmaceutical market research, the U.S. market for spinal implants is estimated to exceed $8 billion by 2016, while the MIS spinal implant market is estimated to reach over $3 Billion. In addition, rapid growth in artificial disc use will fuel the spinal motion preservation market to increase six-fold by 2016.

While many have predicted the cannibalization of spinal fusion procedures by motion preservation, iData’s report reveals healthy growth in the fusion market driven by a consistent rise in minimally invasive surgical (MIS) interbody procedures, the market for which will triple by 2016.

“Lateral lumbar interbody fusion, such as NuVasive’s XLIF(R) (NASDAQ:NUVA), is the most rapidly increasing MIS interbody fusion procedure,” says Dr. Kamran Zamanian, CEO of iData.

Despite growth in spinal fusion, the competing spinal motion preservation market, which includes cervical artificial discs, is also expected to experience strong growth. Reimbursement policies for motion preservation devices are expected to continue to drive this market.

“The cervical artificial disc segment is aiding strong growth in the spinal motion preservation market,” says Dr. Zamanian. “Companies such as DePuy, Medtronic and Synthes are leading the market, while many competitors such as Cervitech, Globus, NuVasive, SpinalMotion, and Zimmer are expected to emerge into this segment in the next few years.”

iData’s global report series on the “Markets for Spinal Implants & VCF 2010” and the “Markets for Minimally Invasive Spinal Devices 2010” also covers VCF, spinous process fixation, facet fixation and MIS pedicle screws.

For more information, register free on iData’s website at: http://www.idataresearch.net/idata/registration.php

About iData Research

iData Research (www.idataresearch.net/idata/discoveridata.php) is an international market research and consulting group focused on providing market intelligence for medical device and pharmaceutical companies.

Filed Under: Health Technology and AI, Public Health and Research

Cystinosis Research Foundation Names Three Pre-Eminent Scientists to 2010 Scientific Panel Advising Foundation

Posted on July 20, 2010 Written by Editor

SOURCE: Cystinosis Research Foundation

IRVINE, CA–(Marketwire – July 19, 2010) –  The Cystinosis Research Foundation has named three prominent researchers to its Scientific Review Board, which reviews and recommends applications for grants to study the rare and fatal metabolic disease and develop new treatments and a cure. Cystinosis afflicts about 2,000 persons, mostly children, worldwide.

Joining the CRF’s Scientific Review Board are: Drs. Stephanie Cherqui of The Scripps Research Institute, La Jolla, Calif.; Allison Eddy of the University of Washington, Seattle, Wash. and Francisco Emma of the Bambino Gesù Children’s Hospital in Rome.

Leaving the CRF’s Scientific Review Board and retiring from a historic career in metabolic disease research is Dr. Jerry Schneider, M.D., who was Professor of Pediatrics and Dean for Academic Affairs at the University of California, San Diego. He is a developer of the two breakthrough treatments for cystinosis, which he began studying in 1965.

“We are fortunate to have such pre-eminent scientists advising us on funding cystinosis research. Over the years, they have made valuable contributions to cystinosis research and are committed to finding improved treatments and a cure,” said Nancy Stack, President and co-founder of the CRF.

She added that the lifelong research on cystinosis by Dr. Schneider “has brought us to the threshold of a new treatment and a cure. He has encouraged and mentored new researchers who now, in turn, have dedicated their careers to cystinosis. Cystinosis patients and their families owe him eternal gratitude,” Stack said.

Dr. Cherqui, Ph. D., an assistant professor at The Scripps Research Institute, is credited with developing a breakthrough cell and gene therapy regimen that has improved cystinosis in mice. She is a member of the CRF Gene Therapy Consortium. Dr. Cherqui worked in Paris with a group led by Dr. Corinne Antignac that identified the cystinosis CTNS gene. Her 2002 doctoral thesis was on molecular studies of cystinosis and the generation of the mouse model for cystinosis. Dr. Cherqui is a member of the American Society of Gene and Cell Therapy. She has authored 12 publications on cystinosis, including a cover article in the October issue of the scientific journal “Blood.”

Dr. Eddy, M.D., professor of pediatrics at the University of Washington, is internationally recognized for her work on the cellular and molecular basis of kidney fibrosis and progressive kidney disease. She is the director of the Tissue and Cell Biology Research Center at Seattle Children’s Research Institute and in 2009 was elected to the Council of the International Society of Nephrology. Dr. Eddy holds the Robert O. Hickman Endowed Chair in Pediatric Nephrology at the University of Washington. She is a graduate of the McMaster University Medical School in Canada.

Dr. Emma, M.D., is head of Pediatric Nephrology at the Bambino Gesù Children’s Hospital in Rome, Italy, and president of the Italian Society of Pediatric Nephrology. Dr. Emma’s laboratory research on cystinosis has been focused on studying cell mechanisms that regulate the expression of the CTNS gene and different isoforms of the cystinosin protein. He recently began studying the therapeutic potentials of stem cells for treatment of cystinosis with the support of the CRF. Dr. Emma received his medical degree from the Catholic University of Louvain, Brussels, Belgium. He trained at Children’s Hospital, Harvard Medical School, Boston, Mass.

Cystinosis is a metabolic disease that slowly destroys every organ in the body, including the liver, kidneys, eyes, muscles, thyroid and brain. There is a medicine that prolongs the children’s lives, but there is no cure. Most cystinosis sufferers succumb to the disease or its complications by age 40.

In patients with cystinosis, the amino acid cystine accumulates in the tissue due to the inability of the body to transport cystine out of the cell. This causes development of crystals, resulting in early cell death. There is a medication but, as yet, no cure for the disease.

Twice a year the CRF announces worldwide calls to the scientific community for research proposals. Since 2003, the CRF’s Scientific Review Board has played a key advisory role for 78 research grants totaling $11.8 million to scientists studying cystinosis in North America and Europe. Currently, there are 48 CRF-funded studies underway along with 13 CRF research fellows in the United States, Canada, France, Italy, Belgium, Ireland, Germany and The Netherlands.

The CRF is the leading funding source for cystinosis research. The foundation recently approved requests totaling $988,759 for seven new grants. Every dollar raised by the CRF is committed for medical research. Administrative costs are privately underwritten.

Nancy Stack and her husband, Geoffrey, a managing director of the SARES REGIS Group, an Irvine real estate company, have a daughter, Natalie, 19, with cystinosis.

For more information about Cure Cystinosis International Registry and the Cystinosis Research Foundation of Irvine, Calif., call Zoe Solsby at (949) 223-7610 or visit www.cystinosisresearch.org.

Contact:
Art Barrett
(714) 309-3700
Zoe Solsby
(949) 223-7610

Filed Under: Public Health and Research

Neuronetrix Showcases New Cognitive Testing Device at the Alzheimer’s Association Annual Meeting

Posted on July 19, 2010 Written by Editor

SOURCE: Neuronetrix, Inc.

LOUISVILLE, KY–(Marketwire – July 19, 2010) –  This week at ICAD 2010, Neuronetrix for the first time publicly demonstrated their COGNISION™ System, an innovative platform which enables objective assessment of cognitive function. The demonstration focused on the COGNISION™ System’s ability, using a non-invasive technology called event-related potentials (ERP), to accurately measure the cognitive performance of a patient’s brain.

The demonstration was particularly important in light of a report presented by a select group of Alzheimer’s specialists from the National Institute on Aging (NIA) and the Alzheimer’s Association which proposed new diagnostic guidelines for Alzheimer’s disease. The report titled, “Redefining Alzheimer’s Disease,” proposes a new understanding of the disease which more closely matches clinical progression with a range of disease biomarkers. It also includes patients who meet clinical and cognitive criteria but who are negative for certain genetic, molecular, or structural biomarkers. “This is a tremendous opportunity for Neuronetrix as our test directly measures the electrical activity associated with cognition and is independent of biochemical pathways,” said Mauktik Kulkarni, Director of Research and Clinical Studies for Neuronetrix.

The new criteria also facilitates the tremendous drug development effort for disease modifying therapies for Alzheimer’s. Drug companies will now have a more reliable way of identifying those Alzheimer’s sufferers who might benefit from new drug therapies. The criteria also lays the groundwork for using positive changes in certain biomarkers as measures of drug effectiveness. “Because the COGNISION™ System could be used to measure progressive cognitive as well as drug response, we had tremendous interest from several of the large pharmaceutical companies at the conference,” said K.C. Fadem, Chief Operating Officer for Neuronetrix.

Neuronetrix previously completed a pilot clinical study with Alzheimer’s patients and healthy controls at the Sanders-Brown Alzheimer’s Disease Center at the University of Kentucky. The study validated the high data quality and ease-of-use of the COGNISION™ System in a clinical setting. Neuronetrix will soon be initiating a large multi-center clinical study which will validate their ERP biomarkers as an accurate and reliable measure of cognitive impairment. The company is planning a longitudinal follow up study which will validate their ERP biomarkers as a measure of progressive cognitive decline. “Because of the low cost, ease of use, and measurement potential of the COGNISION™ test, ERP testing could become a standard of care for those patients who develop cognitive disorders such as Alzheimer’s disease,” said K.C. Fadem.

About Alzheimer’s Disease
Alzheimer’s disease is a chronic neurodegenerative disease of the brain which eventually leads to death. Today, Alzheimer’s disease affects over five million Americans with 500,000 new cases reported each year. Medicare/Medicaid spending exceeds $100 billion on beneficiaries with Alzheimer’s and other dementias.

About Neuronetrix
Neuronetrix is an emerging med-tech company focused on revolutionizing the diagnosis of patients with neurologic disorders by providing accurate and meaningful diagnostic information to physicians early in the disease process.

Information about Neuronetrix is available at http://www.neuronetrix.com or by contacting K.C. Fadem at [email protected] or (502) 561-9040.

Filed Under: Hospitals and Health Systems, Public Health and Research

Study on Social Practices Reveals Manufacturers Can Help Lead Quality and Safety Efforts

Posted on July 19, 2010 Written by Editor

SOURCE: Medline Industries, Inc.

Observational Study of Clinicians Revealed Opportunities to Redesign Products to Better Support Clinician-Patient Interaction

MUNDELEIN, IL–(Marketwire – July 19, 2010) –  A new VHA case study whitepaper released today by Medline Industries, Inc. details how the company used observational studies and context-based design to build human factors and social behaviors into its redesigned Foley Catheter Management tray.

The whitepaper, Social Practice and Clinicians’ Meaning of Urinary Catheter Insertions, showed that the redesigned tray significantly influenced the clinician’s ability to provide high quality care by creating a greater focus on providing patient comfort, maintaining sterile technique and decreasing the time of the entire insertion process. The observational study was comprised of three separate three-day observations of clinicians conducting catheterizations in the emergency department, medical/surgical floors and operating rooms at Providence Sacred Heart Medical Center and Children’s Hospital, Spokane, WA.

“Health care manufacturers are often overlooked when clinicians redesign clinical practices. Yet, the design of a product can be key to helping clinicians improve clinical performance and patient education,” said Trent Haywood, MD, JD, Senior Vice President of Clinical Performance and Chief Medical Officer for VHA and lead investigator. “For example, Medline chose to redesign the urinary catheter tray based upon the observational data uncovered in the clinical setting. Such design emphasis shows how manufacturers can be a key partner in quality and safety.” 

The unique partnership between Medline and the VHA research team highlights how industry vendors can partner with healthcare providers to develop a comprehensive system that incorporates proper procedures and social behaviors that are easy to adopt in everyday practice.

Medline launched its ERASE CAUTI program, which is based on the same criteria the CDC used in developing their new CAUTI prevention guidelines, last fall. Soon after the tray’s introduction, Medline met with the VHA Clinical Performance team to discuss studying the tray and how it’s used in actual clinical practice. Emphasis was put on understanding the objectives of catheter insertions from the clinician’s perspective, clarifying the actual practice that unfolds and identifying areas where the catheter management system aided the clinician or failed to aid the clinician based upon the clinician’s perspective on the practice.

Findings summarized in a case study whitepaper showed that clinicians preferred the benefits of the single layer tray which did not require steps related to maneuvering and positioning with a two layer tray. They also preferred the change to swab sticks that decreased the number of steps in the prepping and cleansing of the perineum. Clinicians retained the patent-pending patient education card for the patient or placed it in location where the patient might review it — a departure from previously observed behavior where the education was discarded without much attention. Clinicians also used the full-colored photography packaging to better explain the procedure to patients.

“Chief Nursing Officers (CNOs) want to help their staff reduce variability in the procedures that are done so that the potential to make an error decreases,” said Connie Yuska, Medline’s Vice President of Clinical Services and a former CNO. “We redesigned the tray taking into account the interaction between the patient and the clinician and facilitate learning — things that challenge nursing leaders every day.”

The VHA whitepaper, as well as additional information on the ERASE CAUTI program, is available for download on Medline’s website at www.medline.com/erase.

About Medline Industries, Inc. 

Medline, the nation’s largest privately held manufacturer and distributor of healthcare products, manufactures and distributes more than 100,000 products to hospitals, extended-care facilities, surgery centers, home care dealers and agencies. Headquartered in Mundelein, Ill., Medline has more than 900 dedicated sales representatives nationwide to support its broad product line and cost management services.

Over the past five years, Medline has been the fastest-growing distributor of medical and surgical supplies in the U.S., serving as the primary distributor to over 450 major hospitals and healthcare systems. As a leading distributor, Medline offers a comprehensive array of consulting and management services encompassing the supply chain and logistics, utilization and standardization, business tools and enhanced reporting capabilities and on-staff clinicians.

Media Contacts:
Jerreau Beaudoin
(847) 643-3011
John Marks
(847) 643-3309

Filed Under: Hospitals and Health Systems, Public Health and Research

Casting Call: All Breast Cancer Survivors Who Want to Be Part of the Next Pink Glove Dance Video

Posted on July 16, 2010 Written by Editor

SOURCE: Medline Industries, Inc.

Video Shoot Takes Place Saturday, July 24, 3:00 p.m., Just East of Fort Point Pier

MUNDELEIN, IL–(Marketwire – July 16, 2010) – Medline Industries, Inc., the company who produced the original Pink Glove Dance, is looking for breast cancer survivors in the San Francisco area who want to be part of the next Pink Glove Dance video. The original video has become an internet sensation, generating almost 11 million views on YouTube since its release last November. The video features healthcare workers at Providence St. Vincent Medical Center in Portland, Ore. dancing while wearing pink gloves.

When and where will it be?
Filming will take place Saturday, July 24th at 3:00 p.m. in the big field just east of Fort Point Pier, with the Golden Gate Bridge in the background.

What are the qualifications to participate?
Participants need to be breast cancer survivors and willing to dance wearing pink gloves. No special dancing skills required. A choreographer will be there to teach simple routines.

How long will it take?
Approximately two hours.

How do I sign up?
Details of the video shoot and registration can be found online at www.pinkglovedance.com/sign-up.
Although participants can just show up on the day of the event, participants are encouraged to register online. 

Details of the day, and any weather updates, will be posted on www.pinkglovedance.com.

Why is this video being made?
The first video was created to help spread the word about breast cancer awareness and the importance of the healthcare worker who takes care of breast cancer patients. It was so successful and generated so much positive attention that hospitals around the country called to see if they could be part of the next video. So the idea of a sequel was developed that not only included hospital workers but breast cancer survivors too. 

Why pink exam gloves?
As a way to extend Medline’s breast cancer awareness campaign, the company developed a pink glove called Generation Pink™. Gloves are also the first point of contact between the healthcare worker and the patient. And, the fact the glove is pink, Medline hoped would get people talking about breast cancer. When the gloves were launched in October, Medline committed to donating $1 of every case purchased to the National Breast Cancer Foundation to fund mammograms for individuals who cannot afford them. In the past five years, Medline has donated almost $500,000 to the National Breast Cancer Foundation. 

Media Contact:
John Marks
(847) 643-3309

Jerreau Beaudoin
(847) 643-3011

Filed Under: Public Health and Research

New Study Proves Care by Podiatrists Dramatically Decreases Lower Limb Amputation

Posted on July 15, 2010 Written by Editor

SOURCE: American Podiatric Medical Association

Research Results to be Presented at APMA’s 98th Annual Scientific Meeting

BETHESDA, MD–(Marketwire – July 15, 2010) –  

*MEDIA NOTE: Study will be presented at the Washington State Convention Center on Saturday, July 17, at 7:30am.

Essential foot care by a podiatrist has now been statistically proven to reduce hospitalization and amputation in adults with diabetes, according to a first of its kind study conducted by Thomson Reuters. The study will be presented by Vickie R. Driver, MS, DPM, during the American Podiatric Medical Association’s (APMA) 98th Annual Scientific Meeting in Seattle, July 15-18, 2010. The presentation will highlight the dramatic impact that as few as one visit to a podiatrist can have on patients with diabetes.

The study, which was sponsored by APMA, examined records for more than 32,000 patients with diabetes, ages 18-64, and compared health and risk factors for those who had podiatry visits to those who did not. Researchers found that care by a podiatric physician (defined as at least one preventative, pre-ulcer visit) was associated with a nearly 29 percent lower risk of amputation and 24 percent lower risk of hospitalization. Diabetic foot complications are the leading cause of non-traumatic lower limb amputation in the U.S. 

“The results of this study undeniably support visits to a podiatrist being critical to a diabetes patient’s health and well being,” said APMA member Dr. Driver. “No longer can care by a podiatrist be considered optional for those with diabetes, and the earlier a podiatrist is included in the diabetes management team, the better quality of life for the patient and greater health-care cost savings for all involved. This study clearly allows us to understand both the clinical and economic value of a podiatrist, in the team approach to saving diabetic patients’ feet.”

The study was conducted using Thomson Reuters’ MarketScan Research Databases, which house fully integrated, de-identified health-care claims data extensively used by researchers to understand health economics and outcomes. Studies based on MarketScan data have been published in more than 130 peer-reviewed articles in the past five years.

Lead researcher Teresa Gibson, PhD, director of health outcomes research at Thomson Reuters said, “Using the MarketScan Databases, we statistically matched patients with diabetes and foot ulcers who had visited a podiatrist with like patients who had not. The analysis of the data indicates that patients who had seen a podiatrist in the year prior to the onset of a foot ulcer had significantly lower rates of any amputation and hospitalization than those who had not.”

For additional information on the study, visit www.apma.org/diabetesstudy.

Media interested in attending the presentation during the APMA 98th Annual Scientific Meeting should contact Angela Berard at [email protected] or 301-861-9342.

Founded in 1912, the American Podiatric Medical Association (APMA) is the nation’s leading and recognized professional organization for doctors of podiatric medicine (DPMs). DPMs are podiatric physicians and surgeons, also known as podiatrists, qualified by their education, training and experience to diagnose and treat conditions affecting the foot, ankle and structures of the leg. The medical education and training of a DPM includes four years of undergraduate education, four years of graduate education at an accredited podiatric medical college and two or three years of hospital residency training. APMA has 53 state component locations across the United States and its territories, with a membership of close to 12,000 podiatrists. All practicing APMA members are licensed by the state in which they practice podiatric medicine. For more information, visit www.apma.org.

Thomson Reuters is the world’s leading source of intelligent information for businesses and professionals. We combine industry expertise with innovative technology to deliver critical information to leading decision makers in the financial, legal, tax and accounting, healthcare and science and media markets, powered by the world’s most trusted news organization. With headquarters in New York and major operations in London and Eagan, Minnesota, Thomson Reuters employs 55,000 people and operates in over 100 countries. For more information, go to www.thomsonreuters.com.

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Filed Under: Hospitals and Health Systems, Public Health and Research

Implementation of the Affordable Care Act Must Lead to Adequate Diabetes Screening

Posted on July 15, 2010 Written by Editor

SOURCE: American Diabetes Association

ALEXANDRIA, VA–(Marketwire – July 14, 2010) –  On Wednesday, July 14, the Obama Administration joined medical professionals and leaders from the health community to announce preventive health care coverage made available under the Affordable Care Act. Under this act, new insurance plans are required to provide preventive care without cost-sharing, which will remove financial barriers for many Americans for preventive services that can help alleviate disease and reduce costs. 

The American Diabetes Association believes that while this is laudatory, relying exclusively on the United States Preventive Services Task Force (USPSTF) “A and B” recommendations, will not lead to adequate screening of patients at risk for diabetes. Blood glucose screening is one of the most essential tools for detecting diabetes and something that should be part of a basic package of benefits and services. 

Under the new rule, asymptomatic adults with sustained high blood pressure will have access to diabetes screening and adults and children will have access to obesity screening and counseling through their clinician at no cost. Ensuring that patients with other risk factors, such as a family history of diabetes or who are obese, also have access to preventive screenings at low or no cost will allow for earlier diagnosis and subsequent prevention of dangerous and costly complications. 

Through implementation of the Affordable Care Act we must ensure that patients at high risk of diabetes are screened for the disease when they see their primary care physician. Nearly 6 million of the 24 million Americans living with diabetes have not been diagnosed. There is an additional 57 million Americans with pre-diabetes, and nearly 93 percent do not know it. If left untreated, diabetes leads to costly and dangerous complications such as blindness, amputation, heart disease, and kidney disease. Relying solely on the USPSTF recommendation, which gives an “I” statement to blood glucose screening for any asymptomatic patient not experiencing high blood pressure, will continue to leave millions of Americans undiagnosed and in danger of facing otherwise avoidable health complications such as blindness, amputation, heart disease, and kidney disease.

We are supportive of the provisions that cover obesity screening and other diabetes-related prevention services. We look forward to working with the Obama Administration and Congress to ensure that people have access to diabetes screenings, as well as to the preventive services that help to manage the disease and prevent complications following diagnosis.

American Diabetes Association guidelines (below) recommend screening for individuals who meet the common risk factors for diabetes. These criteria are consistent with those used in scientific studies of diabetes prevention.

  • All adults who are overweight and have additional risk factors:
    • Physical inactivity
    • First degree relative with diabetes
    • Women diagnosed with gestational diabetes or who delivered a baby weighing > 9 lb.
    • Hypertension (high blood pressure) or cholesterol abnormality
    • Other clinical conditions associated with resistance to the effects of insulin
  • In the absence of the above criteria, testing should begin at age 45 years
  • If results are normal, testing should be repeated at least at 3 year intervals, with consideration of more frequent testing depending on initial results and risk status.

The American Diabetes Association believes that targeted diabetes screening as outlined by the our recommendations and supported by the National Institute of Diabetes and Digestive and Kidney Diseases, and are in line with risk factors recommended by the Centers for Disease Control and Prevention must be considered a covered preventive service. Doing so will meet the dual goals of the Affordable Care Act, that is emphasizing prevention and reining in healthcare costs.

The American Diabetes Association is leading the fight to stop diabetes and its deadly consequences and fighting for those affected by diabetes. The Association funds research to prevent, cure and manage diabetes; delivers services to hundreds of communities; provides objective and credible information; and gives voice to those denied their rights because of diabetes. Founded in 1940, our mission is to prevent and cure diabetes and to improve the lives of all people affected by diabetes. For more information please call the American Diabetes Association at 1-800-DIABETES (1-800-342-2383) or visit www.diabetes.org. Information from both these sources is available in English and Spanish.

Contact:
Christine Feheley
703 253-4374

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Filed Under: Public Health and Research

www.DrRidwan.com: Urologist Dr. Ridwan Shabsigh, MD Provides Action Tools for Men’s Health in His Online Medical Advice Talk Show

Posted on July 13, 2010 Written by Editor

SOURCE: DrRidwan.com

NEW YORK, NY–(Marketwire – July 13, 2010) – Maimonides Medical Center Urologist Dr. Ridwan Shabsigh, director of the Division of Urology, created his “Ask The Doctor” medical advice talk show to help bridge the gap of men’s healthcare information in a simple-to-understand format. His online health talk show, “The Dr. Ridwan Show” delivers accurate and usable health information on common men’s health questions.

Along with an elite panel of experts, Drs. Harry Fisch, Michael Perelman and Richard Sadovsky, the group provides reliable health information to common men’s health questions. Ridwan and his medical panelists provide unique insights and advice that support the show’s tagline, “Health information you can use.” The panelists discuss a hot topic per episode in men’s health such as heart disease, prostate cancer, testosterone deficiency and erectile dysfunction.

Each episode of Dr. Ridwan’s unique online doctor consultation show concludes with helpful action tools that incite viewers to take positive actions for their health. The most helpful action tool is a men’s health calculator. This health risk calculator helps to raise awareness and motivate men to access health care services and pursue healthier lifestyles.

This men’s health calculator is not an absolute measure of risk or a substitute for professional health advice, but it helps men to assess their risk of having hypertension (high blood pressure), hyperlipidemia (high cholesterol), diabetes and/or coronary artery disease. The viewer can answer basic questions on health status, erectile dysfunction, relationships, and waist size to help determine health risk.

Other helpful tips provided on Dr. Ridwan’s doctor advice show:

  • Avoid abdominal obesity to prevent heart and vascular disease risk
  • Men’s health preventive ideas
  • Get annual checkup and prostate screenings
  • Ask for urologist referral if abnormal urinary symptoms exist
  • Men should work with partners to improve health
  • Review health risks and reduce these factors
  • Watch for sexual problems
  • Be aware of testosterone deficiency symptoms

By providing answers to medical questions online, Dr. Ridwan hopes to reduce the need for unnecessary procedures and tests. “In these times of healthcare reform, by educating my viewers, I hope to make them be more proactive in monitoring their health,” said Ridwan. “This way they won’t have to make unnecessary trips to the emergency room for something that can be taken care of in advance or prevented.”

Contact:

Dr. Ridwan Shabsigh
Ph: 718-283-7746
http://www.DrRidwan.com

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Filed Under: Public Health and Research

Coma saludable para lucir bien este verano

Posted on July 13, 2010 Written by Editor

SOURCE: American Diabetes Association

La Asociación Americana de la Diabetes ofrece un consejero de comida para ayudarle a prepararse para el verano y el futuro

ALEXANDRIA, VA–(Marketwire – July 13, 2010) – Prepararse para el verano significa sembrar
los jardines, limpiar el asador y salir a comprar trajes de baño. Los
productos del verano y las opciones para cocinar también significan que la
temporada es una oportunidad para mejorar sus hábitos alimenticios. La
Asociación Americana de la Diabetes anunció hoy sobre una herramienta en
línea de nutrición en español y en inglés que le ayudará a prepararse para
la temporada.: MiConsejerodeComida™ http://tracker.diabetes.org/es/.

MiConsejerodeComida tiene características nuevas y mejoradas que le
permitirán a las personas a mantener un registro de sus comidas diarias,
sustituir alternativas más saludables para recetas o en el plato. Las
personas con diabetes, enfermedades cardiacas, enfermedad renal, alta
presión arterial, alto colesterol y aquellas personas que quieren bajar de
peso pueden utilizar MiConsejerodeComida para encontrar información
nutricional sobre calorías, carbohidratos, sodio, grasa y colesterol.

“Hacer pequeños cambios al tiempo de la comida puede tener un impacto
positivo en su salud,” comentó Lorena Drago, RD, CDE, voluntaria de la
Asociación Americana de la Diabetes. “MiConsejerodeComida le puede enseñar
hacer alternativas saludables, crear metas y registrar lo que come. Si
pierde solamente 10 o 15 libras, usted puede ponerle alto a la diabetes al
prevenir o retrasar la diabetes tipo 2 o sus complicaciones…”

Las características nuevas incluyen:

  • Versión en español – Todo el sitio web está disponible ahora en
    español. La prevalencia de la diabetes es de 2 a 4 veces más alta entre
    los hispanos/latinos.
  • Regístrelo – Usted puede crear sus metas para calorías,
    carbohidratos, sodio, grasa saturada y fibra y compararlas con lo que
    actualmente está comiendo y lo que quisiera comer. Este análisis le permite
    hacer opciones más saludables para reducir el consume de sodio y grasa
    saturada o para mantener su consumo de carbohidratos consecuente en el día
    a día.

Las características actualizadas incluyen:

  • Alternativa saludable – Esta característica, exclusiva a
    MiConsejerodeComida™, le permite buscar comidas más saludables. Por
    ejemplo, si busca una alternativa más saludable para la carne de res
    molida para su receta favorita de hamburguesa, le proporcionaría otras
    opciones de carne molida tales como, pavo molido o alternativas
    vegetarianas. El algoritmo, que es basado en investigaciones recientes,
    toma en cuenta 13 nutrientes diferentes para recomendar la mejor
    alternativa basándose en sus selecciones.
  • Análisis de recetas – Analice sus recetas favoritas con nuestra
    función de Crear un plato. Usted puede solicitar opciones más saludables
    para los ingredientes de su receta para hacer que un viejo favorito sea un
    favorito saludable. Sus propias recetas pueden ser guardadas en su
    recetario e importadas a la herramienta de registro y los ingredientes
    pueden ser agregados a su lista de compras.
  • Crear un plato – Los tamaños de las porciones han sido
    incrementadas para reunir sus preferencias al utilizar medidas simples de
    cocina.
  • Navegación simple – Esto le permite buscar y comparar opciones
    de comidas con más facilidad.

“Los tamaños de las porciones en MiConsejerodeComida son basadas en 15
gramos de carbohidratos, lo cual hace que sea más fácil para las personas
con diabetes y sus cuidadores a contar carbohidratos. MiConsejerodeComida
también tiene información sobre fósforo y potasio, 2 nutrientes importantes
que se deben vigilar para las personas con enfermedad renal, comentó Lorena
Drago. “Sin importar para qué, MiConsejerodeComida puede ayudar a cualquier
persona a prepararse para el verano al enseñarle como hacer mejores
opciones de comida.”

La Asociación Americana de la Diabetes es líder en la lucha para ponerle
alto a la diabetes y sus consecuencias fatales y lucha por las personas
afectadas por esa enfermedad. La Asociación financia la investigación a fin
de prevenir, curar y controlar la diabetes; ofrece servicios para cientos
de comunidades; suministra información objetiva y verosímil; y da voz a
aquellas personas privadas de sus derechos como consecuencia de la
diabetes. La Asociación se fundó en 1940. Nuestra misión es prevenir y
curar la diabetes, así como mejorar la vida de todas las personas afectadas
por esa enfermedad. Para más información llamar al 1-800-DIABETES
(342-2383) o visitar www.portufamilia.org. Información sobre ambas fuentes
se encuentra disponible en inglés o en español.

Filed Under: Public Health and Research

Eat the Zucchini, Wear the Bikini

Posted on July 13, 2010 Written by Editor

SOURCE: American Diabetes Association

American Diabetes Association Offers Completely Updated Personal Food Advisor to Help You Survive Summer and Beyond

ALEXANDRIA, VA–(Marketwire – July 13, 2010) –  Summer means gardening, grilling, and swimming at the pool. Summer’s produce and expanded cooking options also mean the season is an opportunity to improve your eating habits. The American Diabetes Association announced today a completely revised online nutrition tool in English and Spanish to help you get ready for the season: MyFoodAdvisor™ (www.diabetes.org/MyFoodAdvisor).

The award-winning MyFoodAdvisor has new and expanded features that allow people to track their daily meals, substitute healthier alternatives in recipes or on the plate, and browse recipes. People with diabetes, heart disease, kidney disease, high blood pressure, high cholesterol and those looking to lose weight can use MyFoodAdvisor to find nutrition information on calories, carbohydrates, sodium, fat and cholesterol.

“You would be surprised to see how small substitutions at meal time can make a real difference in your health,” commented Christine Tobin, CDE, President, Health Care & Education, American Diabetes Association. “MyFoodAdvisor can set you up for success by showing you healthy alternatives, tracking what you eat and helping create goals. Losing 10 or 15 pounds can help stop diabetes by preventing or delaying type 2 diabetes or diabetes complications.”

Join American Diabetes Association’s Director of Nutrition and Clinical Affairs Stephanie Dunbar, MPH, RD, and USA Today’s Medical Reporter Mary Brophy Marcus to discuss healthy eating and using the completely revised MyFoodAdvisor during a Twitter Chat on Thursday, July 15, at 2 p.m. ET, at @AmDiabetesChat and #ADA_USAT.

New features include:

  • Track It – You can create your own goals for calories, carbohydrate, sodium, saturated fat and fiber and compare what you currently are eating to what you want to be eating. This analysis allows you to make healthier options to lower sodium or saturated fat intake or to keep your carbohydrate intake consistent from day to day.
  • Spanish Version – The entire web site is now available in Spanish. The prevalence of diabetes is 2 to 4 times higher among Hispanics/Latinos.

Updated features include:

  • Healthy Alternative – This feature, unique to MyFoodAdvisor™, allows you to search for healthier foods. For example, searching for a healthier alternative to ground beef for your favorite burger recipe would provide choices for other ground meat products like turkey or even vegetable-based meat alternatives. The algorithm, based on recent research, takes into account 13 different nutrients to recommend the best alternatives based on your selections.
  • Recipe Analysis – Analyze your favorite recipes with our Create Dish functionality. You can request healthier options for all of your recipe ingredients to make your old favorite a healthier favorite. Your own recipes can be saved in your recipe box and imported into the tracking it tool, and ingredients added to a shopping list.
  • Create Dish – The portion sizes have been expanded to meet your preferences for using simple cooking measurements.
  • Simpler Navigation – The new version allows you to better search and compare food options.

“For people with diabetes and their caregivers, one of MyFoodAdvisor’s useful features remains that serving sizes are based on 15 grams of carbohydrate, which makes it easier to count carbs. There is also information on phosphorus and potassium, two important nutrients to watch for people with kidney disease,” commented Tobin. “But MyFoodAdvisor can help anyone looking to make smart food choices this summer.”

The American Diabetes Association is leading the fight to stop diabetes and its deadly consequences and fighting for those affected by diabetes. The Association funds research to prevent, cure and manage diabetes; delivers services to hundreds of communities; provides objective and credible information; and gives voice to those denied their rights because of diabetes. Founded in 1940, our mission is to prevent and cure diabetes and to improve the lives of all people affected by diabetes. For more information please call the American Diabetes Association at 1-800-DIABETES (1-800-342-2383) or visit www.diabetes.org. Information from both these sources is available in English and Spanish.

Contact:
Sarah Bradley
[email protected]
703-549-1500, ext. 2231

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Filed Under: Public Health and Research

Survey Indicates Many Healthcare Facilities Are Not Fully Applying CDC CAUTI Prevention Guidelines

Posted on July 12, 2010 Written by Editor

SOURCE: Medline Industries, Inc.

Almost Half Report Not Having an Annual Competency Validation Process for Staff on CAUTI Prevention Measure and Inserting Foley Catheters

MUNDELEIN, IL–(Marketwire – July 12, 2010) –  Only 40 percent of infection control professionals indicated that more than three-quarters of the nurses at their facility were applying the CDC’s CAUTI prevention guidelines, and less than half reported that their facilities were conducting annual education and training on alternatives to catheterization, according to a survey conducted today. The survey of infection control professionals was conducted at a breakfast forum on prevention of catheter-associated urinary tract infections (CAUTI), sponsored by Medline Industries, Inc. in conjunction with the Association for Professionals in Infection Control and Epidemiology (APIC) Annual Scientific Meeting being held in New Orleans, LA. 

Additionally, while nearly 80 percent of attendees cited CAUTI prevention as one of their facility’s top priorities this year, almost half reported that they do not have an annual competency validation process for staff to assure that they are competent in CAUTI prevention measures and inserting Foley catheters.

“These results reaffirm the need for industry vendors to partner with healthcare providers on a comprehensive system that incorporates proper procedures and social behaviors that are easy to adopt in everyday practice,” said Lorri Downs, R.N., B.S.N., M.S., C.I.C., vice president of Infection Prevention at Medline and a board certified infection preventionist. “Reducing CAUTI rates is not just about taking precautions. We must transfer knowledge to the bedside clinician in new ways such as through interactive learning and online competency validation courses to ensure industry guidelines become the standard course of care.”

That was the experience at Arkansas Methodist Medical Center, located in Paragould, AR. The organization did not have a formal education program in CAUTI prevention prior to implementing Medline’s ERASE CAUTI program, but has seen significant results since it began using the evidence-based program three months ago.

“Since we’ve been using the ERASE CAUTI program, our facility has experienced an almost 20 percent decrease in our CAUTI rate and a more than 10 percent decrease in the number of Foley catheters placed,” said Lisa Bridges, infection preventionist at Arkansas Methodist Medical Center. “I believe the decreases will be even more in the coming months. We are still in the process of educating our staff on following the guidelines. Having the checklist on the outer packaging helps us to make sure that catheterization is an appropriate option for the patient.”

Medline is highlighting evidence-based CAUTI prevention practices and products at this year’s APIC Congress (booth #1907). During the three-day exhibition, Medline is demonstrating its ERASE CAUTI program, a revolutionary new approach to managing catheters and reducing CAUTI. Based on the same criteria the CDC used in developing their new CAUTI prevention guidelines, the ground-breaking ERASE CAUTI program features a reengineered one-layered catheter tray coupled with an evidence-based clinical education program.

As part of its presentation, the Medline clinical team is conducting a series of live, multimedia overviews of its cutting edge competency validation tools for assessing and sustaining staff results. The interactive competency programs are available to staff anytime via Medline University, Medline’s online education resource, and can be easily incorporated into the annual skills competency program for a facility’s nursing staff.

CAUTI is one of the most common healthcare-associated infections, not only comprising 40 percent of all institutionally acquired infections, but also eight percent of infections in the home care setting. Studies show that one in four patients receives an indwelling urinary catheter at some point during their hospital stay and up to 50 percent of these catheters are placed unnecessarily.

Additional information on the ERASE CAUTI program is available on Medline’s website at www.medline.com/erase.

About Medline Industries, Inc. 
Medline, the nation’s largest privately held manufacturer and distributor of healthcare products, manufactures and distributes more than 100,000 products to hospitals, extended-care facilities, surgery centers, home care dealers and agencies. Headquartered in Mundelein, Ill., Medline has more than 900 dedicated sales representatives nationwide to support its broad product line and cost management services.

Over the past five years, Medline has been the fastest-growing distributor of medical and surgical supplies in the U.S., serving as the primary distributor to over 450 major hospitals and healthcare systems. As a leading distributor, Medline offers a comprehensive array of consulting and management services encompassing the supply chain and logistics, utilization and standardization, business tools and enhanced reporting capabilities and on-staff clinicians.

Media Contacts:
Jerreau Beaudoin
(847) 643-3011
John Marks
(847) 643-3309

Filed Under: Public Health and Research

CDC and APHL Partner to Enhance Public Health Labs in US and Abroad

Posted on July 12, 2010 Written by Editor

SOURCE: Association of Public Health Laboratories

SILVER SPRING, MD–(Marketwire – July 12, 2010) –  The Association of Public Health Laboratories (APHL) has received an award for $16.3 million from the Centers for Disease Control and Prevention (CDC) to enhance the work of public health laboratories in the US and abroad. The award continues an APHL-CDC collaboration of over 20 years in support of governmental health laboratories.

Funded as a five-year cooperative agreement, the award will assist APHL to promote quality public health laboratory practice, strengthen the public health laboratory system and develop a well-trained workforce. 

“APHL is committed to improving health outcomes by strengthening the capacity of public health laboratories both nationally and globally,” said Dr. Patrick Luedtke, director of the Unified State Laboratories in Utah and APHL president. “Public health laboratories protect us against diseases, environmental hazards, natural disasters and other health threats. A stronger lab system means healthier people.”

APHL is a leader in development and implementation of public health laboratory practice, systems, policy and training. Members serve as laboratory first responders, protecting the public from diseases and environmental health hazards. 

The Association of Public Health Laboratories is a national non-profit located in Silver Spring, MD, that is dedicated to working with members to strengthen governmental laboratories with a public health mandate. By promoting effective programs and public policy, APHL strives to provide public health laboratories with the resources and infrastructure needed to protect the health of US residents and to prevent and control disease globally.

Contact:
Michelle M. Forman
Senior Media Specialist
240.485.2793
Email Contact

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Filed Under: Public Health and Research

TRDX & Genesis Biopharma Announce Dr. Bahige Baroudy as Chief Science Officer to Lead Development of Potential Diabetic Neuropathy Cure

Posted on July 9, 2010 Written by Editor

SOURCE: Trend Exploration

LONG ISLAND, NY–(Marketwire – July 9, 2010) –  SciMeDent Health Corp. f/k/a Trend Exploration, Inc. (“TRDX” or the “Company”) (PINKSHEETS: TRDX) today announces plans to appoint Dr. Bahige Baroudy of Genesis Biopharma to the equivalent role of Chief Science Officer at TRDX for the continued development of a potential cure for diabetic neuropathy.

Dr. Bahige Baroudy has multi-disciplinary expertise in basic research, infectious disease drug discovery and virology. Prior to joining Genesis Biopharma, Dr. Baroudy was a Group Director at Schering-Plough where he spearheaded the development of CCR5 antagonists that are currently in clinical trials as HIV entry inhibitors and earned a place on “The Scientific American 50” list as the top Research Leader in 2003 in this category. He was also the Director, Division of Molecular Virology at the James N. Gamble Institute of Medical Research, where he established research programs in viral hepatitis and liver diseases, HIV/AIDS and vaccinia virus expression and pathogenesis. Dr. Baroudy has also worked at the NIH in several disciplines.

Dr. Baroudy stated: “We are pleased that we have received the approval of Health Canada to proceed to Phase 1 clinical studies.”

Dr. Jan Stahl, CEO of TRDX, commented: “We look forward to the work Dr. Baroudy will execute in bringing this potential cure to market.”

About Genesis Biopharma, Inc.
Genesis Biopharma, Inc. (www.genesisbiopharma.com) is a Canadian corporation founded in 2007 to exploit the commercial potential for the therapeutic use of peptidomimetic (modified amino acid peptides) compounds. Amino acids are the building blocks of proteins, which are found in every cell of every living thing on Earth. Proteins consist of extremely long and complex amino acid chains. In contrast, a peptide is a short string of amino acids, joined by chemical bonds (also called “amide bonds”).

About SCIMEDENT f/k/a Trend Exploration, Inc. (PINKSHEETS: TRDX)

SciMeDent (www.scimedenthealth.com) is a company focused on being a leading developer and marketer of products and services for medicine, dentistry and life sciences. SciMeDent plans to achieve growth initially through mergers and acquisitions.

Cautionary Statement Regarding Forward-Looking Statements
A number of statements contained in this press release are forward-looking statements. These forward-looking statements involve a number of risks and uncertainties, including the sufficiency of existing capital resources, technological or industry changes and uncertainties related to the development of the Company’s business model. The actual results the Company may achieve could differ materially from any forward-looking statements due to such risks and uncertainties.

Filed Under: Public Health and Research

DiaMedica Initiates Type 1 Diabetes Study; Announces Preliminary Results

Posted on July 8, 2010 Written by Editor

WINNIPEG, MANITOBA–(Marketwire – July 8, 2010) – DiaMedica Inc., (TSX VENTURE:DMA) today announces that it has initiated a Type 1 diabetes program. The recently announced Sanomune acquisition allows DiaMedica to expand into Type 1 diabetes. The initiation of this program is based on encouraging preclinical results with DM-99, a naturally occurring protein that the company has previously shown to have clinical efficacy for Type 2 diabetes.

In the study, animals were injected with streptozotocin, a naturally occurring compound known to be toxic to beta cells, to mimic the disease. A week after this streptozotocin treatment, animals were injected twice daily with DM-99 for a period of 21 days at which time fasting blood glucose measurements were taken. Animals treated with DM-99 had a statistically significant 68% (p=0.05) reduction in fasting blood glucose compared to untreated animals. Furthermore, the DM-99 treatment resulted in a positive reduction in total glucose as measured by an oral glucose tolerance test.

“Initial results from this study show that DM-99 was able to reduce fasting blood glucose, an indication that new beta cells may be created or that existing beta cells are being protected from the streptozotocin insult,” stated Rick Pauls, President and CEO of DiaMedica. “The final results and analysis of DM-99 on the direct effects upon the pancreas (insulin production and beta cell proliferation) is expected during the summer of 2010.”

About Type 1 Diabetes

According to the Juvenile Diabetes Research Foundation, as many as 3 million Americans may have Type 1diabetes, an autoimmune disease that strikes children and adults suddenly and can be fatal. In Type 1 diabetes, the host’s own immune system destroys beta cells in the pancreas that normally control blood sugar level by producing insulin. Currently, patients with Type 1 diabetes have to test their blood sugar and give themselves insulin injections multiple times each day, or use a pump daily to control blood sugar levels. Even with intensive care, insulin is not a cure for diabetes, nor does it completely prevent the eventual and devastating complications of diabetes, which may include kidney failure, blindness, heart disease, stroke, and amputation.

About DiaMedica

DiaMedica is a biopharmaceutical company focused on developing novel treatments for diabetes and neurological disorders. The Company’s Type 2 diabetes program is based on a critical liver nerve signaling mechanism involved in enhancing insulin sensitivity after meal consumption. Two of DiaMedica’s products have previously demonstrated human efficacy in lowering blood sugar levels in people diagnosed with Type 2 diabetes based on this novel nerve signaling mechanism.

DiaMedica has expanded its DM-199 recombinant protein program into neurological and autoimmune disorders. The Company has demonstrated that DM-99, the naturally occurring form of DM-199, confers neural protection (protects brain cells) and triggers neural stem cell proliferation (creates brain cells) for the treatment of numerous neurological disorders including Alzheimer’s disease. DiaMedica is listed on the TSX Venture Exchange under the trading symbol “DMA”.

For further information please visit www.diamedica.com.

Caution Regarding Forward-Looking Information

Certain statements contained in this press release constitute forward-looking information within the meaning of applicable Canadian provincial securities legislation (collectively, the “forward-looking statements“). These forward-looking statements relate to, among other things, DiaMedica’s objectives, goals, targets, strategies, intentions, plans, beliefs, estimates and outlook, and can, in some cases, be identified by the use of words such as “believe,” “anticipate,” “expect,” “intend,” “plan,” “will,” “may” and other similar expressions. In addition, any statements that refer to expectations, projections or other characterizations of future events or circumstances are forward-looking statements. Specifically, this press release contains forward-looking statements regarding matters such as, but not limited to, the anticipated use of proceeds from the Offering, management’s assessment of DiaMedica’s future plans, information with respect to the advancement of DiaMedica’s research and development programs, and DiaMedica’s other estimates and expectations. These statements reflect management’s current beliefs and are based on information currently available to management. Certain material factors or assumptions are applied in making forward-looking statements, and actual results may differ materially from those expressed or implied in such statements. Important factors that could cause actual results to differ materially from these expectations include, among other things: uncertainties and risks related to our research and development programs, the availability of additional financing, risks and uncertainties relating to the anticipated use of proceeds, changes in debt and equity markets, uncertainties related to clinical trials and product development, rapid technological change, uncertainties related to forecasts, competition, potential product liability, additional financing requirements and access to capital, unproven markets, the cost and supply of raw materials, management of growth, effects of insurers’ willingness to pay for products, risks related to regulatory matters and risks related to intellectual property matters. Additional information about these factors and about the material factors or assumptions underlying such forward-looking statements may be found in the body of this news release, as well as under the heading “Risk Factors” contained in DiaMedica’s 2009 annual information form. DiaMedica cautions that the foregoing list of important factors that may affect future results is not exhaustive. When relying on DiaMedica’s forward-looking statements to make decisions with respect to DiaMedica, investors and others should carefully consider the foregoing factors and other uncertainties and potential events. Such forward-looking statements are based on a number of estimates and assumptions, which may prove to be incorrect, including, but not limited to, assumptions regarding the availability of additional financing for research and development companies, and general business and economic conditions.These risks and uncertainties should be considered carefully and investors and others should not place undue reliance on the forward-looking statements. Although the forward-looking statements contained in this press release are based upon what management believes to be reasonable assumptions, DiaMedica cannot provide assurance that actual results will be consistent with these forward-looking statements. DiaMedica undertakes no obligation to update or revise any forward-looking statement. Additional risk factors, factors which could cause actual results to differ materially from expectations, and assumptions relating specifically to our acquisition of Sanomune may be found in our press releases dated February 18, 2010 and April 20, 2010.

Filed Under: Prescription Drugs and Pharmacy, Public Health and Research

www.RoboticOncology.com: Dr. David Samadi, MD Finds That Obesity Does Not Impact Outcomes From Robotic Prostate Surgery

Posted on July 7, 2010 Written by Editor

SOURCE: RoboticOncology.com

NEW YORK, NY–(Marketwire – July 7, 2010) –  At the recent 25th Annual European Association of Urology Congress, Dr. David Samadi, Chief of the Division of Robotics and Minimally Invasive Surgery at The Mount Sinai Medical Center in New York City, presented findings that showed that obesity does not adversely impact the outcomes of robotic-assisted laparoscopic prostatectomies (RALP) for prostate cancer treatment. These findings contradict the popular opinion that non-obese patients fare better than their obese counterparts after having robotic surgery for prostate cancer.

Dr. Samadi presented findings from a study that followed 1,112 men who underwent RALP for prostate cancer treatment. The results were that the perioperative, pathologic, and functional outcomes were the same regardless if the patients were obese or not. “Previously it had been thought that obese patients do not do well after RALP because of the way their high BMI affects their outcomes, but there wasn’t enough data to support that notion,” said Dr. Samadi. Ironically, previous data has shown that obese patients have worse outcomes with traditional open prostatectomy versus a robotic prostatectomy.

In fact, the new study showed that both obese and non-obese subjects had similar Gleason scores (a grading system used to predict the behavior of prostate cancer), positive margins, biochemical recurrence, and surgical complications. They had comparable operating times and approximate blood loss. Their post-operative continence rates were similar at three, six, and 12 months. Their post-operative sexual function rates were also very similar at the same stages. “While there is an increased incidence of prostate cancer in men with high BMI, the bottom line is that RALP is effective and safe for these types of patients,” Dr. Samadi said.

“The only barrier to operating on an obese patient would be the surgical challenges that arise as a result of their body mass,” explained Dr. Samadi. A typical RALP takes Dr. Samadi about 90 minutes to perform. With obese patients, surgeries can often go beyond three hours, and if the surgeon does not have the required experience with these kinds of cases, many complications such as DVT, blood clots in lower extremities or overall edema can arise. “I always recommend that a very experienced, high-volume surgeon perform the procedure,” advised Samadi.

Contact:

Dr. David B. Samadi
1-888-762-6810
www.RoboticOncology.com

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Filed Under: Hospitals and Health Systems, Public Health and Research

Cystinosis Research Foundation Awards $988,759 in Grants to Find a Cure for Deadly, Genetic Disease

Posted on July 6, 2010 Written by Editor

SOURCE: Cystinosis Research Foundation

IRVINE, CA–(Marketwire – July 6, 2010) –  The Cystinosis Research Foundation of Irvine, Calif., announced it has awarded $988,759 in grants to seven specialized research studies in the United States, France, Belgium and Ireland that are focused on finding a cure for cystinosis and improving understanding of the rare, deadly metabolic and genetic disease. Cystinosis afflicts about 500 children and young adults in the U.S. and 2,000 worldwide.

“The $11.8 million in cystinosis research grants awarded to date has resulted in an important milestone. The CRF’s mission to find a better treatment for cystinosis has been realized with the final Phase 3 clinical trial of Delayed-Release Cysteamine currently under way at Emory University and soon to be at several other sites in the U.S. and Europe. Without the concerted effort of CRF, we would not be where we are today. We are very close to unlocking the mysteries of this terrible disease,” said Nancy Stack, CRF Trustee and President.

The CRF is the leading funding source for bench and clinical investigations of cystinosis worldwide.

The foundation’s latest round of funding follows the recent formation of the CRF Cystinosis Gene Therapy Consortium. The consortium’s goal is to advance progress on the most promising current findings, including moving novel therapeutic modalities into human patients as quickly as possible. Work is now under way at The Scripps Research Institute in La Jolla, Calif., to develop the necessary preclinical animal model data and translate these results into an FDA-approved clinical trial.

The CRF is launching the Cure Cystinosis International Registry (CCIR), whose purpose is to consolidate information about cystinosis patients into a single data repository which will help advance research and clinical trials leading to future treatments and cures.

The CRF awards research grants in the spring and fall of each year. The latest round of funding awards were presented to researchers at the University of California campuses at Irvine and San Diego; Massachusetts General Hospital; State University of New York at Buffalo; University Hospital, Leuven, Belgium; University College, Cork, Ireland; and a team from the Institut de Biologie Physico-Chimique, Paris; and the University Medical Center, Mainz, Germany.

Cystinosis is a metabolic disease that slowly destroys every organ in the body, including the liver, kidneys, eyes, muscles, thyroid and brain. There is a medicine that prolongs the children’s lives, but there is no cure. Most cystinosis sufferers succumb to the disease or its complications by age 40.

In patients with cystinosis, the amino acid cystine accumulates in the tissue due to the inability of the body to transport cystine out of the cell. This causes development of crystals, resulting in early cell death.

“The advancements achieved thus far are the result of CRF’s focused efforts and targeted approaches to research. We are dedicated to bringing the first stem cell and gene therapy clinical trial for cystinosis to reality. We hope that, if all goes well, there will be a clinical trial for a cure within the next two to three years,” she said. The CRF currently is funding 48 research studies, including 13 research fellows worldwide.

Nancy Stack and her husband, Geoffrey, a managing director of the SARES•REGIS Group, an Irvine real estate company, have a daughter, Natalie, 19, with cystinosis.

Every dollar raised by the CRF is committed for medical research. Administrative costs are privately underwritten. All grants are awarded based on evaluations by the CRF’s Scientific Review Board, which is comprised of leading doctors and research scientists in the field.

SPRING 2010 RESEARCH GRANTS FUNDED

Total: $988,759

Alan Davidson, PhD, Principal Investigator
Massachusetts General Hospital, Boston, Massachusetts
“Characterization and Rescue of CTNS-iPS Cells”
$129,557 – 1 year grant

Bruno Gasnier, PhD, Principal Investigator
Institut de Biologie Physico-Chimique, Paris, France
Ellen Closs, PhD, Co-Investigator
University Medical Center, Mainz, Germany
“Molecular Study of Lysosomal Transporters Involved in the Cystine-depleting Effect of Cysteamine”
$169,384 – 2 year grant

Patrick Harrison, PhD, Mentor and Ciaran Lee, Research Fellow
University College, Cork, Ireland
“Cystinosis Gene Repair”
$146,258 – 2 year grant

Elena Levtchenko, MD, PhD, Mentor and Joost Schoeber, PhD, Research Fellow
University Hospital, Leuven, Belgium
“Studying Podocyte Function in Nephropathic Cystinosis”
$150,000 – 2 year grant

Miriam Britt Sach, MD, PhD, Principal Investigator
University of California, San Diego
“In Vivo ATP Metabolism in Cystinosis Patients as Assessed by MR Spectroscopy”
$109,493 – 1 year grant

Jennifer Simpson, MD, Principal Investigator
James Jester, PhD, Co-Investigator
University of California, Irvine
“Novel Treatment Modalities for Corneal Cystinosis”
$180,000 – 2 year grant

Mary Taub, PhD, Principal Investigator
State University of New York at Buffalo
“Mechanisms Underlying the Fanconi Syndrome in Cystinosis”
$104,067 – 1 year grant

The Cystinosis Research Foundation is the largest non-profit provider of funds for cystinosis research in the world. For more information, call Zoe Solsby at (949) 223-7610 or visit www.cystinosisresearch.org.

Zoe Solsby
(949) 223-7610

Art Barrett
(714) 602-6021

Filed Under: Healthcare Business, Public Health and Research

EmpowHER Offers Free Resources and Information for Women With Questions About Umbilical Cord Blood

Posted on July 6, 2010 Written by Editor

SOURCE: EmpowHER

EmpowHER Provides Special Resource Page in Support of Cord Blood Awareness Month

SCOTTSDALE, AZ–(Marketwire – July 6, 2010) –  EmpowHER is offering free access to world-class health information as well as a community of experts and advocates to the millions of women interested in current research on cord blood and stem cells. These resources are offered in support of the Cord Blood Awareness Month, which occurs in July and is sponsored by the American Hospital Association.

Cord blood is the blood located inside the umbilical cord after the cord has been cut. It is rich with stem cells, which have the ability to regenerate and form cells that create all other tissues, organs, and systems in the human body. The unique and special characteristics of cord blood cells provide the possibility of healing some cancers or inherited diseases. Also, according to the American Pregnancy Association, cord blood stem cells are oftentimes rejected less by the body as compared to healthy adult bone marrow stem cells. If a parent elects to do so, cord blood can be stored at the time of an infant’s delivery for medical use in the future. Some experts question the effectiveness of storing cord blood, however, as it may contain the same cells that caused a disease or medical condition in the child, the National Institutes of Health reports.

According to research published in the Journal of Reproductive Medicine, 3 out of every 4 pregnant women consider themselves only “minimally informed” about this issue.

For women wanting to learn more about this issue, EmpowHER offers invaluable content on its site where women can find topical medical articles and guides to additional online resources on cord blood and stem cell research and therapies.

To access cord blood content on EmpowHER, please click the links below:
Cord Blood Resource Page
Thinking About Cord Blood Banking?
Cord Blood Donation
Cord Blood Banking – The Medicine of the Future?
Growing New Organs From Cord Blood – Why Transplants May Not Be Needed In Future
Can Obama Cure Cancer With Stem Cell Research?

“More women need to understand what cord blood donation really entails and what the reasons behind it are,” says Michelle King Robson, EmpowHER’s Founder, Chairperson and CEO. “This way, pregnant women considering cord blood donation can make more informed decisions when offered this option at childbirth.”

About EmpowHER
EmpowHER is an award-winning health media company for women. The Company’s website provides visitors access to one of the largest women’s health and wellness content libraries on the web, as well as the largest online community of women discussing their health and wellness issues. EmpowHER promotes a “24 Hour Promise” to its visitors, who can come to the site, ask any health question and receive a response within 24 hours. Health care marketers rely on EmpowHER for reaching the most influential health and wellness buying audience on the Internet — women. Millions of women visit EmpowHER.com every year, making it one of the largest and fastest-growing resources dedicated exclusively to women’s health and wellness. For more, visit www.empowher.com.

Press Contacts
Joanna LeBlang
EmpowHER
(480) 315-1443
Email Contact

Jay Geer
Miller Geer Arizmendez
(562) 467-2020
Email Contact

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Filed Under: Public Health and Research

HHS Secretary Sebelius Joins Leaders From the National Institutes of Health, Food & Drug Administration and Academia to Discuss New Roles in Drug…

Posted on July 6, 2010 Written by Editor

SOURCE: Ewing Marion Kauffman Foundation

KANSAS CITY, MO–(Marketwire – July 6, 2010) –  Academic institutions across the United States are playing a critical role in developing life-saving treatments, procedures and innovations, and must be supported by a public policy agenda designed to foster continued growth and investment, U.S. Secretary of Health and Human Services Kathleen Sebelius told a gathering of leaders from the public and private sectors here today. Friends of Cancer Research, Kansas Bioscience Authority, The University of Kansas Cancer Center, Ewing Marion Kauffman Foundation, and Council for American Medical Innovation convened today’s symposium titled The New Role of Academia in Drug Discovery and Development: New Thinking, New Competencies, New Results.

The program also included a moderated discussion with Dr. Francis Collins, director of the National Institutes of Health (NIH), and Dr. Margaret Hamburg, commissioner of the Food and Drug Administration (FDA) on agency perspectives to fostering innovation and increased collaboration. The discussion was moderated by former U.S. House Majority Leader and Chairman of the Council for American Medical Innovation, Richard Gephardt.

“This is a rare opportunity for anyone involved in cancer research and drug development,” said Roy A. Jensen, M.D., director of The University of Kansas Cancer Center. “To have so many key policy makers, academics, industry-leaders, and the non-profit community represented, discussing ways to drive new collaborations is extraordinary. As universities’ appetites for commercializing research grow and high-throughput platforms are increasingly adopted in public research programs, we seem to be seeing a new paradigm for drug discovery. We feel The University of Kansas Cancer Center is leading this effort in the new innovation ecosystem.” 

The day-long town hall, a result of collaboration between several like-minded organizations, explored drug development from the perspectives of thought-leaders from academia, government, industry and the nonprofit sector.

“This town hall, and the participation by scientific leadership at the highest levels, is an important step toward much-needed increased interagency collaboration,” said Dr. Ellen Sigal, chair, Friends of Cancer Research. “The proposals discussed today will accelerate the process to help get scientific breakthroughs to patients. Without collaboration among all agencies and academic centers, the full potential of biomedical research may be stifled.” 

“Discoveries from our academic labs fuel millions of jobs, spur small business, and promote innovation. The time is right for a fundamental re-examination of the changing role of academic institutions in the innovation process,” said Tom Thornton, president and chief executive officer, Kansas Bioscience Authority.

About Friends of Cancer Research

Friends of Cancer Research (Friends) is a cancer research think tank based in the Washington, D.C. area. Working with the entire cancer research and advocacy community, Friends pioneers innovative public-private partnerships, organizes critical policy forums, educates the public, and brings together key stakeholders to overcome the barriers standing between patients and the most promising cancer treatments.

About The University of Kansas Cancer Center

At The University of Kansas Cancer Center, we are more than an academic cancer center; we are a unique community-based cancer research and care partnership focused on one mission: eliminating the burden of cancer. The University of Kansas Cancer Center is transforming cancer research and clinical care by linking our innovative approach to drug discovery, delivery and development to our nationally accredited patient care program.

About the Ewing Marion Kauffman Foundation

The Ewing Marion Kauffman Foundation is a private nonpartisan foundation that works to harness the power of entrepreneurship and innovation to grow economies and improve human welfare.

About the Council for American Medical Innovation

The United States faces serious challenges to maintaining its leadership position in innovation. The Council for American Medical Innovation is bringing together leaders in research, medicine, public health, academia, education, labor, investment and business, who are working in partnership toward a national policy agenda aimed at preserving U.S. leadership in medical innovation. American medical innovators create millions of high-paying jobs, and their discoveries are integral in the fight to cure cancer and other illnesses. The Council for American Medical Innovation views leadership in medical innovation as a key part of America’s economic recovery, future prosperity and health.

About the Kansas Bioscience Authority

The KBA is a $581 million initiative that is advancing Kansas’ national bioscience leadership by building world-class research capacity; fostering the formation and growth of bioscience startups; supporting expansion of the state’s bioscience clusters; and facilitating industrial expansion and attraction.

Contact:
Ryan Hohman
(717) 333-6248
[email protected]

Barbara Pruitt
(816) 932-1288
[email protected]

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Filed Under: Healthcare Policy and Law, Public Health and Research

A Quick Overview on the Hospitals Industry

Posted on July 2, 2010 Written by Editor

SOURCE: Rothman Research

JOHANNESBURG, SOUTH AFRICA–(Marketwire – July 2, 2010) –  www.rothmanresearch.com — Healthcare spending in the U.S. accounts for close to 16% of the nation’s GDP and according to estimate of every dollar disbursed on health care 31% is allocated to hospital care. There are over 6000 hospitals, government or privately administered, scattered throughout the U.S. territories, employing over 4.5 million workers and generating an overall yearly revenue of about $700 billion. Accounting for almost 2% of the market, Community Health Systems Inc. (NYSE: CYH) is regarded as the biggest for-profit general healthcare services in the country.

*Free downloadable research reports on Health Management Associates Inc. and Community Health Systems Inc. are available by signing up now at http://www.rothmanresearch.com/article/hma/23652/Jul-02-2010.html or http://www.rothmanresearch.com/article/cyh/23653/Jul-02-2010.html

A major milestone in the industry which also impacted the whole of the healthcare sector was achieved in March 2010 when the healthcare reforms were passed as law. With this new law additional patients in their millions (between 31 to 32 millions) will now be covered by health insurance. The Patient Protection and Affordable Care Act also encourage healthcare institutions to start the creation of a universal database of electronic medical records. Mercy Health Systems is amongst those which have already started experimenting with this new system. 

www.rothmanresearch.com is a source for investors seeking free information on Hospitals industry; investors are encouraged to sign up for free at http://www.rothmanresearch.com/index.php?id=6&name=Register.

Hospitals in the U.S. are very close to the monopoly concept, and one of the key reasons why hospital operators like Health Management Associates Inc. (NYSE: HMA) can achieve this kind of regional dominion is through consolidation. Recently, Health Management Associates has announced the acquisition of 60% controlling shares in three Shands Healthcare hospitals.

Companies looking for additional media or advertising services can call Blue Chip IR at 1-917-267-8836

About Rothman Research
Rothman Research brings independent company and sector research together, utilizing top financial advisors and investment tactics to provide you with a clear picture of investment opportunities.

For More Information Contact:
Jack Benassi
[email protected]

Filed Under: Hospitals and Health Systems, Public Health and Research

First Study Ever on Effect of Wood Smoke in Smokers Conducted by the Lovelace Respiratory Research Institute

Posted on July 1, 2010 Written by Editor

SOURCE: Lovelace Respiratory Research Institute

First Study on Wood Smoke Effects on COPD in US

ALBUQUERQUE, NM–(Marketwire – July 1, 2010) –  The nation’s first scientific study on the effects of wood smoke in smokers shows that wood smoke is associated with chronic obstructive pulmonary disease (COPD), and has identified a link that increases the risk for reduced lung function in cigarette smokers. That exposure to wood smoke causes COPD was previously found to be common in women in developing countries, but has not been recognized as being a hazard at concentrations generally found in developed countries. 

The objective was to evaluate the risk of wood smoke for COPD in a population of smokers in the United States, and whether non-hereditary changes of DNA that were detected in sputum samples of these patients were correlated to the disease of COPD as shown by the destruction of lung function. The association between wood smoke and reduced lung function was stronger among current cigarette smokers, non-Hispanic whites and men.

Lead investigators at Lovelace Respiratory Research Institute (LRRI) in New Mexico, the only dedicated respiratory research center in the US, in collaboration with the University of New Mexico School of Medicine and the University of Colorado at Denver, conducted the study which was financed by the appropriation from the Tobacco Settlement Fund, and from the National Institutes of Health (NIH). The findings were recently published in the American Journal of Respiratory Critical Care Medicine, a publication by the American Thoracic Society.

Yohannes Tesfaigzi, Ph.D., Senior Scientist at LRRI based in ABQ, NM and lead investigator, said, “The findings are significant and timely because it shows that there are many factors that reduce lung function in the world today.” Tesfaigzi continued, “Our findings suggest that smokers of cigarettes who are exposed to wood smoke increase their risk of having reduced lung function.”

For the research, a cross sectional study of 1,827 subjects were drawn from the Lovelace Smokers’ Cohort, a predominantly female cohort of smokers that is unique with its high percentage of Mexican Hispanic participants. The wood smoke exposure was self-reported. The research included measuring air entering and leaving the lungs, airflow obstruction and chronic bronchitis. Also explored were modification of wood smoke exposure with current cigarette smokers, ethnicity, sex, and the relationship with lung cancer-related genes on COPD. 

Robert W. Rubin, Ph.D., CEO of Lovelace Respiratory Research Institute, said, “Many people use wood smoke as a major heating source and also smoke cigarettes, and this research proves that it can be a very unhealthy combination.” Rubin continued, “With the legitimate concern to find alternative energy and heating methods in the world, we need more research of this kind to make certain that we do not add to the many factors in the air we breathe that will contribute to the destruction of lung function.” 

About Lovelace Respiratory Research Institute

The Lovelace Respiratory Research Institute (LRRI) is a private, biomedical research organization dedicated to improving public health through research on the prevention, treatment and cure of respiratory disease. LRRI is committed to curing respiratory diseases through research aimed at understanding their causes and biological mechanisms; assessing and eliminating exposures to respiratory health hazards; and developing improved therapeutics, vaccines, and diagnostics. LRRI is based in Albuquerque, New Mexico, employs 1100 people, and is a $125 million company. www.lrri.org

Contact:
Kyla Thompson
[email protected]
505-366-7222

Click here to see all recent news from this company

Filed Under: Public Health and Research

American Diabetes Association Statement on Blood Glucose Lowering Drugs

Posted on June 30, 2010 Written by Editor

SOURCE: American Diabetes Association

ALEXANDRIA, VA–(Marketwire – June 30, 2010) –  The American Diabetes Association does not have official position favoring or recommending against specific drugs that are approved by the FDA to lower glucose. The 2009 consensus statement on medical management of hyperglycemia in type 2 diabetes does not reflect official position of the ADA but rather the expert opinion of the authors of the paper.

Recently, additional information regarding the cardiovascular safety of rosiglitazone was reported, with some analyses suggesting a possible increase in risk and others supporting the drug’s safety. This information as well as past reports of a potential increase in the risk of CVD is being reviewed by the FDA. The Association’s staff and volunteer leadership are also reviewing the information in the public domain and await further information from the FDA. Until further information is provided, patients and health care professionals should continue to recognize that multiple classes of drugs, often with more than one agent per class, are available to maintain glucose control in type 2 diabetes.

The decision whether or not to use any medication must remain that of the treating physician in direct discussion with their patients. As additional information becomes available, the Association will provide detailed updates for both health care professionals and patients with diabetes. Patients should continue taking all currently prescribed medications unless otherwise informed by their health care team.

The American Diabetes Association is leading the fight against the deadly consequences of diabetes and fighting for those affected by diabetes. The Association funds research to prevent, cure and manage diabetes; delivers services to hundreds of communities; provides objective and credible information; and gives voice to those denied their rights because of diabetes. Founded in 1940, our mission is to prevent and cure diabetes and to improve the lives of all people affected by diabetes. For more information, please call the American Diabetes Association at 1-800-DIABETES (1-800-342-2383) or visit www.diabetes.org. Information from both these sources is available in English and Spanish.

Contact:
Colleen Fogarty
703-549-1500, ext. 2146

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Filed Under: Prescription Drugs and Pharmacy, Public Health and Research

Mixed Results From ACCORD: Study Found No Overall Reduction in Cardiovascular Risk, but Benefits to Eyes, Kidneys and Nerves

Posted on June 29, 2010 Written by Editor

SOURCE: American Diabetes Association

Potential Benefits of Intensive Blood Glucose Lowering Must Be Weighed Against Higher Mortality Risk

ORLANDO, FL–(Marketwire – June 29, 2010) –  Five-year results of the Action to Control Cardiovascular Risk in Diabetes (ACCORD) study confirm that neither more intensive lowering of blood glucose (sugar) levels, more intensive lowering of blood pressure, nor treatment of blood lipids with a fibrate and a statin drug reduce cardiovascular risk in people with established type 2 diabetes who are at severely high risk for cardiovascular events. However, the study did find improvements to microvascular conditions, such as progression of diabetic eye disease (retinopathy), visual acuity, and renal and nerve function. The landmark study is sponsored by the federal government through the National Institutes of Health (NIH).

Speaking at the American Diabetes Association’s 70th Scientific Sessions®, the ACCORD Study Group cautioned that any potential benefits must be weighed against the increased risk of mortality and episodes of seriously low blood glucose that were seen to accompany intensive lowering of blood glucose levels — which in ACCORD was focused on achieving normal A1C levels in the study population. They emphasized that both the positive and negative results of the study apply only to this population of middle-aged or older people with type 2 diabetes for an average of 10 years, who also had a history of cardiovascular disease (CVD) or at least two risk factors for CVD.

“These results underscore the importance of patient-centered care that stresses individual treatment choices made in consultation with a physician,” said Denise Simons-Morton, MD, Ph.D, Director of the Division for the Application of Research Discoveries at the NIH’s National Heart, Lung and Blood Institute (NHLBI), the primary sponsor of the study. “Within this group, it’s important for patients and doctors to decide the highest priority for the patient,” she said. “Is improved eye health worth a higher risk of death and low blood sugar episodes? That’s a question only a fully informed patient can answer.”

The ACCORD researchers set out to investigate whether cardiovascular risk in people with type 2 diabetes could be reduced using one of the following strategies, each compared with standard treatment: intensive lowering of blood glucose to near-normal levels (target A1C less than 6%), intensive lowering of blood pressure to near-normal levels, or treatment of blood lipids with a combination of fibrate and statin drugs. It also looked at how each of these treatments would affect other outcomes such as mortality and microvascular outcomes (e.g., eye, kidney and nerve complications). 

NHLBI prematurely halted the intensive blood-glucose lowering strategy after 3.5 years, in February 2008, due to safety concerns caused by an unexpected higher incidence of death in the intensive glucose lowering treatment group compared with the standard treatment group. Patients in the intensive treatment arm of the study were transitioned into the standard treatment arm for the remainder of the trial’s five years, which has now concluded.

Intensively Lowering Blood Glucose: Increased Mortality and No Cardio Benefit, But Possible Benefits to Eyes, Kidneys and Nerves

Results of intensive glucose lowering on microvascular outcomes were published today in the Lancet and presented at a symposium at the American Diabetes Association’s 70th Scientific Sessions in Orlando.

The study examined patients who underwent intensive glucose-lowering treatment for 3.5 years (increased medication aimed at lowering A1C levels to less than 6 percent) and were then given standard treatments (aimed at achieving A1C levels of 7.0-7.9%) for the remaining 1.5 years, compared with standard treatment for the duration of the study. The intensively treated patients did not see a reduced incidence of cardiovascular disease.

In addition, the groups did not differ in overall measures of microvascular health, for example, in the progression rates to kidney failure, major vision loss, or advanced peripheral neuropathy, a common nerve problem in diabetes that usually begins as tingling or numbness in the feet. However, there were some microvascular improvements noted, such as a reduced incidence of albuminuria (protein in the urine, a marker of kidney disease) in the intensive group, compared to those receiving standard treatment, along with fewer cataract extractions during the study period. Visual acuity (sharpness of vision) and nerve function scores were also better for the intensive group than for the standard-treatment group, suggesting that intensive lowering of blood glucose may also help prevent eye and nerve damage.

“Patients who develop macroalbuminuria are prone to renal failure and cardiovascular events,” said Faramarz Ismail-Beigi, MD, Ph.D, of Case Western Reserve University and the lead researcher on this portion of the study. “Less protein in the urine is a very good sign.”

Though the visual acuity tests were somewhat subjective, Ismail-Beigi said, they could indicate that intensive glucose lowering helps to prevent eye damage.

Intensively Lowering Blood Glucose, Treating Lipids: Slows Retinopathy Progression

That finding is further supported by a substudy of ACCORD chaired by Emily Chew, MD, chief of the Clinical Trials Branch of the Division of Epidemiology and Clinical Applications at the NIH’s National Eye Institute (NEI). Results of the study were published online in the New England Journal of Medicine today. Chew and her colleagues investigated whether each treatment arm of the ACCORD trial — blood glucose, blood pressure, and blood lipids — would reduce the progression of diabetic eye disease (or retinopathy) in a subset of about 3,000 ACCORD study participants, compared to that treatment’s standard approach. Disease progression was identified through retinal photographs that indicated blood vessel changes or by the need for laser or vitrectomy surgery to treat abnormal blood vessels.

The study found that people in the intensive blood glucose lowering arm, as well as those who received a combination of a fibrate and a statin for blood lipids, experienced slower progression in diabetic retinopathy than those in each standard treatment arm. Those who were in the intensive blood pressure lowering arm did not see a reduction in eye disease progression when compared to people receiving standard blood pressure control.

Compared with standard blood glucose control, intensive control decreased the progression of diabetic retinopathy by about one-third, from 10.4 percent to 7.3 percent, over four years. Participants in the intensive control group had a median blood glucose level of 6.4 percent hemoglobin A1C — a level close to values in people without diabetes. The standard blood glucose control group maintained a median level of 7.5 percent.

In addition, compared with simvastatin treatment alone, combination lipid therapy with fenofibrate plus simvastatin also reduced disease progression by about one-third, from 10.2 percent to 6.5 percent, over four years. No prior clinical trial has shown that the combination of fenofibrate and simvastatin reduces diabetic eye disease progression.

Contrary to predictions, there was no difference in diabetic retinopathy progression among participants treated to an intensive systolic blood pressure (the top number in a blood pressure reading) target of less than 120 mm Hg, compared with those treated to a standard target of less than 140 mm Hg.

“The results of the ACCORD Eye Study indicate that intensive blood sugar control and combination fibrate plus statin treatment of lipids independently reduce diabetic retinopathy progression,” Chew said. “However, patients and their doctors should work together to develop an individual treatment plan, taking into account the potential risks of intensive glucose treatment.”

Combination Lipid Treatment: No Cardio Benefits Overall, But Subgroup May See Reduced Risk

Combination lipid therapy with a statin plus a fibrate did not help lower cardiovascular risks overall, but the results did suggest that a subgroup of the study — those with high triglycerides and low HDL (the so-called “good” cholesterol) — may benefit by such treatment.

In this subpopulation of the investigation, which included about 15 percent of the 5,518 people studied in the ACCORD Lipid Trial, those who had triglyceride levels of more than 200 and HDL levels below 34 saw a reduced incidence of cardiovascular events of 30 percent. These findings are supported by similar findings of subgroup populations in several large previously published clinical studies.

“If it were an isolated finding in our study I’d be less enthusiastic,” said Henry Ginsberg, MD, Irving Professor of Medicine and Director of the Irving Institute for Clinical and Translational Research at Columbia University. “But this finding is in line with subgroup analyses in several other trials.”

A second subgroup analysis of this arm of the study found that women and men respond differently to combination lipid therapy, Ginsberg said. Though overall the study found no cardiovascular benefits for the study population, when broken down by gender, the results showed men experienced a 20 percent reduction in cardiovascular events, while women experienced a 38 percent increase in cardiovascular events.

However, when examined for statistical significance, “the data for men showed a strong indication that they benefitted, while the data for women were not as conclusive,” Ginsberg said. “This raises possibilities that need to be further examined.”

These results were published in the April 29, 2010, issue of the New England Journal of Medicine.

Intensively Lowering Blood Pressure: No Cardio Benefits, But Suggested Reduction in Stroke

Results from the intensive blood pressure control arm of the study were also published in April in the New England Journal of Medicine. In this treatment arm, participants lowered blood pressure levels to “normal” levels of less than 120 mm Hg, to see if doing so would reduce major cardiovascular events, compared with standard treatment of levels less than 140 mm Hg. No significant reduction in overall CVD events was found.

The study did find a significant (41 percent) reduction in stroke, which was consistent with other BP-lowering clinical trials. However, because this was not the primary focus of the study, and because the overall rate of stroke was low, the researchers are hesitant to recommend a strategy of lowering blood pressure to this degree without further study.

“Older patients with known cardiovascular disease, higher blood pressure to begin with, and African Americans may benefit from such a treatment plan,” said William Cushman, MD, of the Memphis Veterans Affairs Medical Center, “but we’re going to have to do further analyses.”

The NHLBI is the primary sponsor of ACCORD, with additional funding and scientific expertise contributed by the National Institute of Diabetes and Digestive and Kidney Diseases. Other components of the NIH — including the National Institute of Aging — as well as the Centers for Disease Control and Prevention, support substudies. The following companies provided study medications, equipment, or supplies: Abbott Laboratories, Amylin Pharmaceutical, AstraZeneca Pharmaceuticals LP, Bayer HealthCare LLC, Closer Healthcare Inc., GlaxoSmithKline Pharmaceuticals, King Pharmaceuticals, Inc., Merck & Co., Inc., Novartis Pharmaceuticals, Inc., Novo Nordisk, Inc., Omron Healthcare, Inc., Sanofi-Aventis U.S., and Takeda Pharmaceuticals, Inc.

The American Diabetes Association is leading the fight to stop diabetes and its deadly consequences and fighting for those affected by diabetes. The Association funds research to prevent, cure and manage diabetes; delivers services to hundreds of communities; provides objective and credible information; and gives voice to those denied their rights because of diabetes. Founded in 1940, our mission is to prevent and cure diabetes and to improve the lives of all people affected by diabetes. For more information please call the American Diabetes Association at 1-800-DIABETES (1-800-342-2383) or visit www.diabetes.org. Information from both these sources is available in English and Spanish.

Symposium, June 29, 10:15 a.m.

Contact:
Christine Feheley
(703) 253-4374

Colleen Fogarty
(703) 549-1500, ext. 2146

News Room: June 25-29, 2010
Room 303B, Orange County Convention Center
(407) 685-4010

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Filed Under: Public Health and Research

Avaya Aids Study to Evolve Veteran’s Affairs Healthcare Information Technology System

Posted on June 29, 2010 Written by Editor

SOURCE: Avaya Inc.

Foundation of Quality V.A. Healthcare Information System to Modernize, Migrate to Open-Standards

FAIRFAX, VA–(Marketwire – June 29, 2010) –  Avaya Government Solutions, a wholly owned subsidiary of Avaya, today announced the company’s participation in the recently-released study to modernize the healthcare system used by the Department of Veterans Affairs (V.A.). The V.A. relies heavily on this system to ensure America’s Veterans receive the treatment they require. Called the “VistA Modernization Report – Legacy to Leadership,” it is focused on improving the V.A.’s VistA (V.A. Health Information Systems and Technology Architecture) healthcare network.

The V.A. has seen an uptake in the demands of its healthcare system; which must serve nearly eight million veterans, 153 V.A. hospitals and 768 outpatient clinics. VistA is the integrated health information system — recognized as one of the best in the nation — that supports the V.A. in its work.

“The V.A. relies on the best doctors and medical technology,” said Joel Hackney, president, Avaya Government Solutions. “We are honored to be chosen to contribute to the success of this study and help the V.A. make its next-generation, information network the best available. We support the work of the VistA study participants and thank them for their unique contributions in helping define the next-generation Healthcare IT vision.”

“Providing for those who have served this great nation is more than our mandate, it is our passion,” said the Honorable Roger Baker, assistant secretary for Information and Technology and Chief Information Officer, Veterans Affairs. “The VistA study provides critical insight from the leaders in industry as to how we can do this better, more effectively and more comprehensively. This is planned to enable us to employ our resources with laser precision, eliminating waste in terms of time to service and completely eliminating every unused or underused resource.”

Included in the recommendations of the VistA study is the need to migrate the design of the information system of the Veterans Affairs to an open, plug-and-play architecture so that the most modern and “built for purpose” components that enhance functionality can be incorporated. In addition, by moving to an open-standards approach, the VistA system can utilize the best technology from standards-compliant vendors as well as other open source communities that will provide the best, most innovative products in the future.

The VistA study was spearheaded by the American Council for Technology (ACT) – Industry Advisory Council (IAC), which promotes government and industry collaboration. It was managed by the V.A. and Andy Robinson, IAC executive vice chair, for the IAC Executive Committee. Ed Meagher, chair of the IAC VistA Modernization Working Group, led the working group of healthcare and IT professionals from 34 companies for the six-month study, which included co-chair of the VistA Modernization & Architecture subcommittee, Srinath Godavarthi, technical director, Avaya Government Solutions.

Enterprise network modernization is critical for all healthcare entities. HIPPA compliance has mandated that all such systems be ultra-secure in their totality with no margin for error. Avaya is focused on serving the needs of both the Civil Government and Federal Government as well as the Healthcare industry.

About Avaya Government Solutions
Avaya Government Solutions is a network-centric integrator, providing the services expertise, mission-critical systems and secure communications that empower government to ensure the security, livelihood, and well being of its citizens. Headquartered in Fairfax, Va., Avaya Government Solutions offers a one-stop shop for solutions designed to improve workforce productivity, reduce operating costs, and streamline inter-agency communications. Please visit www.Avayagov.com for more information.

About Avaya
Avaya is a global leader in enterprise communications systems. The company provides unified communications, contact centers, data solutions, and related services directly and through its channel partners to leading businesses and organizations around the world. Enterprises of all sizes depend on Avaya for state-of-the-art communications that improve efficiency, collaboration, customer service and competitiveness. For more information please visit www.avaya.com.

Media Inquiries:
Pat Cooper
Avaya Government Solutions
425-829-8572
[email protected]

Filed Under: Health Technology and AI, Public Health and Research

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